OCT News and Research

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Genome engineering-based methods pave way for new treatment of patients with sickle cell disease

A team of physicians and laboratory scientists has taken a key step toward a cure for sickle cell disease, using CRISPR-Cas9 gene editing to fix the mutated gene responsible for the disease in stem cells from the blood of affected patients.

12 Oct 2016

Novel method can quantify progression of NAFLD to more advanced fibrosis and cirrhosis

Combining multiple non-invasive measures, researchers at University of California San Diego School of Medicine describe a novel method to quantify the progression of nonalcoholic fatty liver disease (NAFLD) to its more dangerous and deadly states — advanced fibrosis and cirrhosis.

12 Oct 2016

Yale researchers define genetic landscape of rare, aggressive carcinosarcomas

In a major breakthrough for ovarian and uterine cancers, Yale researchers have defined the genetic landscape of rare, highly aggressive tumors called carcinosarcomas (CSs), pointing the way to possible new treatments.

12 Oct 2016

High-protein diet eliminates metabolic benefits of weight loss in obese women

Dieters sometimes consume extra protein to stave off hunger and prevent loss of muscle tissue that often comes with weight loss.

12 Oct 2016

Calcium supplements may raise risk of plaque buildup in arteries and heart damage

After analyzing 10 years of medical tests on more than 2,700 people in a federally funded heart disease study, researchers at Johns Hopkins Medicine and elsewhere conclude that taking calcium in the form of supplements may raise the risk of plaque buildup in arteries and heart damage, although a diet high in calcium-rich foods appears be protective.

12 Oct 2016

Fighting malaria by altering human flavor

A new study by Johns Hopkins researchers suggests that a specialized area of the mosquito brain mixes tastes with smells to create unique and preferred flavors. The findings advance the possibility, they say, of identifying a substance that makes “human flavor” repulsive to the malaria-bearing species of the mosquitoes, so instead of feasting on us, they keep the disease to themselves, potentially saving an estimated 450,000 lives a year worldwide.

11 Oct 2016

Warmer weather linked to increase in traumatic injuries for agricultural workers

Warmer weather is related to an increase in traumatic injuries for outdoor agricultural workers in central and eastern Washington.

7 Oct 2016

Children’s consumption levels of sugary drinks linked to combo meals at fast-food restaurants

A new survey of children's and teenagers' eating habits at fast-food restaurants suggests that consumption levels of sugary drinks are closely tied to their automatic inclusion in "combo meal" packages.

7 Oct 2016

Johns Hopkins researchers identify protein that triggers brain cell death from strokes and injuries

Despite their different triggers, the same molecular chain of events appears to be responsible for brain cell death from strokes, injuries and even such neurodegenerative diseases as Alzheimer's.

7 Oct 2016

Has human lifespan reached its maximum limit?

By Sally Robertson, BSc According to a study published in Nature, the maximum human lifespan is fixed, has already been reached and is not likely to increase as time goes on.

6 Oct 2016

Researchers uncover potential role of gut bacteria in neurodegeneration

Alzheimer's disease (AD), Parkinson's disease (PD) and Amyotrophic Lateral Sclerosis (ALS) are all characterized by clumped, misfolded proteins and inflammation in the brain. In more than 90 percent of cases, physicians and scientists do not know what causes these processes to occur.

6 Oct 2016

Researchers find biological evidence linking Zika virus infection and Guillain-Barré syndrome

In a collaborative effort with scientists at six Colombian hospitals, Johns Hopkins Medicine researchers report what they believe to be the strongest biological evidence to date linking Zika virus infection and Guillain-Barré syndrome.

5 Oct 2016

Ramp-up tones could be effective alerting method to reduce stress on firefighters

An article published in the Journal of Occupational and Environmental Hygiene that examines long-term health effects suffered by emergency responders indicates that "ramp-up" alert tones can help reduce stress on firefighters.

5 Oct 2016

Scientists identify new pathway in the brain that can be targeted to alleviate depression

Northwestern Medicine scientists have discovered a new pathway in the brain that can be manipulated to alleviate depression. The pathway offers a promising new target for developing a drug that could be effective in individuals for whom other antidepressants have failed.

5 Oct 2016

Prion proteins can drive emergence of new traits and adaptive opportunities

Prion proteins, best known as the agents of deadly brain disorders like mad cow disease, can help yeast survive hard times and pass the advantageous traits down to their offspring, according to a new study by researchers at the Stanford University School of Medicine.

4 Oct 2016

Researchers find key risk factors for physical decline among survivors of ARDS

A new study by a team of Johns Hopkins researchers found that most survivors of acute respiratory distress syndrome (ARDS) decline physically in the five years after hospital discharge, and those at higher levels of risk of decline are older and had greater medical problems prior to hospitalization for ARDS.

3 Oct 2016

OCT News and Research

Genome engineering-based methods pave way for new treatment of patients with sickle cell disease

Novel method can quantify progression of NAFLD to more advanced fibrosis and cirrhosis

Yale researchers define genetic landscape of rare, aggressive carcinosarcomas

High-protein diet eliminates metabolic benefits of weight loss in obese women

Calcium supplements may raise risk of plaque buildup in arteries and heart damage

Fighting malaria by altering human flavor

Warmer weather linked to increase in traumatic injuries for agricultural workers

Children’s consumption levels of sugary drinks linked to combo meals at fast-food restaurants

Johns Hopkins researchers identify protein that triggers brain cell death from strokes and injuries

Has human lifespan reached its maximum limit?

Researchers uncover potential role of gut bacteria in neurodegeneration

Researchers find biological evidence linking Zika virus infection and Guillain-Barré syndrome

Ramp-up tones could be effective alerting method to reduce stress on firefighters

Scientists identify new pathway in the brain that can be targeted to alleviate depression

Prion proteins can drive emergence of new traits and adaptive opportunities

Researchers find key risk factors for physical decline among survivors of ARDS

Scientists find way to enhance, restore sensitivity to common treatment for breast cancer

USC researchers to demonstrate how wearable technology can improve cancer treatment

microDimensions to host two compact digital pathology webinars on 11 October, 2016

New study suggests major change in treatment of significant number of ACS patients

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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