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AVI BioPharma, MDA to initiate exon-51 Phase 2 trial in Duchenne muscular dystrophy

More than a decade of targeted Muscular Dystrophy Association-funded research, made possible as a result of generous public support of the MDA Labor Day Telethon and thousands of grass-roots special events, has today culminated in MDA providing financial assistance for the start of the first Phase 2 placebo-controlled, multiple dose efficacy, safety, tolerability and pharmacokinetics clinical trial of an exon-51 skipping drug, eteplirsen, as a potential therapy for Duchenne muscular dystrophy.

16 Aug 2011

MRI scans show children of depressed mothers have enlarged amygdala

Researchers think that brains are sensitive to the quality of child care, according to a study that was directed by Dr. Sonia Lupien and her colleagues from the University of Montreal published today in the Proceedings of the National Academy of Sciences.

16 Aug 2011

An hour of TV a day shortens lifespan by 22 minutes: Study

Researchers have found that watching too much TV is as dangerous as smoking or being overweight, and that the “ubiquitous sedentary behaviour” should be seen as a “public health problem”.

16 Aug 2011

Toclizumab for juvenile rheumatoid arthritis

The arthritis drug Toclizumab could be a boon for hundreds of children suffering from severe arthritis. It has been re-launched in children after being already licensed for the treatment of adults. At least two thirds of children taking tocizilumab have been able to return to a normal life, after many were bedridden or forced into wheelchairs by the disease, the clinical studies reveal.

16 Aug 2011

Somalia faces cholera epidemic

World Health Organization (WHO) officials announced last Friday that famine-stricken Somalia faces a cholera epidemic as dirty water and poor sanitation are leading to an increase in outbreaks of the disease. The reports reveal cases of acute watery diarrhea - an important indicator of the risk of cholera - are now at 4,272 in Somalia - an 11 percent increase from last week’s WHO reported figure of 3,839.

15 Aug 2011

Increase in public awareness leads to lower obesity in children

Increasing public awareness of the childhood obesity epidemic may be contributing to evidence of overall reductions in body mass index (BMI), a measure of obesity in children, according to the results of a nationwide study presented in Childhood Obesity, a peer-reviewed journal published by Mary Ann Liebert, Inc.

12 Aug 2011

Mixed reports from aid organizations in Somalia after al-Shabab pulls out of Mogadishu

The news from the Horn of Africa is "mixed," NPR's "All Things Considered" reports, adding, "More food is getting through and security has improved for now, but tens of thousands of children have already died and many more are at risk." According to NPR, "Aid groups were pleased last week when al-Shabab, which the U.S. considers a terrorist organization, pulled out of the capital, Mogadishu. That made a dangerous country a little bit less so for aid workers".

12 Aug 2011

Episodic memory depends on the hippocampus

Memory is not a single process but is made up of several sub-processes relying on different areas of the brain. Episodic memory, the ability to remember specific events such as what you did yesterday, is known to be vulnerable to brain damage involving the hippocampus. The question is, what happens when damage to the hippocampus occurs very early in life?

12 Aug 2011

Pro-eugenic Yale psychologist's deception discovered

A University of New Hampshire researcher has discovered that a former Yale professor who espoused pro-eugenic beliefs manipulated his research findings so he could conclude that his Wisconsin home town was overflowing with mentally and morally "unfit" people.

12 Aug 2011

HHS moves ahead to establish Affordable Insurance Exchanges

The Departments of Health and Human Services and Treasury today took the next steps to establish Affordable Insurance Exchanges - one-stop marketplaces where consumers can choose a private health insurance plan that fits their health needs and have the same kind of insurance choices as members of Congress.

12 Aug 2011

International community, especially China, must invest more in African agriculture and health

A drought and "security crisis as a result of political conflicts, civil war and anarchy" in Somalia are to blame for the famine recently declared by the U.N., but "[t]he international community is also to blame for responding too slowly and neglecting its responsibilities in this preventable disaster," a Lancet editorial says.

12 Aug 2011

States slashing at least $4.7 billion from Medicaid plans

Reuters reports on a study of the state cuts by the Center on Budget and Policy Priorities. Also, Blue Cross Blue Shield of Michigan is looking to expand its Medicaid business and a California study explores the high number of young people without insurance.

12 Aug 2011

Sinovac second quarter sales increase 52.5% to $15.7 million

Sinovac Biotech Ltd., a leading provider of biopharmaceutical products in China, announced today its unaudited second quarter financial results for the period ended June 30, 2011.

12 Aug 2011

Biomarkers may transform diagnosis of kidney disease

Acute kidney injury (AKI) is a common - but preventable -- complication after surgery that can lead to other complications or even death. The use and development of biomarkers will help physicians diagnose and treat acute kidney injury.

12 Aug 2011

Study finds decrease in inpatient hospitalizations for the elderly with psychiatric diagnosis

Short-stay inpatient hospitalizations for children and adolescents with a psychiatric diagnosis increased significantly over a 12-year period (1996 to 2007) and decreased for the elderly, according to a report in the early online edition in Archives of General Psychiatry by Joseph C. Blader, Ph.D., Assistant Professor, Department of Psychiatry & Behavioral Science at Stony Brook University School of Medicine.

12 Aug 2011

Feeling the budget squeeze, some states reduce kids' access to care

According to the National Association of Children's Hospitals and Related Institutions, a majority of state-level changes to Medicaid this year reduced benefits or reimbursement rates for children's services.

12 Aug 2011

What will the panelists bring to the 'super committee' negotiations?

News outlets report on the personalities and records of the people who have been named to the deficit panel, and attempt to handicap how their politics could play into the deficit-reduction dynamics.

12 Aug 2011

MYCN amplification can serve as a favorable prognostic indicator for neuroblastoma

Neuroblastoma, a malignant tumor that primarily affects infants and young children, is a leading cause of death for children with cancer. When amplification of the MYCN oncogene is found in the tumor, it usually indicates an aggressive tumor with rapid progression of the disease and a poor outcome. Thus MYCN amplification has come to be used as a prognostic indicator.

12 Aug 2011

NSAIDs like ibuprofen slow the spread of breast cancers

Published online on Aug. 7, 2011, the journal Nature Medicine reports that non-steroidal anti-inflammatory drugs including ibuprofen reduce the severity of postpartum breast cancers in animal models.

12 Aug 2011

Pregnant women lack enough vitamin D despite use of prenatal supplements

Pregnant women taking prenatal supplements may not be getting enough vitamin D, shows a new Vancouver-based study led by the Child & Family Research Institute at BC Children's Hospital that was published in the Canadian Journal of Public Health.

12 Aug 2011