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FDA agrees to allow ADial to move forward with Phase III trial of AD04 for alcohol use disorder

ADial Pharmaceuticals, LLC, announced today that the U.S. Food and Drug Administration has agreed to allow ADial to move forward with its plan to initiate Phase III trials of AD04 as a treatment for alcohol use disorder in certain targeted genotypes population only.

19 Apr 2013

Elevated responsivity of reward regions in the brain increases risk for future substance use

Do people get caught in the cycle of overeating and drug addiction because their brain reward centers are over-active causing them to experience greater cravings for food or drugs? In a unique prospective study Oregon Research Institute senior scientist Eric Stice, Ph.D., and colleagues tested this theory, called the reward surfeit model.

19 Apr 2013

Health law creates challenges for various parts of the system

News outlets report on a variety of implementation issues, including the question of how to provide treatment for the millions of people with addiction and alcohol dependencies who will have insurance for the first time and the difficulties faced by safety-net hospitals.

18 Apr 2013

First Edition: April 17, 2013

Today's headlines include reports about a new study finding that surgical woes can actually bolster a hospital's profits.

17 Apr 2013

Researchers use miniature electronic device to tap into internal reward system of mice

Using a miniature electronic device implanted in the brain, scientists have tapped into the internal reward system of mice, prodding neurons to release dopamine, a chemical associated with pleasure.

15 Apr 2013

Androgen receptors found to be a potential target in breast cancer

Estrogen and progesterone receptors, and the gene HER2 - these are the big three markers and/or targets in breast cancer. Evidence presented at the AACR Annual Meeting 2013 adds a fourth: androgen receptors.

11 Apr 2013

Viewpoints: Looking for the budget's true bottom line; The debate on Plan B reignited; Medicare cuts have impact

President Obama will release his overdue budget on Wednesday. It will doubtless project a reduction in the federal budget deficit - a projection that journalists, commentators and policy makers should ignore.

10 Apr 2013

Most Americans concerned about misuse of pain medication to treat chronic pain

A new national public opinion poll commissioned by Research!America shows only 18% of respondents believe chronic pain is a major health problem, even though a majority of Americans (63%) say they know someone who experienced pain so severe that they sought prescription medicines to treat it.

10 Apr 2013

Weill Cornell Medical College sets up new Feil Family Brain and Mind Research Institute

Weill Cornell Medical College has established the new Feil Family Brain and Mind Research Institute, a unique, multidisciplinary translational neuroscience research hub. Named in honor of long-time benefactors Gertrude and Louis Feil, the institute was created with a generous $28 million gift from the Feil Family.

9 Apr 2013

New national study examines marijuana use and prescription drug misuse

Individuals who use marijuana recreationally are more likely to misuse other drugs, including pain-controlling, but potentially addictive narcotics, sedatives and other prescription medications, than individuals who do not use marijuana, according to a new national study issued today by Quest Diagnostics, the world's leading provider of diagnostic information services.

From Quest Diagnostics 9 Apr 2013

ISP of Chile approves Trigemina's protocol for Phase 2 clinical study of TI-001

Trigemina, Inc., a biopharmaceutical company focused on the discovery and development of non-narcotic, nasally delivered, analgesic drug products, today announced that the Instituto de Salud Publica of Chile has approved the Company's protocol for its Phase 2 clinical study of TI-001, intranasal oxytocin, for the treatment of chronic migraine.

9 Apr 2013

Migraine sufferers should undergo more formal experiments, says study

Women often point to stress, hormones, alcohol, or even the weather as possible triggers for their migraines. But a new study from Wake Forest Baptist Medical Center found that it is nearly impossible for patients to determine the true cause of their migraine episodes without undergoing formal experiments.

8 Apr 2013

Study: Altering brain activity with laser light eliminates addictive behavior in rats

By stimulating one part of the brain with laser light, researchers at the National Institutes of Health (NIH) and the Ernest Gallo Clinic and Research Center at UC San Francisco (UCSF) have shown that they can wipe away addictive behavior in rats - or conversely turn non-addicted rats into compulsive cocaine seekers.

4 Apr 2013

Study shows relationship between cocaine-induced brain deficits in prefrontal cortex and cocaine-seeking

Could drug addiction treatment of the future be as simple as an on/off switch in the brain? A study in rats has found that stimulating a key part of the brain reduces compulsive cocaine-seeking and suggests the possibility of changing addictive behavior generally.

4 Apr 2013

Research finds links between cannabis and mental illness

People with mental illnesses are more than seven times more likely to use cannabis weekly compared to people without a mental illness, according to researchers from the Centre for Addiction and Mental Health (CAMH) who studied U.S. data.

3 Apr 2013

Years after law, former congressman continues mental health coverage parity battle

Despite a mental health parity law passed in 2008, one of the measure's key backers -- former Congressman Patrick Kennedy -- continues the fight for equal coverage of mental illness and is meeting mixed success.

2 Apr 2013

Researchers use common virus to modify adult stem cells

Using the same strategy that a common virus employs to evade the human immune system, researchers at Wake Forest Baptist Medical Center's Institute for Regenerative Medicine have modified adult stem cells to increase their survival - with the goal of giving the cells time to exert their natural healing abilities.

2 Apr 2013

Study suggests children of deployed parents face increase risk for alcohol and drugs usage

In 2010, almost 2 million American children had at least one parent in active military duty. A new University of Iowa study suggests that deployment of a parent puts these children at an increased risk for drinking alcohol and using drugs.

29 Mar 2013

TSRI scientists receive innovative grant to help people break nicotine addiction

As part of an unprecedented national effort to develop new drugs to treat neurological disorders, scientists from the Florida campus of The Scripps Research Institute (TSRI) have been awarded an innovative grant from the National Institute of Neurological Disorders and Stroke to help people break their addiction to nicotine.

28 Mar 2013

TSRI scientists awarded innovative grant to develop anti-smoking drug candidates

As part of an unprecedented national effort to develop new drugs to treat neurological disorders, scientists from the Florida campus of The Scripps Research Institute have been awarded an innovative grant from the National Institute of Neurological Disorders and Stroke to help people break their addiction to nicotine.