Bone Marrow News and Research

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Bone Marrow is the soft, sponge-like tissue in the center of most bones. It produces white blood cells, red blood cells, and platelets.

FDA approves Rituxan-corticosteroid combination for Wegener's Granulomatosis and Microscopic Polyangiitis

Genentech, a member of the Roche Group and Biogen Idec announced today that the U.S. Food and Drug Administration (FDA) approved Rituxan® (rituximab), in combination with corticosteroids, as a new medicine for adults with Wegener's Granulomatosis (WG) and Microscopic Polyangiitis (MPA).

20 Apr 2011

Positive interim anemia response data from YM's CYT387 Phase I/II trial in myelofibrosis

YM BioSciences Inc., today announced that updated interim anemia response data were reported for the first 60 patients enrolled in the Phase I/II trial of its JAK1/JAK2 inhibitor, CYT387, for the treatment of myelofibrosis.

19 Apr 2011

Chronic exposure to polluted air can lead to inflammation

Chronic inhalation of polluted air appears to activate a protein that triggers the release of white blood cells, setting off events that lead to widespread inflammation, according to new research in an animal model.

16 Apr 2011

Cytonet initiates clinical trial using liver cell infusion to treat urea cycle disorders in children

International biotechnology firm Cytonet recently launched the first ever clinical trial in the United States using an investigational liver cell infusion to treat urea cycle disorders (UCD) in children. The first patient in the Phase II trial, which will seek to enroll 20 patients in 12 medical centers, is a child with citrullinemia, which is a hereditary UCD. He received six liver cell infusions on six consecutive days at Yale School of Medicine in New Haven, Conn.

15 Apr 2011

Sea squirt study may help solve organ rejection problems in humans

Studies of the small sea squirt may ultimately help solve the problem of rejection of organ and bone marrow transplants in humans, according to scientists at UC Santa Barbara.

15 Apr 2011

Experts suggest Fukushima clean-up workers store blood cells for future use

As Japan still reels with the after effects of the March 11 earthquake and tsunami, and radiation exposure, plant workers are working to control the radiation leakage from the Fukushima Daiichi complex. Experts note that the work there will take years, posing a risk of accidental exposure.

15 Apr 2011

Novel drug holds potential against resistant chronic myeloid leukemia

A study from Tufts Medical Center researchers published today finds that a novel drug shows promise for treating leukemia patients who have few other options because their disease has developed resistance to standard treatment.

12 Apr 2011

UMMC Professor receives American College of Physicians' highest honor

Dr. Joe Files, professor of medicine and director of the Division of Hematology at the University of Mississippi Medical Center, has received his mastership from the American College of Physicians, joining a select group of Mississippi physicians who have received the national organization’s highest recognition.

11 Apr 2011

NCI, ASH, AMEH join to improve care for patients with AML

A workshop being held today will serve as the launch of a unique project that unites the American Society of Hematology, the Agrupaci-n Mexicana para el Estudio de la Hematolog-a, and the National Cancer Institute in pursuit of a common goal: improving the care of patients with acute myeloid leukemia.

11 Apr 2011

Polaris' ADI-PEG 20 exhibits potential against AML, GBM and bladder cancer

Polaris Group announced today that data from preclinical studies suggest ADI-PEG 20, the Company's pegylated arginine deiminase therapeutic, may be effective in treating acute myeloid leukemia (AML), glioblastoma multiforme (GBM) and bladder cancer.

8 Apr 2011

Cenovus donates $1.3 million to Alberta Children's Hospital to combat childhood cancer

Cenovus Energy Inc. is proud to announce that the company has committed $1.3 million to the Alberta Children's Hospital Foundation to help experts at the Alberta Children's Hospital in the fight against childhood cancer.

8 Apr 2011

South Sudan health workers face worst Kala-azar outbreak

South Sudan is facing the worst outbreak of Kala-azar in the past 10 years as health workers from Servant's Heart Relief race against the clock to stop the spread of the deadly disease.

