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Redefining cardiovascular medicine through the lens of sncRNAs

In a transformative review, small noncoding RNAs (sncRNAs) have emerged as pivotal regulators in the complex landscape of cardiovascular diseases.

20 Apr 2025

Targeting PGM3 offers new hope against deadly brain tumor

Researchers have found that targeting an enzyme called PGM3 can help stop the growth of glioblastoma, the most dangerous type of brain tumor.

18 Apr 2025

Medicare claims for genetic cancer tests face growing rejection rates

Both the use of next-generation sequencing (NGS) testing for cancer and the rate of claim denials for such testing increased between 2016 and 2021, despite implementation of a recent Medicare national coverage determination that established coverage standards for NGS testing.

18 Apr 2025

Evaluating hydronidone for the treatment of chronic hepatitis B-associated liver fibrosis

Liver fibrosis is a key process in the progression of chronic liver diseases. However, there are currently no drugs specifically designed to treat liver fibrosis.

18 Apr 2025

Study examines how COX-2 regulates ferroptosis in chronic liver injury

Ferroptosis plays an essential role in chronic liver diseases, and cyclooxygenase-2 (COX-2) affects liver fibrosis through multiple mechanisms. +

18 Apr 2025

Covid worsened shortages of doctors and nurses. Five years on, rural hospitals still struggle.

Even by rural hospital standards, Keokuk County Hospital and Clinics in southeastern Iowa is small.

18 Apr 2025

Why “eat 1 more” boosts fruit and vegetable intake more than “5 a day”

Setting specific goals, especially achievable ones like "Eat 1 more", significantly increased fruit and vegetable intake in both controlled and real-world environments. However, whether the goal was framed around current or future benefits had little impact on consumption.

18 Apr 2025

Key enzyme found to influence immune aging and B cell production

Our immune systems weaken as we get older, making fewer cells that fight infection and help us recover from illness and injury. Scientists aren't completely sure why. They may have a better idea now, however, thanks to a new study in GeroScience.

17 Apr 2025

Rice University hosts global health innovation competition

At the Rice360 Institute for Global Health Technologies' 15th annual Undergraduate Design Competition, the future of global health innovation was on full display.

17 Apr 2025

Researchers identify gene targets that may protect against Alzheimer’s

A study published in the American Journal of Human Genetics by researchers at Baylor College of Medicine and the Jan and Dan Duncan Neurological Research Institute (Duncan NRI) at Texas Children's Hospital provides solutions to the pressing need to identify factors that influence Alzheimer's disease (AD) risk or resistance while providing an avenue to explore potential biological markers and therapeutic targets.

17 Apr 2025

Researchers use algorithm to pinpoint disease risk mutations in noncoding DNA

Researchers from Children's Hospital of Philadelphia (CHOP) and the Perelman School of Medicine at the University of Pennsylvania (Penn Medicine) have successfully employed an algorithm to identify potential mutations which increase disease risk in the noncoding regions our DNA, which make up the vast majority of the human genome.

17 Apr 2025

Hydroxyurea shows long-term benefits for children with sickle cell disease

Hydroxyurea remains effective long-term in reducing emergency department visits and hospital days for children living with sickle cell disease (SCD), according to new research published in Blood Advances.

17 Apr 2025

Experimental bird flu vaccine offers strong protection in preclinical trials

A vaccine under development at the University at Buffalo has demonstrated complete protection in mice against a deadly variant of the virus that causes bird flu.

17 Apr 2025

Nontraditional risk factors linked to stroke in adults under 50

Adults younger than 50 years of age had more than double the risk of having a stroke from migraine or other nontraditional stroke risk factors rather than traditional risks such as high blood pressure, according to research published today in Stroke, the peer-reviewed scientific journal of the American Stroke Association, a division of the American Heart Association.

17 Apr 2025

Beyond Ivy League, RFK Jr.’s NIH slashed science funding across states that backed Trump

The National Institutes of Health's sweeping cuts of grants that fund scientific research are inflicting pain almost universally across the U.S., including in most states that backed President Donald Trump in the 2024 election.

17 Apr 2025

Seasonal air pollution found to undermine IVF success

Exposure to fine particulate matter during fertility treatment windows—especially in winter—negatively impacts pregnancy and live birth rates

17 Apr 2025

Mount Sinai Fuster Heart Hospital earns national recognition for patient care excellence

The Mount Sinai Fuster Heart Hospital's cardiology faculty practice has received the 2024 Human Experience Pinnacle of Excellence Award from Press Ganey, one of the nation's leading patient experience organizations.

16 Apr 2025

Metabolic syndrome found to increase risk of breast cancer recurrence and death

New research to be presented at this year's European Congress on Obesity (ECO 2025, Malaga, Spain, 11-14 May) and published in The Journal of Internal Medicine shows that, in survivors of breast cancer, having an unhealthy metabolic profile or so called 'metabolic syndrome' increases the risk of breast cancer recurrence by 69%, and subsequent breast cancer mortality by 83%.

16 Apr 2025

FOXR2 activation found in multiple pediatric brain tumor types

Physicians classify brain tumors and determine treatment options, in part, by the genes they express. According to World Health Organization standards, the abnormal activation of oncogene FOXR2 only occurs in central nervous system (CNS) neuroblastoma, but that may not be true.

16 Apr 2025

Transcranial magnetic stimulation and speech therapy boost language skills in stroke patients

Lucy Mulloor woke up one morning and realized something was terribly wrong. The 45-year-old single-mom could hear her two daughters in the kitchen but couldn't call out to them.

16 Apr 2025