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Trial results show routine oral cholera vaccination programme protects people living in endemic regions

An oral cholera vaccine given as part of routine health services is safe and protects against severe cholera in children and adults in urban Bangladesh where the disease is endemic, according to the first real-life trial of this vaccine published in The Lancet.

10 Jul 2015

Vanderbilt investigators develop potential antibody treatments against chikungunya

In late 2013 the Caribbean had its first case of the mosquito-borne chikungunya virus. Today there have been almost 1.2 million cases in 44 countries or territories, including 177 cases in 31 U.S. States. Vanderbilt University Medical Center's James Crowe, M.D., Ann Scott Carell Professor and director of the Vanderbilt Vaccine Center, and his team are reporting the first large panel of antibody treatments against this disease in the current issue of Cell Host and Microbe.

9 Jul 2015

NIH-sponsored clinical trial evaluates new investigational vaccine against West Nile Virus infection

A clinical trial of a new investigational vaccine designed to protect against West Nile Virus infection will be sponsored by the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health.

7 Jul 2015

Research finding could lead to first effective therapies, vaccines against dengue virus

Researchers at Vanderbilt University and the National University of Singapore have determined the structure of a human monoclonal antibody which, in an animal model, strongly neutralizes a type of the potentially lethal dengue virus.

3 Jul 2015

Researchers discover link between acute liver failure and specific gene mutations in young children

Acute liver failure is a rare yet life-threatening disease for young children. It often occurs extremely rapidly, for example, when a child has a fever. Yet in around 50 percent of cases it is unclear as to why this happens. Now, a team of researchers working on an international research project headed by Technische Universität München, the Helmholtz Zentrum Munich and Heidelberg University Hospital have discovered a link between the disease and mutations in a specific gene.

3 Jul 2015

Researchers establish link between NBAS gene and acute liver failure

Acute liver failure is a rare yet life-threatening disease for young children. It often occurs extremely rapidly, for example, when a child has a fever. Yet in around 50 percent of cases it is unclear as to why this happens. Now, a team of researchers working on an international research project headed by Technische Universität München (TUM), the Helmholtz Zentrum Munich and Heidelberg University Hospital have discovered a link between the disease and mutations in a specific gene.

2 Jul 2015

Extreme heat and precipitation events linked to increased risk of Salmonella infections

Extreme heat and precipitation events, which are expected to increase in frequency and intensity due to climate change, are associated with increased risk of Salmonella infections, according to a study led by researchers from the University of Maryland School of Public Health.

2 Jul 2015

Dengue and chikungunya-carrying mosquitoes spreading to new areas, warn scientists

Scientists behind the first global distribution maps of two species of dengue and chikungunya-carrying mosquitoes warn they are spreading to new areas where they could cause disease.

1 Jul 2015

TSRI-led study identifies new immune molecules that protect against Marburg virus

A new study led by scientists at The Scripps Research Institute identifies new immune molecules that protect against deadly Marburg virus, a relative of Ebola virus. The research provides ingredients needed to develop treatments for future Marburg outbreaks.

30 Jun 2015

Ron Simon & Associates files salmonella lawsuit against restaurant located in North Carolina

Today the national food safety law firm of Ron Simon & Associates, along with local counsel Janet, Jenner & Suggs, filed a lawsuit stemming from salmonella-contaminated food served by the Tarheel Q located in North Carolina on U.S. 64 West in Lexington.

26 Jun 2015

New study reveals key part of Ebola virus life cycle at higher resolution than ever before

A new study led by scientists at The Scripps Research Institute (TSRI) reveals a key part of the Ebola virus life cycle at a higher resolution than ever before. The research sheds light on how Ebola virus assembles—and how researchers might stop the often-fatal infection.

26 Jun 2015

Artificial blood technology may help fight disease-transmitting mosquitoes in resource-limited areas

A "nuisance" is probably one of the nicest things people call mosquitoes. Mosquitoes have been called the deadliest animal on the planet, because of the diseases they spread.

26 Jun 2015

Rising number of malaria deaths likely to exceed total number of Ebola deaths

Around 74000 fewer malaria cases than expected were seen at health facilities in Guinea in 2014 compared with pre-Ebola years, new research published in The Lancet Infectious Diseases journal has found.

