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Investigational drug for treatment of sickle cell disease shows early promise in clinical trials

An investigational drug for the treatment of sickle cell disease is showing early promise in clinical trials for impacting biomarkers of the disease in patients, reported UConn School of Medicine researchers at the European Hematology Association Congress in Amsterdam this week.

20 Jun 2019

Study reveals potential consequences of limiting ovarian cancer surgery to high-volume hospitals

Limiting ovarian cancer surgery to high-volume hospitals could improve survival but may also reduce access for many rural and underserved patients, a new study from researchers at Columbia University Vagelos College of Physicians and Surgeons has found.

20 Jun 2019

Research findings lead to new clinical trial for people with myelofibrosis

Researchers at Huntsman Cancer Institute at the University of Utah (U of U) discovered in laboratory studies that an experimental drug called selinexor may block a crucial survival pathway exploited by myelofibrosis cells.

20 Jun 2019

New type of treatment for osteoarthritis shows promise for use in humans

A new type of treatment for osteoarthritis, currently in canine clinical trials, shows promise for eventual use in humans.

20 Jun 2019

Dangerous brain parasite invades host cell, maintains steady nutrient supply

A team of researchers has found that a dangerous type of parasite that affects the brain, maintains a stable supply of essential nutrients as it replicates in the host cell. In an unexpected turn of events, the body itself delivers food to the harmful predator.

20 Jun 2019

Study: Melanin-concentrating hormone neurons in hypothalamus increase REM sleep

Every night while sleeping, we cycle between two very different states of sleep. Upon falling asleep, we enter non-rapid eye movement sleep where our breathing is slow and regular and movement of our limbs or eyes are minimal.

20 Jun 2019

Researcher employs people who inject drugs to study factors influencing acquisition of HIV

In recent years, the HIV infection rate in Estonia has continued to be around 200 new cases each year, which is still one of the highest incidence rates per 100,000 inhabitants in Europe.

20 Jun 2019

Eyes hold clues to effective treatment of severe autism, study shows

Vocabulary tests for individuals with the severest forms of autism spectrum disorder, or ASD, are notoriously inaccurate. They commonly ask the test-taker to point to an illustration after hearing a spoken word, measuring the ability to understand and perform a task as much as word knowledge.

20 Jun 2019

People with higher multimorbidity scores have faster brain decline, greater suicide risk

Having arthritis, or diabetes, or heart disease can change a person's life, getting in the way of daily activities and requiring special diets and medicines.

20 Jun 2019

Study examines type of social interaction required for people to display physiological synchrony

A team of researchers led by a member of the Colorado School of Public Health faculty at the Anschutz Medical Campus examined what type of social interaction is required for people to display physiological synchrony--mutual changes in autonomic nervous system activity.

20 Jun 2019

Study: Arkansas Medicaid work requirements hit those already employed

The Medicaid work requirement plan devised by Arkansas and approved by the Trump administration backfired because it caused thousands of poor adults to lose coverage without any evidence the target population gained jobs, a new study finds.

19 Jun 2019

Deep sedation does not improve colonoscopy quality compared to moderate sedation

Colon cancer is the second leading cause of cancer death in the United States and colonoscopy is the most-used screening tool to detect it.

19 Jun 2019

Scientists pinpoint cause of fatal respiratory disorder that turns babies' lips and skin blue

Scientists used a gene editing method called CRISPR/Cas9 to generate mice that faithfully mimic a fatal respiratory disorder in newborn infants that turns their lips and skin blue. The new laboratory model allowed researchers to pinpoint the ailment's cause and develop a potential and desperately needed nanoparticle-based treatment.

19 Jun 2019

Three signs of real progress against sickle cell disease

A decade ago, the United Nations declared June 19 to be World Sickle Cell Awareness Day- and for good reason.

19 Jun 2019

Revolutionary cancer drugs that target any tumor to be fast-tracked into hospitals by NHS

Patients in England could be some of the first in the world to be treated with revolutionary cancer drugs that can target any type of tumor.

19 Jun 2019

Yale researchers offer insight into the hunger hormone

In a new study, Yale researchers offer insight into leptin, a hormone that plays a key role in appetite, overeating, and obesity. Their findings advance knowledge about leptin and weight gain, and also suggest a potential strategy for developing future weight-loss treatments, they said.

19 Jun 2019

Highlights and key takeaways from the 2019 Boston Bacterial Meeting (BBM)

Missed out on the 2019 Boston Bacterial Meeting (BBM)? Read our round-up of the key takeaways, areas of discussion, speakers and more.

19 Jun 2019

New chief medical officer appointed for Cancer Research UK’s Centre for Drug Development

Professor Peter Johnson will be the new chief medical officer for Cancer Research UK’s Centre for Drug Development, it was announced today (Tuesday).

19 Jun 2019

Healthy blood vessels could help stave off cognitive decline

High blood pressure may affect conditions such as Alzheimer’s disease by interfering with the brain’s waste management system, according to new research in rats published in JNeurosci. Maintaining blood vessel health could therefore help stave off cognitive decline.

From Society for Neuroscience 19 Jun 2019

Scientists develop universal FACS-based approach to heterogenous cell sorting, propelling organoid research

Researchers have developed three novel FACS protocols that can be used to isolate neural progenitors, astrocytes, and neurons from infected cerebral organoids.

19 Jun 2019

Medicine News and Research

Investigational drug for treatment of sickle cell disease shows early promise in clinical trials

Study reveals potential consequences of limiting ovarian cancer surgery to high-volume hospitals

Research findings lead to new clinical trial for people with myelofibrosis

New type of treatment for osteoarthritis shows promise for use in humans

Dangerous brain parasite invades host cell, maintains steady nutrient supply

Study: Melanin-concentrating hormone neurons in hypothalamus increase REM sleep

Researcher employs people who inject drugs to study factors influencing acquisition of HIV

Eyes hold clues to effective treatment of severe autism, study shows

People with higher multimorbidity scores have faster brain decline, greater suicide risk

Study examines type of social interaction required for people to display physiological synchrony

Study: Arkansas Medicaid work requirements hit those already employed

Deep sedation does not improve colonoscopy quality compared to moderate sedation

Scientists pinpoint cause of fatal respiratory disorder that turns babies' lips and skin blue

Three signs of real progress against sickle cell disease

Revolutionary cancer drugs that target any tumor to be fast-tracked into hospitals by NHS

Yale researchers offer insight into the hunger hormone

Highlights and key takeaways from the 2019 Boston Bacterial Meeting (BBM)

New chief medical officer appointed for Cancer Research UK’s Centre for Drug Development

Healthy blood vessels could help stave off cognitive decline

Scientists develop universal FACS-based approach to heterogenous cell sorting, propelling organoid research

Everything there is to know about biosimilars eBook

Managing vibration in IVF laboratories

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

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