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Period of observation can avoid unnecessary head CT scan use in children

Overall, roughly half of U.S. children taken to hospital emergency departments for a head injury receive a head CT scan, often to ease worried parents' concerns. Yet true traumatic brain injury is uncommon.

9 May 2011

Brain cancer research needs $50 billion to find cure

According to one of Australia's leading neurosurgeons a massive increase in funding is needed to find a cure for brain cancer. Brain cancer kills one Australian every eight hours. About 1,400 cases of malignant brain cancer are diagnosed in Australia every year and about 1,100 people die from the disease.

8 May 2011

WWP2 protein appears to play a key role in tumor survival

A protein known as WWP2 appears to play a key role in tumor survival, a research team headed by a scientist at The University of Texas MD Anderson Cancer Center reports in an advance online publication of Nature Cell Biology.

4 May 2011

Temsirolimus with chemotherapy may serve as promising therapy for mesothelioma

A drug commonly used to treat kidney cancer may increase the effectiveness of chemotherapy for mesothelioma, according to a study published in the May issue of the Journal of Thoracic Oncology.

2 May 2011

No proven advantages of PET for diagnostic accuracy of head and neck tumours: Research

The benefit and harm of positron emission tomography in patients with head and neck tumours, applied alone or in combination with computed tomography, cannot currently be reliably assessed.

30 Apr 2011

MarginProbe System meets its primary endpoints: Dune Medical Devices

Dune Medical Devices, Inc. today announced that the landmark, 664-patient pivotal trial evaluating the MarginProbe System met its primary endpoints. The MarginProbe System provides surgeons with a real time, intraoperative technology to detect microscopically-positive margins on excised tissues.

30 Apr 2011

Three hundred neurosurgeons to participate in Central Park softball tournament

With summer just around the corner, that means the Annual Neurosurgery Charity Softball Tournament will take place in Central Park for the eighth consecutive year.

30 Apr 2011

IOF, ANZBMS to hold osteoporosis and bone meeting in Asia-Pacific region

IOF and the ANZBMS, together with the Japanese Bone and Mineral Research Society, invite researchers and clinicians with an interest in osteoporosis and bone research to attend the year's most important bone meeting in the Asia-Pacific region.

29 Apr 2011

Unanticipated structure at chromosome ends could be key ingredient in biological 'elixir of life'

In stark contrast to normal cells, which only divide a finite number of times before they enter into a permanent state of growth arrest or simply die, cancer cells never cease to proliferate. Now, scientists at the Salk Institute for Biological Studies have uncovered an important clue to one of the mechanisms underlying cancer cell immortality.

22 Apr 2011

Study finds ACE inhibitors linked to increased risk of recurrence in women who have had breast cancer

ACE inhibitors, commonly used to control high blood pressure and heart failure in women, may be associated with an increased risk of recurrence in women who have had breast cancer, according to a study by researchers at UCLA's Jonsson Comprehensive Cancer Center.

21 Apr 2011

Ludwig Institute demonstrates ability of DAVANAT to enhance efficacy of T-lymphocytes to kill tumor cells

Pro-Pharmaceuticals, Inc. today announced that the Brussels Branch of the Ludwig Institute for Cancer Research demonstrated the ability of GM-CT-01 (DAVANAT®) to enhance the ability of tumor-specific T-lymphocytes to kill tumor cells.

20 Apr 2011

Researchers discover new way to force cancer cells to self-destruct

Researchers at The Wistar Institute have found a new way to force cancer cells to self-destruct. Low doses of one anti-cancer drug currently in development, called Gamitrinib, sensitize tumor cells to a second drug, called TRAIL, also currently in clinical development as part of an anticancer regimen.

20 Apr 2011

Minimizing neurological side effects in high-grade glioma patients may improve survival

Minimizing neurological side effects in patients with high-grade glioma from chemoradiation may result in improved patient survival, a new study from radiation oncologists at the Kimmel Cancer Center at Jefferson suggests. These findings were reported in the April issue of the British Journal of Cancer.

