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New single probe method provides PCR-free detection of microRNA linked to liver toxicity

Quanterix Corporation, a company digitizing biomarker analysis with the goal of advancing the science of precision health, and DestiNA Genomics Ltd, a manufacturer of patented reagents for nucleic acid detection, today announced that PLOS ONE has published a proof-of-concept single probe method for detecting microRNA biomarkers associated with liver toxicity.

6 Jul 2017

New, improved microcontact printing technology offers big hope for disease detection

OIST researchers develop a simple printing method to create effective disease detection tools.The field of medicine is always on the lookout for better disease diagnostic tools—simpler, faster, and cheaper technologies to enhance patient treatment and outcomes.

30 Jun 2017

American scientists develop bioorthogonal labeling test to assess sialylated glycans in tumor cells

Glycosylated proteins are often overexpressed in tumor cells and thus could serve as tumor markers, especially those with the interesting molecule sialic acid as their sugar moiety.

28 Jun 2017

New biomarker assay improves detection, assessment of neuroblastoma

Investigators at The Saban Research Institute of Children's Hospital Los Angeles have developed and tested a new biomarker assay for quantifying disease and detecting the presence of neuroblastoma even when standard evaluations yield negative results for the disease.

23 Jun 2017

Penn study points to novel therapeutic strategy for preventing severe tooth decay in toddlers

Though most tooth decay can be blamed on bacteria, such as Streptococcus mutans, the fungus Candida albicans may be a joint culprit in an alarmingly common form of severe tooth decay affecting toddlers known as early childhood caries.

20 Jun 2017

Simple tool based on DNA barcoding technology enables naked-eye authentication of food

Is the food on the shelf really that what is written on the label? Its DNA would give it away, but the DNA barcoding technology, which can be used for this purpose, is labor-intensive.

19 Jun 2017

IDT introduces novel rhAmp technology for accurate, cost-effective SNP analysis

Reflecting its mission to provide innovative solutions to the genomics community, Integrated DNA Technologies introduces its unique rhAmp™ SNP Genotyping System, enabling researchers to make accurate and confident SNP calls both quickly and cost-effectively.

19 Jun 2017

Domainex, Imperial College London expand collaboration to lessen cardiac muscle damage during heart attacks

Domainex Ltd. expands its partnership with Imperial College London, to discover novel therapies that reduce heart muscle damage during heart attacks. The aim is to discover a drug that inhibits the enzyme MAP4K4, which plays a key role in triggering cell death following a heart attack.

19 Jun 2017

New tools can potentially play key role in early diagnosis of systemic sclerosis

The results of two studies presented today at the Annual European Congress of Rheumatology (EULAR) 2017 press conference highlight the use of two new tools, which can potentially play a pivotal role in the early diagnosis of Systemic Sclerosis.

14 Jun 2017

Zika viral load not necessarily linked to pregnancy problems, fetal abnormalities

UCLA-led researchers have found that Zika viral load and the degree of Zika symptoms during pregnancy were not necessarily associated with problems during pregnancy or fetal abnormalities at birth.

13 Jun 2017

New OpenArray system offers simultaneous detection of pathogens in blood samples

The emergence of new pathogens like West Nile Virus, Ebola, Dengue, and Zika, threaten human health on a global scale.

From Thermo Fisher Scientific - Microbiology 13 Jun 2017

Two-pronged algorithm may prove to be accurate tool for predicting response to checkpoint inhibitors

The class of immunotherapies known as checkpoint inhibitors have proven to be a highly effective and advantageous treatment option for many cancer patients, but they don't work well for everyone, and oncologists have no reliable way to determine in advance which patients are likely to respond to these drugs.

7 Jun 2017

Obese people twice as likely to develop influenza despite getting flu shots

Although influenza vaccines are currently the best forms of protection to safeguard people against getting the flu, they are not effective in all cases.

