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Connection between mitochondrial metabolite and activation of inflammatory response revealed

A new study shows for the first time a connection between a mitochondrial metabolite and the activation of an inflammatory response.

8 Mar 2023

Novel molecular mechanism responsible for common form of acquired hydrocephalus discovered

Mass General researchers have discovered a novel molecular mechanism responsible for the most common forms of acquired hydrocephalus, potentially opening the door to the first-ever nonsurgical treatment for a life-threatening disease that affects about a million Americans.

8 Mar 2023

Pilot trial tests nasal monoclonal antibody treatment for COVID-19

A pilot trial by investigators from Brigham and Women's Hospital, a founding member of the Mass General Brigham healthcare system, tested the nasal administration of the drug Foralumab, an anti-CD3 monoclonal antibody.

8 Mar 2023

Study shows correlations between symptoms of long COVID and physical inactivity

The link between symptoms of COVID-19 and physical inactivity is increasingly evident.

8 Mar 2023

Using tissue-embedded nanoelectronic devices to monitor the functional maturation of cardiomyocytes

Research in animal models has demonstrated that stem-cell derived heart tissues have promising potential for therapeutic applications to treat cardiac disease. But before such therapies are viable and safe for use in humans, scientists must first precisely understand on the cellular and molecular levels which factors are necessary for implanted stem-cell derived heart cells to properly grow and integrate in three dimensions within surrounding tissue.

8 Mar 2023

Detection and targeting of splicing deregulation reveal a potential strategy for pAML therapy

Pediatric acute myeloid leukemia or pAML is a childhood blood cancer, one that has proved confounding to clinicians and researchers, with a high relapse rate and relatively few identified genetic mutations (compared to the adult version) that might explain its cause.

8 Mar 2023

Cedars-Sinai study reveals new insights into the effects of hormonal treatment for transgender men

New insights into the effects of a hormonal treatment for transgender men, discovered by Cedars-Sinai investigators, could have implications for the treatment of breast cancer.

8 Mar 2023

Many hospitals struggle to successfully implement enhanced recovery programs for surgery

Enhanced recovery programs (ERPs) provide hospitals with the highest-quality resources to improve patient care for surgery, but many hospitals still struggle to successfully implement these programs and may need more structured resources to boost compliance rates, according to findings published in the Journal of the American College of Surgeons.

8 Mar 2023

COVID-19 patients at increased risk of developing gastrointestinal disorders

People who have had COVID-19 are at increased risk of developing gastrointestinal (GI) disorders within a year after infection compared with people who haven't been infected, according to an analysis of federal health data by researchers at Washington University School of Medicine in St. Louis and the Veterans Affairs St. Louis Health Care system.

8 Mar 2023

Racism contributes to disproportionate newborn drug testing

If a newborn tests positive for certain drugs after birth, mandated reporters in many states – including health care professionals and social workers – are required to report it to Child Protective Services.

8 Mar 2023

University of Utah and Tikkunlev partner to bring heart failure gene therapy innovation to the clinic

The University of Utah, one of the nation's leading research universities, and TikkunLev Therapeutics, a gene therapy company, have announced a new partnership to accelerate an innovative heart-failure gene therapy.

8 Mar 2023

$Male geriatric patients at greater risk of skull fractures from falls than females$

Male geriatric patients at greater risk of skull fractures from falls than females

Each year, more than 3 million people ages 65 and older are treated in emergency departments for fall injuries. Head trauma is the leading cause of serious injury with skull fractures being reported as a serious outcome.

8 Mar 2023

Study identifies a potential new treatment approach for acute myeloid leukemia

A team of researchers has discovered a potential therapeutic that can synergize with existing drugs to more effectively kill certain leukemia cells.

8 Mar 2023

Discovery could lead to effective treatments for acute alcohol intoxication

A shot of a liver-produced hormone called FGF21 sobered up mice that had passed out from alcohol, allowing them to regain consciousness and coordination much faster than those that didn't receive this treatment, UT Southwestern researchers report in a new study.

8 Mar 2023

Prevalence of dementia in India may be higher than previous estimates, study reveals

Dementia in India may be higher than previous estimates have suggested and could be more in line with prevalence rates for countries such as the United States and the United Kingdom, according to a new collaborative study by researchers from the University of Surrey, University of Southern California, University of Michigan, and All India Institute of Medical Sciences.

8 Mar 2023

Research News and Research

Connection between mitochondrial metabolite and activation of inflammatory response revealed

Novel molecular mechanism responsible for common form of acquired hydrocephalus discovered

Pilot trial tests nasal monoclonal antibody treatment for COVID-19

Study shows correlations between symptoms of long COVID and physical inactivity

Using tissue-embedded nanoelectronic devices to monitor the functional maturation of cardiomyocytes

Detection and targeting of splicing deregulation reveal a potential strategy for pAML therapy

Cedars-Sinai study reveals new insights into the effects of hormonal treatment for transgender men

Many hospitals struggle to successfully implement enhanced recovery programs for surgery

COVID-19 patients at increased risk of developing gastrointestinal disorders

Racism contributes to disproportionate newborn drug testing

University of Utah and Tikkunlev partner to bring heart failure gene therapy innovation to the clinic

Male geriatric patients at greater risk of skull fractures from falls than females

Study identifies a potential new treatment approach for acute myeloid leukemia

Discovery could lead to effective treatments for acute alcohol intoxication

Prevalence of dementia in India may be higher than previous estimates, study reveals

Elevated blood pressure linked to worsening cardiac damage during adolescence

Novel culture system for effectively growing large numbers of blood stem cells in the lab

Dementia the strongest risk factor for infection with COVID-19 in older people

Poor sleep associated with different durations of compromised cardiovascular health

Increased prevalence of overweight and obesity among Swedish children during the pandemic

eBook: Advancing neurodegenerative research with iPSC-derived microglia models eBook

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Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

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