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Promising compound blocks production of beta amyloid peptides in Alzheimer's mouse model

Offering a potential early intervention for Alzheimer's disease (AD), researchers at University of California, San Diego School of Medicine and Cenna Biosciences, Inc. have identified compounds that block the production of beta amyloid peptides in mice.

30 Apr 2015

Novel combination therapy shows promise in mouse models of advanced prostate cancer

Chemotherapy can be very effective against small prostate tumors. Larger prostate tumors, however, accumulate cells that suppress the body's immune response, allowing the cancer to grow despite treatment.

30 Apr 2015

Dr. Philipp Scherer to receive prestigious Banting Medal for Scientific Achievement from ADA

Dr. Philipp Scherer, Director of the Touchstone Center for Diabetes Research at UT Southwestern Medical Center, will receive the prestigious Banting Medal for Scientific Achievement, the highest honor bestowed by the American Diabetes Association.

30 Apr 2015

Study finds that gene therapy can clip out genetic material associated with heart failure

Gene therapy can clip out genetic material linked to heart failure and replace it with the normal gene in human cardiac cells, according to a study led by researchers from the Cardiovascular Research Center at Icahn School of Medicine at Mount Sinai.

30 Apr 2015

Cytokine GM-CSF likely plays important role in MS

Multiple sclerosis (MS) is caused by immune cells that activate a cascade of chemicals in the brain, attacking and degrading the insulation that keeps neuronal signals moving. These chemicals, called cytokines, drive the inflammation in the brain, attracting more immune cells, and causing the debilitating disease marked by loss of neurological function.

30 Apr 2015

Study opens door for new therapeutic approaches to treating patients with melanoma

Weill Cornell Medical College researchers have shown for the first time that a gene previously implicated in blood vessel formation during embryonic development and tumor growth also induces immune suppression during tumor development.

30 Apr 2015

$Bone-marrow-derived MSCs can promote fracture healing$

Bone-marrow-derived MSCs can promote fracture healing

Mesenchymal stem cells (MSCs) have been transplanted to successfully treat a variety of diseases and conditions. The benefit of using MSCs is their ability to self-renew and differentiate into a variety of specialized cell types, such as osteoblasts (cells contributing to bone formation), chondrocytes (cartilage cells), adipocytes (fat cells), myocardiocytes (the muscle cells that make up the cardiac muscle), and neurons (nervous system cells).

30 Apr 2015

Rudolf Jaenisch honored with 2015 March of Dimes Prize in Developmental Biology

Rudolf Jaenisch, MD, who laid the groundwork for the development and use of induced pluripotent stem (iPS) cells - stem cells derived directly from adult tissue -- to potentially treat and cure a variety of human diseases, has received the 20th anniversary March of Dimes Prize in Developmental Biology.

30 Apr 2015

CANCER-ID consortium aims to set up standard procedures for clinical validation of blood-based biomarkers

Blood-based biomarkers such as circulating tumor cells (CTCs), circulating free DNA (cfDNA), circulating tumor DNA (ctDNA) and microRNAs (miRNAs) are potential indicators for the tumor burden of patients living with cancer.

30 Apr 2015

Sangamo BioSciences to present data on ZFP Therapeutic platform at ASGCT meeting

Sangamo BioSciences, Inc. announced that data from clinical, preclinical and research-stage programs focused on the development of ZFP Therapeutics will be presented at the 18th Annual Meeting of the American Society of Gene and Cell Therapy

29 Apr 2015

US Liquid Handling Market estimated to reach $974 million in 2021

The trend of laboratories moving from manual methods to automated workflows is advancing momentum in the uptake of liquid handling instruments in the U.S. Stricter regulations and a growing focus on data precision, efficiency and reproducibility are driving the transition to automation in liquid handling.

29 Apr 2015

UI orthopedics researchers working on injectable, bioactive gel that can repair cartilage damage

Knee injuries are the bane of athletes everywhere, from professionals and college stars to weekend warriors. Current surgical options for repairing damaged cartilage caused by knee injuries are costly, can have complications, and often are not very effective in the long run. Even after surgery, cartilage degeneration can progress leading to painful arthritis.