5 Apr 2011

Injection of stem cells may improve effectiveness of cardiac bypass surgery

In a new research study under way at the Methodist DeBakey Heart & Vascular Center, surgeons are adding a patient's own stem cells to the heart during cardiac bypass surgery. The goal of this research study is to determine whether the stem cell infusion will generate new blood vessels and improve heart function more than what is seen through bypass surgery alone.

5 Apr 2011

Lilly presents results of JAK2, Hedgehog inhibitor preclinical cancer studies at 102nd AACR

Eli Lilly and Company announced results today from two preclinical studies of molecules that target genetic mutations and disable specific signaling pathways that can lead to cancer. The studies evaluated two unique molecules – a JAK2 inhibitor and a Hedgehog inhibitor – with results presented during the American Association for Cancer Research (AACR) 102nd Annual Meeting in Orlando, Fla.

5 Apr 2011

Optimer study highlights economic burden of acute and recurrent CDI in hospital patients

Optimer Pharmaceuticals, Inc. announced today the presentation of information from insurance claims and survey databases highlighting the unmet need for targeted therapies to treat subpopulations at high risk of recurrence of Clostridium difficile infection.

4 Apr 2011

Thalidomide provides new hope for patients with difficult to treat liver cancer

Thalidomide has shown potential to be used as the first adjuvant therapy for hepatocellular carcinoma, according to data presented at the International Liver Congress 2011.

2 Apr 2011

NeoStem revenues increase 13% for the year ended December 31, 2010

NeoStem, Inc., an international biopharmaceutical company with operations in the U.S. and China, is today providing unaudited results for 2010 and an update of recent activities.

2 Apr 2011

Merck's VICTRELIS phase III study results against HCV presented at EASL annual meeting

Merck, known as MSD outside of the United States and Canada, announced results from several new data analyses from the pivotal Phase III studies evaluating the addition of its investigational oral protease inhibitor VICTRELIS to peginterferon alfa-2b and ribavirin in adult patients with chronic hepatitis C virus genotype 1 infection.

1 Apr 2011

Texas Children's Hospital and Baylor College of Medicine create Texas Children's Center for Global Health

Texas Children's Hospital and Baylor College of Medicine (BCM) today announced the creation of the Texas Children's Center for Global Health and the appointment of renowned physician-scientist Dr. Russell E. Ware as director.

31 Mar 2011

Master regulators of cholesterol and fat play key role in liver fibrosis development

UCLA researchers have demonstrated that a key regulator of cholesterol and fat metabolism in the liver also plays an important role in the development of liver fibrosis - the build-up of collagen scar tissue that can develop into cirrhosis. Cirrhosis, in turn, is a major cause of premature death and is incurable without a liver transplant.

31 Mar 2011

Bone Marrow News and Research

Further Reading

FDA approves Rituxan-corticosteroid combination for Wegener's Granulomatosis and Microscopic Polyangiitis

Positive interim anemia response data from YM's CYT387 Phase I/II trial in myelofibrosis

Chronic exposure to polluted air can lead to inflammation

Cytonet initiates clinical trial using liver cell infusion to treat urea cycle disorders in children

Sea squirt study may help solve organ rejection problems in humans

Experts suggest Fukushima clean-up workers store blood cells for future use

Novel drug holds potential against resistant chronic myeloid leukemia

UMMC Professor receives American College of Physicians' highest honor

NCI, ASH, AMEH join to improve care for patients with AML

Polaris' ADI-PEG 20 exhibits potential against AML, GBM and bladder cancer

Cenovus donates $1.3 million to Alberta Children's Hospital to combat childhood cancer

South Sudan health workers face worst Kala-azar outbreak

Injection of stem cells may improve effectiveness of cardiac bypass surgery

Lilly presents results of JAK2, Hedgehog inhibitor preclinical cancer studies at 102nd AACR

Optimer study highlights economic burden of acute and recurrent CDI in hospital patients

Thalidomide provides new hope for patients with difficult to treat liver cancer

NeoStem revenues increase 13% for the year ended December 31, 2010

Merck's VICTRELIS phase III study results against HCV presented at EASL annual meeting

Texas Children's Hospital and Baylor College of Medicine create Texas Children's Center for Global Health

Master regulators of cholesterol and fat play key role in liver fibrosis development

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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