Protein News and Research

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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

Health Canada approves SPRYCEL as first-line treatment for life-threatening blood cancer

Canadians newly diagnosed with a life-threatening blood cancer, chronic myeloid leukemia (CML) in chronic phase, now have a new treatment option available to them. Health Canada has granted a notice of compliance with conditions for SPRYCEL (dasatinib) as first-line treatment in patients with chronic phase CML.

22 Jul 2011

Scientists identify bacterial attack pathway

When competing for food and resources, bacteria employ elaborate strategies to keep rival cells at bay. Scientists have now identified a pathway that allows disease-causing bacteria to attack other bacterial cells by breaking down their cell wall.

22 Jul 2011

Insight into Fragile X Syndrome and autism

Researchers now have a much clearer understanding of how mutations in a single gene can produce the complex cognitive deficits characteristic of Fragile X Syndrome, the most common inherited form of intellectual disability.

22 Jul 2011

Enrollment begins in Repligen's RG1068 pilot study to improve detection, staging of pancreatic cancer

Repligen Corporation today announced that the first patient has been enrolled in a pilot study to evaluate the ability of RG1068 to improve detection and characterization of pancreatic cancer in combination with contrast-enhanced magnetic resonance imaging (MRI) and computed tomography.

22 Jul 2011

Bristol-Myers Squibb signs definitive agreement to acquire Amira Pharmaceuticals

Bristol-Myers Squibb Company and Amira Pharmaceuticals, Inc., announced today that the companies have signed a definitive agreement under which Bristol-Myers Squibb will acquire privately held Amira Pharmaceuticals, a small-molecule pharmaceutical company focused on the discovery and early development of new drugs to treat inflammatory and fibrotic diseases.

22 Jul 2011

Australian anti-cancer company completes $2.6 million placement

Australian monoclonal antibody company, Immune System Therapeutics Limited (IST), today said it completed a private placement to raise $2 million from new and existing private and institutional investors in Australia. Investors have agreed to purchase 5,200,000 shares in the company at a price of $0.50 cents per share resulting in gross proceeds of $2.6 million.

21 Jul 2011

Isis commences ISIS-PTP1BRx Phase 1 study in type 2 diabetes

Isis Pharmaceuticals, Inc. announced today that it has initiated a Phase 1 clinical study for ISIS-PTP1BRx, an antisense drug for the treatment of type 2 diabetes targeting protein tyrosine phosphatase-1B, PTP-1B.

21 Jul 2011

Researchers discover novel combination of two mutations in a patient with ADHD

Often enough, in science as in life, unexpected knowledge has a personal impact. Researchers seeking rare gene variants in just a few individuals with attention-deficit hyperactivity disorder (ADHD) discovered that one patient had a novel combination of two mutations.

21 Jul 2011

New strategy for improving development of induced pluripotent stem cells

University of Minnesota Medical School researchers have developed a new strategy to improve the development of induced pluripotent stem cells.

21 Jul 2011

Oxford Nanopore inaugurates new informatics outstation in Cambridge, UK

Oxford Nanopore Technologies, Ltd announces the expansion of its Oxford headquarters and the opening of a new Oxford Nanopore informatics outstation in Cambridge, UK.

From Oxford Nanopore Technologies 21 Jul 2011

Experts present new research at 2011 Alzheimer's Association ICAD

Experts from the Center of Excellence on Brain Aging at NYU Langone Medical Center will present new research at the 2011 Alzheimer's Association International Conference on Alzheimer's disease to be held in Paris, France from July 16 - 21.

21 Jul 2011

Lonza, Cellectis reach milestone in development of newly bioengineered cell line

Cellectis bioresearch, the genome customization specialist and a commercial subsidiary of Cellectis, and Lonza, a world leader in biotechnology production, announce today that they have reached a significant milestone in the development of a newly bioengineered cell line.

