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Antioxidant compound proves effective in kidney ischemia-reperfusion treatment

Russian researchers from the Moscow Institute of Physics and Technology, the Institute of Cell Biophysics, and elsewhere have shown an antioxidant compound known as peroxiredoxin to be effective in treating kidney injury in mice.

9 Sep 2019

Message transfer between mammal neurons regulated by 'clamp'

A fundamental question in nerve biology brings to mind a race car at the starting line: The engine is revving, but the brake is on. The system is ready to go, but under tight control.

9 Sep 2019

$15 million grant funds new effort to develop universal vaccine for strep throat infections

CARB-X, an international non-profit partnership of private, academic and government institutions, has awarded SutroVax, Inc., a Northern California-based biopharmaceutical company, with an award of up to $15 million to develop a universal vaccine for Group A Streptococcus, the bacteria that causes pharyngitis or strep throat.

4 Sep 2019

Bacterial endotoxin testing now offered by Perfectus Biomed

Endotoxins are toxins present within a bacterial cell wall that are released when a cell disintegrates. They are lipopolysaccharides (LPS) and are found within the outer membrane of the cell wall of Gram-negative bacteria. Endotoxins often consist of lipid A, a core oligosaccharide and the O-specific polysaccharide.

From Perfectus Biomed 3 Sep 2019

DNA methylation closely linked to telomere length

Aging is associated with multiple disease conditions. Recently it has been found that many of these illnesses are linked to the length of the telomeres at the ends of every chromosome. Telomere length (TL) is affected by both genetic and epigenetic contributions.

2 Sep 2019

Researchers illuminate mysterious aspect of mitochondrial metabolism using a tiny thermometer

Armed with a tiny new thermometer probe that can quickly measure temperature inside of a cell, University of Illinois researchers have illuminated a mysterious aspect of metabolism: heat generation.

30 Aug 2019

New cellular processes controlling the formation of lymphatic valves found

Lymphedema, resulting from a damaged lymphatic system, can be a debilitating disease in which excess protein-rich fluid (lymph) collects in soft tissues and causes swelling -- most often in the arms or legs.

28 Aug 2019

Researchers reveal skin cream’s true molecular structure

Anyone who has gone through the stress and discomfort of raw, irritated skin knows the relief that comes with slathering on a creamy lotion.

27 Aug 2019

"Australian" genetic mutation provides clues to Alzheimer’s mechanism

In an astonishing new breakthrough in Alzheimer’s research, the molecular basis of early-onset Alzheimer’s disease (AD) and age-linked AD has been identified by looking at one type of genetic mutation.

26 Aug 2019

Researchers target cancer's protective barrier

Cancer cells are notorious for their camouflage work, which enables them to escape immune targeting. Now scientists are learning how to strip away the disguise and allow the immune system to do its work, by targeting cells called myeloid-derived suppressor cells (MDSCs) that shield the tumor. This would also enhance the effectiveness of newer cancer immunotherapies like Chimeric-Antigen Receptor T cell (CAR-T).

26 Aug 2019

Researchers create synthetic biologic system to deliver medicine, treat wounds for soldiers

For the first time, scientists built a synthetic biologic system with compartments like real cells. This Army project at the University of Massachusetts Amherst could lead to materials that provide new avenues to deliver medicine, treat wounds and purify water for Soldiers.

23 Aug 2019

Researchers take important step towards preventing cancer metastasis

Researchers at the Paul Scherrer Institute, together with colleagues from the pharmaceutical company F. Hoffmann-La Roche AG, have taken an important step towards the development of an agent against the metastasis of certain cancers.

23 Aug 2019

New study reveals mechanism of ultraviolet-induced skin breakdown

The sunscreen industry has been plugging the use of various sun-protective creams for decades, ever since researchers found that certain skin cancers, including malignant melanoma, were due to sunlight-induced skin damage.

22 Aug 2019

Ludwig study uncovers novel vulnerability in MYC-driven cancers

A Ludwig Cancer Research study has uncovered a novel vulnerability in tumors that are driven by a common cancer gene known as MYC. Such cancers, it found, are highly dependent on the cell's machinery for making fats and other lipids.

22 Aug 2019

Protein plays important roles in intracellular membrane trafficking in the brain

Our bodies couldn’t operate without the central nervous system - a complex network that coordinates our actions, reflexes, and sensations. Each neuron in your brain has one long cable that snakes away from the main part of the cell.

20 Aug 2019

Using principles of mechanics and physics to identify state of individual cells

Researchers at the NYU Tandon School of Engineering have discovered a new way to identify the state of individual cells by bringing principles of mechanical engineering and physics to bear on processes that are now well understood at the macro level, but not yet at the cellular level: how stressors such as injury and disease force an organism into a new level of equilibrium -- a biological process of finding a "new normal" called allostasis.

20 Aug 2019

Researchers develop new gene editing system that could be used for anticancer immunotherapy

Dr. Mihue Jang and her group at the Center for Theragnosis of the Korea Institute of Science and Technology announced that they have developed a new gene-editing system that could be used for anticancer immunotherapy through the simultaneous suppression of proteins that interfere with the immune system expressed on the surface of lymphoma cells and activation of cytotoxic T lymphocyte, based on the results of joint research conducted with Prof. Seokmann Hong and his group at Sejong University.

20 Aug 2019

Chemists develop new approach based on graphene nanoflakes for drug delivery

Chemists funded by the SNSF have created a new compound for flexible drug delivery that specifically targets prostate cancer cells. Incorporating four different molecules, the compound prevents tumor cells from multiplying, can be detected by medical imaging and has staying power in the bloodstream.

19 Aug 2019

Scientists find a potent weapon against antibiotic resistance

Antibiotic resistance is a big threat to global health, and a growing number of infections are now becoming harder to treat. The usual treatments, like antibiotics used to treat them, becomes less effective. Now, a team of researchers may have found a potent weapon against antibiotic-resistant bacteria, which can help treat persistent infections.

15 Aug 2019

Powerful weapon discovered to fight antibiotic resistance in Staphylococcus aureus

Staphylococcus aureus bacteria are a major cause of serious infections that often persist despite antibiotic treatment, but scientists at the UNC School of Medicine have now discovered a way to make these bacteria much more susceptible to some common antibiotics.

14 Aug 2019