20 Apr 2011

Study finds more evidence linking high-grade serous ovarian cancer to fallopian tubes

High-grade serous ovarian cancer (HGSOC), the fifth-deadliest cancer among American women, is thought by many scientists to often be a fallopian tube malignancy masquerading as an ovarian one. While most of the evidence linking HGSOC to the fallopian tubes has so far been only circumstantial, a new Dana-Farber Cancer Institute study suggests there is a direct connection, a finding that could aid in the development of better treatments for the cancer.

19 Apr 2011

New results from largest multicenter clinical trial for heart transplant patients be released at ISHLT 2011

New results from the largest multicenter clinical trial for heart transplant patients will be released this week at the International Society for Heart & Lung Transplantation 31st Annual Meeting and Scientific Sessions in San Diego. Results show clinical benefit for the use of Everolimus in heart transplant patients.

16 Apr 2011

Proteins could lead to new therapeutic target for NF2: Wistar Institute researchers

The proteins that provide cells with a sense of personal space could lead to a therapeutic target for Neurofibromatosis Type 2, an inherited cancer disorder, according to researchers at The Wistar Institute. Their findings, which appear in the April 12 issue of the journal Cancer Cell, could have profound implications for NF2 and related cancers, such as mesothelioma.

16 Apr 2011

Normal breast cells provide an innate defense mechanism against cancer

It is well known that the human body has a highly developed immune system to detect and destroy invading pathogens and tumor cells. Now, researchers at the U.S. Department of Energy's Lawrence Berkeley National Laboratory (Berkeley Lab) have shown that the body has a second line of defense against cancer - healthy cells.

15 Apr 2011

Positive results from ULCA's Phase 1 dendritic cell vaccine trial in glioblastoma

A novel brain tumor vaccine clinical trial study demonstrates a longer survival time in patients with glioblastoma, according to findings being presented at the 79th Annual Scientific Meeting of the American Association of Neurological Surgeons in Denver.

12 Apr 2011

Alternative mechanism through which tumor cells become invasive

Researchers at the Hebrew University of Jerusalem have discovered a previously unknown mechanism whereby tumor cells invade normal tissues, spreading cancer through various organs.

12 Apr 2011

Novel drug holds potential against resistant chronic myeloid leukemia

A study from Tufts Medical Center researchers published today finds that a novel drug shows promise for treating leukemia patients who have few other options because their disease has developed resistance to standard treatment.

12 Apr 2011

Malignant News and Research

Period of observation can avoid unnecessary head CT scan use in children

Brain cancer research needs $50 billion to find cure

WWP2 protein appears to play a key role in tumor survival

Temsirolimus with chemotherapy may serve as promising therapy for mesothelioma

No proven advantages of PET for diagnostic accuracy of head and neck tumours: Research

MarginProbe System meets its primary endpoints: Dune Medical Devices

Three hundred neurosurgeons to participate in Central Park softball tournament

IOF, ANZBMS to hold osteoporosis and bone meeting in Asia-Pacific region

Unanticipated structure at chromosome ends could be key ingredient in biological 'elixir of life'

Study finds ACE inhibitors linked to increased risk of recurrence in women who have had breast cancer

Ludwig Institute demonstrates ability of DAVANAT to enhance efficacy of T-lymphocytes to kill tumor cells

Researchers discover new way to force cancer cells to self-destruct

Minimizing neurological side effects in high-grade glioma patients may improve survival

Study finds more evidence linking high-grade serous ovarian cancer to fallopian tubes

New results from largest multicenter clinical trial for heart transplant patients be released at ISHLT 2011

Proteins could lead to new therapeutic target for NF2: Wistar Institute researchers

Normal breast cells provide an innate defense mechanism against cancer

Positive results from ULCA's Phase 1 dendritic cell vaccine trial in glioblastoma

Alternative mechanism through which tumor cells become invasive

Novel drug holds potential against resistant chronic myeloid leukemia

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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