21 Jul 2011

Key finding sheds new light on common bleeding disorders

A simple cut to the skin unleashes a complex cascade of chemistry to stem the flow of blood. Now, scientists at Washington University School of Medicine in St. Louis have used evolutionary clues to reveal how a key clotting protein assembles. The finding sheds new light on common bleeding disorders.

21 Jul 2011

Localized one-time gene therapy might effectively protect against atherosclerosis

A one-dose method for delivering gene therapy into an arterial wall effectively protects the artery from developing atherosclerosis despite ongoing high blood cholesterol.

21 Jul 2011

Receptor GPR56 could have a critical role in cancer progression

Melanoma is devastating on many fronts: rates are rising dramatically among young people, it is deadly if not caught early, and from a biological standpoint, the disease tends to adapt to even the most modern therapies, known as VEGF inhibitors.

21 Jul 2011

Artegraft BCA superior to cuffed ePTFE for hemodialysis access

Artegraft, Inc. announces that a three-year prospective, randomized clinical study published in the June 2011 issue of the Journal of Vascular Surgery confirms the superiority of Artegraft Bovine Carotid Artery vascular grafts (BCA) to cuffed ePTFE grafts.

21 Jul 2011

Inherited forms of Alzheimer's could be detected long before memory problems develop

Inherited forms of Alzheimer's disease may be detectable as many as 20 years before problems with memory and thinking develop, scientists will report July 20, 2011, at the Alzheimer's Association International Conference on Alzheimer's Disease in Paris.

21 Jul 2011

Researchers influence activity of nerve cells with laser light

Unlike conventional methods, with the so-called optogenetics, the researchers are able to target one cell type. "We are now going to use this method to find out exactly what goes wrong in the nerve cells in movement disorders such as ataxias", said Prof. Dr. Stefan Herlitze.

21 Jul 2011

Researchers identify IDOL protein as potential new target for lowering LDL cholesterol

High levels of 'bad' cholesterol (LDL cholesterol) are a risk factor for developing atherosclerotic cardiovascular disease (ASCVD) - a disease of the major arterial blood vessels that is one of the major causes of heart attack and stroke.

21 Jul 2011

Intense visual stimulation renders nerve cells more receptive to subsequent learning

Dr. Ed Ruthazer is a mapmaker but, his landscape is the developing brain - specifically the neuronal circuitry, which is the network of connections between nerve cells. His research at The Montreal Neurological Institute and Hospital - The Neuro at McGill University, reveals the brain as a dynamic landscape where connections between nerves are plastic, changing and adapting to the demands of the environment.

21 Jul 2011

Protein News and Research

Further Reading

Health Canada approves SPRYCEL as first-line treatment for life-threatening blood cancer

Scientists identify bacterial attack pathway

Insight into Fragile X Syndrome and autism

Enrollment begins in Repligen's RG1068 pilot study to improve detection, staging of pancreatic cancer

Bristol-Myers Squibb signs definitive agreement to acquire Amira Pharmaceuticals

Australian anti-cancer company completes $2.6 million placement

Isis commences ISIS-PTP1BRx Phase 1 study in type 2 diabetes

Researchers discover novel combination of two mutations in a patient with ADHD

New strategy for improving development of induced pluripotent stem cells

Oxford Nanopore inaugurates new informatics outstation in Cambridge, UK

Experts present new research at 2011 Alzheimer's Association ICAD

Lonza, Cellectis reach milestone in development of newly bioengineered cell line

Key finding sheds new light on common bleeding disorders

Localized one-time gene therapy might effectively protect against atherosclerosis

Receptor GPR56 could have a critical role in cancer progression

Artegraft BCA superior to cuffed ePTFE for hemodialysis access

Inherited forms of Alzheimer's could be detected long before memory problems develop

Researchers influence activity of nerve cells with laser light

Researchers identify IDOL protein as potential new target for lowering LDL cholesterol

Intense visual stimulation renders nerve cells more receptive to subsequent learning

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