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Designer DNA drug could be used to delay paralysis in ALS

In virtually all persons with amyotrophic lateral sclerosis (ALS) and in up to half of all cases of Alzheimer's disease (AD) and frontotemporal dementia, a protein called TDP-43 is lost from its normal location in the nucleus of the cell.

17 Mar 2023

Study reveals the underlying mechanism by which TKI cancer drugs cause inflammation

Tyrosine kinase inhibitors are a type of targeted cancer medicine that can attack specific types of cancer cells and prevent them from multiplying.

17 Mar 2023

Researchers fabricate first wearable sensor to detect and monitor muscle atrophy

Researchers at The Ohio State University have fabricated the first wearable sensor designed to detect and monitor muscle atrophy.

17 Mar 2023

CRISPR-based genome editing restores the vision of mice with retinitis pigmentosa

Researchers in China have successfully restored the vision of mice with retinitis pigmentosa, one of the major causes of blindness in humans.

17 Mar 2023

Is antenatal COVID-19–related stress associated with postpartum maternal mental health and infant outcomes?

Researchers assessed the relationship between COVID-19-associated stress in the antenatal period and the mental well-being of mothers and their infants in the postpartum period.

17 Mar 2023

Drug combination may reduce the risk of prostate cancer progression, death

TALAPRO-2, a study led by Neeraj Agarwal, MD, FASCO, demonstrated that using TALZENNA, in combination with XTANDI, may reduce the risk of disease progression or death by 37%.

17 Mar 2023

Stanford researchers study causes of and treatments for long COVID

Time heals many wounds. But not all of them.

17 Mar 2023

How the structural and functional effects of mutations on androgen receptor lead to prostate cancer

The androgen receptor is a key transcriptional factor for the proper sex development —specially in males— and the physiological balance of all the tissues that express this receptor.

17 Mar 2023

Genomic analysis of Ashaninka individuals reveals an unexpected amount of underlying diversity

The Ashaninka are the most numerous Indigenous people living in the rainforests of Peru and Brazil where they inhabit a crucial area between the Andes and sources of the Amazon River. And yet, despite the size of the population and their importance in the past and present, their genetic history has remained understudied.

17 Mar 2023

Computational analysis of large genetic datasets reveals rare disease etiologies

Using a new computational approach they developed to analyze large genetic datasets from rare disease cohorts, researchers at the Icahn School of Medicine at Mount Sinai and colleagues have discovered previously unknown genetic causes of three rare conditions: primary lymphedema (characterized by tissue swelling), thoracic aortic aneurysm disease, and congenital deafness.

17 Mar 2023

What are the associations of COVID-19 policy related economic and schooling disruptions with mental health and sleep in US children?

Researchers investigated whether economic and schooling disruptions associated with COVID-19 mitigation policies and unemployment rates were independently associated with perceived stress, sorrow, and positive stress effect, sleep, and COVID-19-associated worry.

17 Mar 2023

Loss of a beta cell subset might contribute to type 2 diabetes

Multiple types of beta cells produce insulin in the pancreas, helping to balance blood sugar levels. Losing a particularly productive type of beta cell may contribute to the development of diabetes, according to a new study by Weill Cornell Medicine investigators.

17 Mar 2023

Research News and Research

Designer DNA drug could be used to delay paralysis in ALS

Study reveals the underlying mechanism by which TKI cancer drugs cause inflammation

Researchers fabricate first wearable sensor to detect and monitor muscle atrophy

CRISPR-based genome editing restores the vision of mice with retinitis pigmentosa

Is antenatal COVID-19–related stress associated with postpartum maternal mental health and infant outcomes?

Drug combination may reduce the risk of prostate cancer progression, death

Stanford researchers study causes of and treatments for long COVID

How the structural and functional effects of mutations on androgen receptor lead to prostate cancer

Genomic analysis of Ashaninka individuals reveals an unexpected amount of underlying diversity

Computational analysis of large genetic datasets reveals rare disease etiologies

What are the associations of COVID-19 policy related economic and schooling disruptions with mental health and sleep in US children?

Loss of a beta cell subset might contribute to type 2 diabetes

Study suggests a novel strategy to combat multidrug-resistant S. pneumoniae infections

Living well: circumstances and behaviors are equally as important as psychological traits

When mass spectrometry redefines molecular biology and biochemistry – the future of spatial omics

How the science of happiness is helping student mental health

Does vitamin D play an anti-viral role against SARS-CoV-2?

Study confirms the benefit of Paxlovid as an early-stage treatment to prevent COVID-19 hospitalization

What are the top sodium food sources in the United States?

Could ChatGPT revolutionize obstetrics and gynecology?

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