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Montreal-based researchers get closer to achieving healthy longevity

Hearing loss, brittle bones, sagging skin, a deteriorating mind: these are just some of the issues associated with growing old.

7 Sep 2016

Fraunhofer researchers plan to use electron beams to remove germs from tissue transplants

Medical products, packaging and food can be safely and efficiently sterilized with electron beams.

7 Sep 2016

TSRI researchers find way to switch off urge for compulsive drinking in rat models

There may be a way to switch off the urge for compulsive drinking, according to a new study in animal models led by scientists at The Scripps Research Institute.

6 Sep 2016

Monoclonal antibody removes brain amyloid plaques in patients with Alzheimer's disease

Scientists at Neurimmune today described results from the Phase 1b PRIME clinical trial of the monoclonal antibody aducanumab.

1 Sep 2016

Novel drug delivery system may offer new hope for patients with rare fatal genetic disorder

Researchers at Oregon State University and other institutions have discovered a type of drug delivery system that may offer new hope for patients with a rare, ultimately fatal genetic disorder - and make what might become a terrible choice a little easier.

30 Aug 2016

Novel compound provides safe, effective pain relief with zero abuse potential in animal model

Since the isolation of morphine from opium in the 19th century, scientists have hoped to find a potent opioid analgesic that isn't addictive and doesn't cause respiratory arrest with increased doses.

30 Aug 2016

Study examines link between PTSD and cognitive impairment in WTC responders without head injury

New research published by the journal Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring confirms the connection between posttraumatic stress disorder (PTSD) and cognitive impairment - in this case, among those who helped with search, rescue and cleanup efforts following the 2001 World Trade Center (WTC) attacks.

30 Aug 2016

NCATS scientists identify promising compounds effective in inhibiting Zika virus replication

Researchers at the National Center for Advancing Translational Sciences recently identified compounds that potentially can be used to inhibit Zika virus replication and reduce its ability to kill brain cells.

29 Aug 2016

Janssen seeks to extend DARZALEX license to benefit more multiple myeloma patients

Janssen-Cilag International NV has announced the submission of a Type II variation application to the European Medicines Agency (EMA), seeking to broaden the existing marketing authorisation for the immunotherapy DARZALEX® (daratumumab) to include treatment of adult patients with relapsed multiple myeloma who have received at least one prior therapy. The expanded indication is based on daratumumab in combination with lenalidomide (an immmunomodulatory agent) and dexamethasone, or bortezomib (a PI) and dexamethasone.

29 Aug 2016

$New study finds contamination events near fracking gas drilling sites result of operational inefficiencies$

New study finds contamination events near fracking gas drilling sites result of operational inefficiencies

Chemists at the University of Texas at Arlington have published a new study that indicates that highly variable contamination events registered in and around unconventional oil and gas developments are the result of operational inefficiencies and not inherent to the extraction process itself.

26 Aug 2016

Anesthetic administered with nasal spray effective in preventing pain during dental treatment

A fear of pain causes many people with dental phobias to avoid or delay needed treatment. In some cases, the injection of a numbing agent can be the most painful part of the visit.

26 Aug 2016

Researchers find new way for early prediction of leukemic relapse

Researchers at University of California San Diego School of Medicine and Moores Cancer Center have identified RNA-based biomarkers that distinguish between normal, aging hematopoietic stem cells and leukemia stem cells associated with secondary acute myeloid leukemia (sAML), a particularly problematic disease that typically afflicts older patients who have often already experienced a bout with cancer.

26 Aug 2016

Novel small-molecule Wnt inhibitor may provide new treatment option for colorectal cancer patients

A team including the National Cancer Center, the RIKEN Center for Life Science Technologies , and Carna Biosciences Inc., has jointly announced the development of a novel small-molecule Wnt inhibitor named NCB-0846.

26 Aug 2016

Cedars-Sinai study identifies metabolic enzyme that alerts the body to invading bacteria

Biomedical investigators at Cedars-Sinai have identified an enzyme found in all human cells that alerts the body to invading bacteria and jump-starts the immune system.

25 Aug 2016

UNC researchers map anxiety circuit in the brain that may explain side effects of antidepressants

More than 100 million people worldwide take selective serotonin reuptake inhibitors (SSRIs), such as Prozac and Zoloft, to treat depression, anxiety and related conditions, but these drugs have a common and mysterious side effect: they can worsen anxiety in the first few weeks of use, which leads many patients to stop treatment.

25 Aug 2016

New chemical compound could potentially be used to treat Ebola virus infection

Scientists have found Ebola's Achilles' heel: a new kind of chemical compound can block the protein Ebola uses to break out of cells and infect new cells.

24 Aug 2016

TSRI scientists find evidence supporting new therapeutic strategy against cocaine addiction

An international team led by scientists at The Scripps Research Institute has found strong evidence supporting a new strategy against drug addiction.

18 Aug 2016

Penn researchers uncover strategy to reverse effects of dyskeratosis congenita

Dyskeratosis congenita, or DC, is a rare, inherited disease for which there are limited treatment options and no cure.

18 Aug 2016

Novel marine natural product appears to reduce pancreatic tumor size

Scientists at Florida Atlantic University's Harbor Branch Oceanographic Institute found that a deep-water marine sponge collected off of Fort Lauderdale's coast contains leiodermatolide, a natural product that has the ability to inhibit the growth of cancer cells as well as block cancer cells from dividing using extremely low concentrations of the compound.

18 Aug 2016

IRB Barcelona scientists rediscover utility of disordered proteins as therapeutic targets

Prostate cancer, Alzheimer's, Parkinson's...these three diseases are associated with proteins that share a common feature, namely disordered regions that have no apparent rigid three-dimensional structure.

16 Aug 2016

Compound News and Research

Montreal-based researchers get closer to achieving healthy longevity

Fraunhofer researchers plan to use electron beams to remove germs from tissue transplants

TSRI researchers find way to switch off urge for compulsive drinking in rat models

Monoclonal antibody removes brain amyloid plaques in patients with Alzheimer's disease

Novel drug delivery system may offer new hope for patients with rare fatal genetic disorder

Novel compound provides safe, effective pain relief with zero abuse potential in animal model

Study examines link between PTSD and cognitive impairment in WTC responders without head injury

NCATS scientists identify promising compounds effective in inhibiting Zika virus replication

Janssen seeks to extend DARZALEX license to benefit more multiple myeloma patients

New study finds contamination events near fracking gas drilling sites result of operational inefficiencies

Anesthetic administered with nasal spray effective in preventing pain during dental treatment

Researchers find new way for early prediction of leukemic relapse

Novel small-molecule Wnt inhibitor may provide new treatment option for colorectal cancer patients

Cedars-Sinai study identifies metabolic enzyme that alerts the body to invading bacteria

UNC researchers map anxiety circuit in the brain that may explain side effects of antidepressants

New chemical compound could potentially be used to treat Ebola virus infection

TSRI scientists find evidence supporting new therapeutic strategy against cocaine addiction

Penn researchers uncover strategy to reverse effects of dyskeratosis congenita

Novel marine natural product appears to reduce pancreatic tumor size

IRB Barcelona scientists rediscover utility of disordered proteins as therapeutic targets

Enhancing confidence in chemical ionization spectrometry data eBook

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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