6 Jun 2017

Reliable clinical assay detects Zika virus from semen samples

Research presented at ASM Microbe 2017 by experts at the Fertility and Cryogenics Lab shows a reliable clinical assay that can detect the Zika virus from semen samples.

5 Jun 2017

New genomic sequencing approach could be first step toward blood tests for early cancer detection

In a study of 124 patients with advanced breast, lung, and prostate cancers, a new, high-intensity genomic sequencing approach detected circulating tumor DNA at a high rate.

5 Jun 2017

Genetic sequencing could help direct treatment for 72% of advanced cancer patients

A new analysis finds that nearly three-quarters of 500 patients with advanced cancer could be referred to a potential targeted treatment based on the results of a comprehensive analysis of their tumor's genetic landscape.

2 Jun 2017

UCSB biologists develop new antimicrobial susceptibility test to transform the way antibiotics are tested

When a patient is prescribed the wrong antibiotic to treat a bacterial infection, it's not necessarily the physician who is at fault. The current antibiotic assay -- standardized in 1961 by the World Health Organization and used worldwide -- is potentially flawed.

2 Jun 2017

Researchers gain new insights into factors crucial for STIM1 activation

Triggered by decreases in ER Ca2+ level, conformational changes of the endoplasmic reticulum (ER) luminal domain in STIM1 would switch on its cytoplasmic domain (CT) to engage and gate ORAI channels on plasma membrane, resulting in Ca2+ influx.

1 Jun 2017

Study shows how high-sensitivity assay improves evaluation for chest pain patients

For some time now, patients in Sweden's emergency clinics complaining of chest pain have been evaluated using the "high-sensitivity troponin T" assay. In a large-scale registry study published in the Journal of the American College of Cardiology scientists at Karolinska Institutet show how this more sensitive analytical method has improved evaluation for these patients.

30 May 2017

Scientists create a faster, less labor-intensive test to detect “hidden” HIV

The search to develop a HIV cure has long been overwhelmed by a seemingly simple question: How do physicians find out if somebody is cured? The virus has an ability to lie dormant in immune cells at levels that could not be detected to all, however, the most expensive and time-consuming tests can find the hidden virus.

30 May 2017

Assay News and Research

New single probe method provides PCR-free detection of microRNA linked to liver toxicity

New, improved microcontact printing technology offers big hope for disease detection

American scientists develop bioorthogonal labeling test to assess sialylated glycans in tumor cells

New biomarker assay improves detection, assessment of neuroblastoma

Penn study points to novel therapeutic strategy for preventing severe tooth decay in toddlers

Simple tool based on DNA barcoding technology enables naked-eye authentication of food

IDT introduces novel rhAmp technology for accurate, cost-effective SNP analysis

Domainex, Imperial College London expand collaboration to lessen cardiac muscle damage during heart attacks

New tools can potentially play key role in early diagnosis of systemic sclerosis

Zika viral load not necessarily linked to pregnancy problems, fetal abnormalities

New OpenArray system offers simultaneous detection of pathogens in blood samples

Two-pronged algorithm may prove to be accurate tool for predicting response to checkpoint inhibitors

Obese people twice as likely to develop influenza despite getting flu shots

Reliable clinical assay detects Zika virus from semen samples

New genomic sequencing approach could be first step toward blood tests for early cancer detection

Genetic sequencing could help direct treatment for 72% of advanced cancer patients

UCSB biologists develop new antimicrobial susceptibility test to transform the way antibiotics are tested

Researchers gain new insights into factors crucial for STIM1 activation

Study shows how high-sensitivity assay improves evaluation for chest pain patients

Scientists create a faster, less labor-intensive test to detect “hidden” HIV

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

How Omics Technologies Are Transforming Biological Research and Drug Discovery

How microplastics and bacteria interact to drive antibiotic resistance

Single-cell proteomics: Revealing proteome diversity from cellular heterogeneity to non-canonical biology

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