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UNC researchers find new enzyme target for treating chronic pain

Researchers at the UNC School of Medicine have found a new target for treating chronic pain: an enzyme called PIP5K1C.

22 May 2014

New compound restores learning, memory and other symptoms of AD in mice

A molecular compound developed by Saint Louis University scientists restored learning, memory and appropriate behavior in a mouse model of Alzheimer's disease, according to findings in the May issue of the Journal of Alzheimer's Disease.

21 May 2014

Study: E-cigarettes appear to increase virulence of drug- resistant and life-threatening bacteria

Despite being touted by their manufacturers as a healthy alternative to cigarettes, e-cigarettes appear in a laboratory study to increase the virulence of drug- resistant and potentially life-threatening bacteria, while decreasing the ability of human cells to kill these bacteria

19 May 2014

Global scientists to discuss latest findings on diagnosis, causes and treatments of ASD

The International Society for Autism Research (INSAR), a scientific and professional organization devoted to advancing knowledge about autism spectrum disorders, convened more than 1700 researchers, delegates, autism specialists and students from 40 countries for the 13th Annual International Meeting for Autism Research (IMFAR), the world's largest scientific gathering on autism research, from May 15 through May 17 at the Atlanta Marriott Marquis in Atlanta, GA.

15 May 2014

Antidepressant stops growth of plaques in mouse model of Alzheimer's disease

A commonly prescribed antidepressant can reduce production of the main ingredient in Alzheimer's brain plaques, according to new research at Washington University School of Medicine in St. Louis and the University of Pennsylvania.

15 May 2014

Scientists discover novel protein fragments that may protect against Alzheimer's disease

The devastating loss of memory and consciousness in Alzheimer's disease is caused by plaque accumulations and tangles in neurons, which kill brain cells.

14 May 2014

2 genes work together to drive most lethal forms of prostate cancer

Two genes work together to drive the most lethal forms of prostate cancer, according to new research from the Herbert Irving Comprehensive Cancer Center at Columbia University Medical Center (CUMC).

13 May 2014

S. pneumoniae interacts with other nasopharyngeal bacteria

Streptococcus pneumoniae bacteria are able to detect and respond to other bacterial species in the same host niche, researchers report in Open Biology.

12 May 2014

Inovio Pharmaceuticals reports total revenue of $2.4 million for first quarter 2014

Inovio Pharmaceuticals, Inc. today reported financial results for the quarter ended March 31, 2014.

12 May 2014

Biochemists identify protein that can slow down growth of brain tumors in mice

Much like using dimmer switches to brighten or darken rooms, biochemists have identified a protein that can be used to slow down or speed up the growth of brain tumors in mice.

12 May 2014

Anti-cancer drug delivery method smuggles drug into cancer cell before triggering release

Biomedical engineering researchers have developed an anti-cancer drug delivery method that essentially smuggles the drug into a cancer cell before triggering its release.

12 May 2014

New study associates sex difference in brain with MS

A newly identified difference between the brains of women and men with multiple sclerosis (MS) may help explain why so many more women than men get the disease, researchers at Washington University School of Medicine in St. Louis report.

9 May 2014

Form of baclofen works better at treating narcolepsy

Neuroscientists at SRI International have found that a form of baclofen, a drug used to treat muscle spasticity, works better at treating narcolepsy than the best drug currently available when tested in mice.

8 May 2014

Protein molecule seems to slow progression of deadly lung disease

Researchers at the University of Illinois at Chicago College of Medicine have discovered a protein molecule that seems to slow the progression of pulmonary fibrosis, a progressive lung disease that is often fatal three to five years after diagnosis.

7 May 2014

Nanoviricides develops new drug candidates against MERS infection

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6 May 2014

Characterization of Cajal-Retzius cells during development in mouse model of Alzheimer's disease

Cajal-Retzius cells are reelin-secreting neurons in the marginal zone of the neocortex and hippocampus.

6 May 2014

Scientists develop experimental drug that prolongs lifespan in mouse model of accelerated aging

Northwestern Medicine- scientists have newly identified a protein's key role in cell and physiological aging and have developed - in collaboration with Tohoku University in Japan -- an experimental drug that inhibits the protein's effect and prolonged the lifespan in a mouse model of accelerated aging.

2 May 2014

Research helps unpick long-standing mystery about how dietary fibre supresses appetite

New research has helped unpick a long-standing mystery about how dietary fibre supresses appetite. In a study led by Imperial College London and the Medical Research Council (MRC), an international team of researchers identified an anti-appetite molecule called acetate that is naturally released when we digest fibre in the gut.

30 Apr 2014

Adhesion molecule offers promising therapeutic target for preventing colitis

May Provide Therapeutic Target for Treating Inflammatory Bowel Disease and Preventing Colitis-Associated Colorectal Cancer, According to New Research Published in The American Journal of Pathology

29 Apr 2014

Study shows pro-inflammatory cytokine TNF-α can speed recovery in mouse with pulmonary fibrosis

Inflammation has long been considered an integral part of the biological process that leads to deadly scarring in idiopathic pulmonary fibrosis. New research at National Jewish Health, however, suggests that a little inflammation may also be crucial to the healing and repair processes in the lungs.

26 Apr 2014

Mouse Model News and Research

UNC researchers find new enzyme target for treating chronic pain

New compound restores learning, memory and other symptoms of AD in mice

Study: E-cigarettes appear to increase virulence of drug- resistant and life-threatening bacteria

Global scientists to discuss latest findings on diagnosis, causes and treatments of ASD

Antidepressant stops growth of plaques in mouse model of Alzheimer's disease

Scientists discover novel protein fragments that may protect against Alzheimer's disease

2 genes work together to drive most lethal forms of prostate cancer

S. pneumoniae interacts with other nasopharyngeal bacteria

Inovio Pharmaceuticals reports total revenue of $2.4 million for first quarter 2014

Biochemists identify protein that can slow down growth of brain tumors in mice

Anti-cancer drug delivery method smuggles drug into cancer cell before triggering release

New study associates sex difference in brain with MS

Form of baclofen works better at treating narcolepsy

Protein molecule seems to slow progression of deadly lung disease

Nanoviricides develops new drug candidates against MERS infection

Characterization of Cajal-Retzius cells during development in mouse model of Alzheimer's disease

Scientists develop experimental drug that prolongs lifespan in mouse model of accelerated aging

Research helps unpick long-standing mystery about how dietary fibre supresses appetite

Adhesion molecule offers promising therapeutic target for preventing colitis

Study shows pro-inflammatory cytokine TNF-α can speed recovery in mouse with pulmonary fibrosis

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