25 Jun 2015

Purdue University-led study could lead to better treatments for people infected with MERS virus

A Purdue University-led team of researchers studying the Middle East Respiratory Syndrome, or MERS, have found molecules that shut down the activity of an essential enzyme in the virus and could lead the way to better treatments for those infected.

23 Jun 2015

New research could help reverse side effects of acetaminophen overdose

New research could help reverse deadly side effects caused by excessive doses of the drug acetaminophen, the major ingredient in Tylenol and many other over-the-counter and prescription medicines.

23 Jun 2015

$Phase 3 study shows Vectibix meets primary endpoint in patients with chemorefractory wild-type KRAS mCRC$

Phase 3 study shows Vectibix meets primary endpoint in patients with chemorefractory wild-type KRAS mCRC

Amgen today announced that a Phase 3 study evaluating Vectibix (panitumumab) and best supportive care (BSC) met its primary endpoint, demonstrating a statistically significant improvement in overall survival (OS) in patients with chemorefractory wild-type KRAS (exon 2) metastatic colorectal cancer (mCRC) compared to those patients treated with BSC alone.

19 Jun 2015

Study finds that Amazon river boats provide first-class ride for dengue mosquitoes

The urban mosquito that carries the dengue fever virus is hitching rides on river boats connecting the Amazonian town of Iquitos, Peru, with rural areas.

17 Jun 2015

Novartis presents positive Phase III results of Farydak therapy at EHA

Novartis today presented results from a pivotal Phase III clinical trial exploratory subgroup analysis showing a 7.8-month improvement in median progression-free survival when using Farydak in combination with bortezomib and dexamethasone in patients with relapsed or relapsed and refractory multiple myeloma who had received two or more prior regimens, including bortezomib and an immunomodulatory agent.

16 Jun 2015

NSAIDs significantly inhibit ovulation in women with mild musculoskeletal pain

The results of a study presented today at the European League Against Rheumatism Annual Congress (EULAR 2015) show that diclofenac, naproxen and etoricoxib significantly inhibit ovulation in women with mild musculoskeletal pain. Of the women receiving NSAIDs, only 6.3 percent (diclofenac), 25 percent (naproxen) and 27.3 percent (etoricoxib) ovulated, compared with 100 percent of the control group.

12 Jun 2015

BRIM, Janssen announce strategic collaboration to develop effective treatment for dengue

BRIM Biotechnology, Inc., announced today that it has entered a Collaboration, Option and License Agreement with Janssen Pharmaceutica N.V., one of the Janssen Pharmaceutical Companies of Johnson & Johnson.

11 Jun 2015

Fever News and Research

Trial results show routine oral cholera vaccination programme protects people living in endemic regions

Vanderbilt investigators develop potential antibody treatments against chikungunya

NIH-sponsored clinical trial evaluates new investigational vaccine against West Nile Virus infection

Research finding could lead to first effective therapies, vaccines against dengue virus

Researchers discover link between acute liver failure and specific gene mutations in young children

Researchers establish link between NBAS gene and acute liver failure

Extreme heat and precipitation events linked to increased risk of Salmonella infections

Dengue and chikungunya-carrying mosquitoes spreading to new areas, warn scientists

TSRI-led study identifies new immune molecules that protect against Marburg virus

Ron Simon & Associates files salmonella lawsuit against restaurant located in North Carolina

New study reveals key part of Ebola virus life cycle at higher resolution than ever before

Artificial blood technology may help fight disease-transmitting mosquitoes in resource-limited areas

Rising number of malaria deaths likely to exceed total number of Ebola deaths

Purdue University-led study could lead to better treatments for people infected with MERS virus

New research could help reverse side effects of acetaminophen overdose

Phase 3 study shows Vectibix meets primary endpoint in patients with chemorefractory wild-type KRAS mCRC

Study finds that Amazon river boats provide first-class ride for dengue mosquitoes

Novartis presents positive Phase III results of Farydak therapy at EHA

NSAIDs significantly inhibit ovulation in women with mild musculoskeletal pain

BRIM, Janssen announce strategic collaboration to develop effective treatment for dengue

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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