29 Apr 2015

Link between dDsk2 protein and neurodegenerative diseases identified

Until today, the proteins known as ubiquitin receptors have been associated mainly with protein degradation, a basic cell cleaning process. A new function now described for the protein dDsk2 by the team headed by Ferran Azorín, group leader at the Institute for Research in Biomedicine (IRB Barcelona) and CSIC research professor, links ubiquitin receptors for the first time with the regulation of gene expression.

29 Apr 2015

Researchers discover key mechanism in neural death that causes Parkinson's disease

In studying the molecular biology of brain development, a team of researchers led by Ludwig Stockholm director Thomas Perlmann has discovered how disruption of a developmental mechanism alters the very nerve cells that are most affected in Parkinson's disease.

29 Apr 2015

Scripps Florida scientists uncover surprising new details of potential alzheimer’s treatment

The new study points to promising new directions using a known therapeutic strategy for Alzheimer’s disease—a disorder that will affect nearly 14 million Americans by 2050, according to the Alzheimer’s Association...

29 Apr 2015

New TSRI study points to promising new therapeutic target for Alzheimer's disease

Taking a new approach, scientists from the Florida campus of The Scripps Research Institute (TSRI) have uncovered some surprising details of a group of compounds that have shown significant potential in stimulating the growth of brain cells and memory restoration in animal models that mimic Alzheimer's disease.

29 Apr 2015

McMaster researchers explore how surgeon's experience influences choice of surgery for patients

Researchers at McMaster University (Hamilton, ON) explored whether a surgeon's expertise influences procedural choice. The results of a new study of more than 8000 non-small cell lung cancer (NSCLC) patients undergoing surgical resection by 124 physicians showed that surgeons who perform more surgeries are less likely to perform high-risk pneumonectomies. Christian J. Finley, MD, MPH, will be presenting the results of this research at the 95th AATS Annual Meeting in Seattle, WA on April 28, 2015.

29 Apr 2015

Montefiore and Einstein researchers to present data on obesity, asthma and autism at PAS 2015

Researchers from the Children's Hospital at Montefiore and Albert Einstein College of Medicine will present data from more than 50 studies that explore topics including obesity, asthma and autism at the annual meeting of the Pediatric Academic Societies.

29 Apr 2015

Researchers develop new IVF technique to improve fertility treatment

For couples struggling to conceive the old-fashioned way, in vitro fertilization (IVF) provides an alternate route to starting a family. When eggs are mixed with sperm in test tubes, the fertilized eggs to grow into embryos that can be implanted inside the uterus of a woman who will carry them to term.

29 Apr 2015

Linkam stages used to study the effects of cryopreservation on the quality of Koala spermatozoa samples

Market leaders in temperature controlled microscopy, Linkam Scientific Instruments report on the use of their temperature controlled stages in the study of the effects of cryopreservation of Koala spermatozoa in Australia.

From Linkam Scientific Instruments 28 Apr 2015

B Cell News and Research

Promising compound blocks production of beta amyloid peptides in Alzheimer's mouse model

Novel combination therapy shows promise in mouse models of advanced prostate cancer

Dr. Philipp Scherer to receive prestigious Banting Medal for Scientific Achievement from ADA

Study finds that gene therapy can clip out genetic material associated with heart failure

Cytokine GM-CSF likely plays important role in MS

Study opens door for new therapeutic approaches to treating patients with melanoma

Bone-marrow-derived MSCs can promote fracture healing

Rudolf Jaenisch honored with 2015 March of Dimes Prize in Developmental Biology

CANCER-ID consortium aims to set up standard procedures for clinical validation of blood-based biomarkers

Sangamo BioSciences to present data on ZFP Therapeutic platform at ASGCT meeting

US Liquid Handling Market estimated to reach $974 million in 2021

UI orthopedics researchers working on injectable, bioactive gel that can repair cartilage damage

Link between dDsk2 protein and neurodegenerative diseases identified

Researchers discover key mechanism in neural death that causes Parkinson's disease

Scripps Florida scientists uncover surprising new details of potential alzheimer’s treatment

New TSRI study points to promising new therapeutic target for Alzheimer's disease

McMaster researchers explore how surgeon's experience influences choice of surgery for patients

Montefiore and Einstein researchers to present data on obesity, asthma and autism at PAS 2015

Researchers develop new IVF technique to improve fertility treatment

Linkam stages used to study the effects of cryopreservation on the quality of Koala spermatozoa samples

Industry focus eBook - Cell and gene therapy (2nd edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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