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New type of vaccine holds promise for prevention of genital herpes

Scientists at Albert Einstein College of Medicine of Yeshiva University have designed a new type of vaccine that could be the first-ever for preventing genital herpes--one of the most common sexually transmitted diseases, affecting some 500 million people worldwide.

9 Mar 2015

Rare, aggressive subtype of pediatric acute lymphoblastic leukemia has surprisingly few mutations

The St. Jude Children's Research Hospital--Washington University Pediatric Cancer Genome Project reports that a highly aggressive form of leukemia in infants has surprisingly few mutations beyond the chromosomal rearrangement that affects the MLL gene. The findings suggest that targeting the alteration is likely the key to improved survival.

9 Mar 2015

Sunitinib holds promise for treatment of advanced differentiated thyroid cancer

In patients with advanced thyroid cancer, sunitinib, a drug approved for treatment of several other cancers, showed significant cancer-fighting activity t, a new phase 2 clinical trial has found. Results of the single-center study will be presented Sunday at the Endocrine Society's 97th annual meeting in San Diego.

9 Mar 2015

Genetically modified soybean oil has fewer negative metabolic consequences than regular soybean oil

A new soybean oil genetically modified to be healthier than conventional soybean oil causes obesity, pre-diabetes and fatty liver in a nearly identical manner to that of regular soybean oil when part of a typical American high-fat diet, an animal study shows.

6 Mar 2015

Better understanding of stomach's response to infection could lead to therapies against gastric damage

A better understanding of the stomach's immune response to Helicobater pylori (H. pylori) infection could lead to new therapies targeting damage in the stomach, report researchers in the March issue of Cellular and Molecular Gastroenterology and Hepatology, the basic science journal of the American Gastroenterological Association.

6 Mar 2015

Consuming popular dietary supplement ubiquinone unlikely to provide any benefit

The popular dietary supplement ubiquinone, also known as Coenzyme Q10, is widely believed to function as an antioxidant, protecting cells against damage from free radicals. But a new study by scientists at McGill University finds that ubiquinone is not a crucial antioxidant -- and that consuming it is unlikely to provide any benefit.

6 Mar 2015

Researchers present new findings about 'key players' involved in brain inflammation

Inflammatory processes occur in the brain in conjunction with stroke and neurological diseases such as Alzheimer's and Parkinson's disease. Researchers from Lund University and Karolinska Institutet in Sweden, in close cooperation with a group led by Professor José L. Venero at the University of Seville, have presented new findings about some of the 'key players' in inflammation.

6 Mar 2015

ULB researchers test therapeutic potential of cortical neurons developed in laboratory

Researchers at the ULB - IRIBHM and ULB Neuroscience Institute - have tested the therapeutic potential of cortical neurons generated at the laboratory, by transplantation in the brains of adult mice.

6 Mar 2015

GM soybean oil as unhealthy as regular soybean oil, but may not cause insulin resistance

Soybean oil accounts for more than 90 percent of all the seed oil production in the United States. Genetically modified (GM) soybean oil, made from seeds of GM soybean plants, was recently introduced into the food supply on the premise that it is healthier than conventional soybean oil.

6 Mar 2015

Preventing lung infections in childhood could help people with cystic fibrosis during adulthood

Preventing lung infections in childhood could stop later life-threatening infections for people with cystic fibrosis (CF), according to the latest research carried out at Aston University.

6 Mar 2015

CRISPR-Cas9 gene-editing technology targets every gene in the genome in animal cancer model

For the first time, CRISPR-Cas9 gene-editing technology has been employed in a whole organism model to systematically target every gene in the genome.

6 Mar 2015

Key 'energy producing' protein plays a critical role in a good immune system

A good immune system relies on a key 'energy producing' protein in immune cells to develop immunity to vaccines and disease, an international team of scientists has found.

6 Mar 2015

Non-viral gene therapy provides relief for diabetics with constant foot pain

Walking barefoot on sand "felt like walking on glass" for Keith Wenckowski, who has lived with type-one diabetes for more than two decades.

6 Mar 2015

RBFox2 protein plays critical role in heart failure

Researchers at the University of California, San Diego School of Medicine have identified a key piece in the complex molecular puzzle underlying heart failure - a serious and sometimes life-threatening disorder affecting more than 5 million Americans.

5 Mar 2015

LUNGevity applauds FDA's approval of Opdivo drug

LUNGevity Foundation, the nation's leading lung cancer nonprofit, applauds the Food and Drug Administration's approval of Bristol Myers Squibb's new immunotherapy drug Opdivo (nivolumab). Opdivo and other immunotherapy treatments add another critical new treatment option to fight lung cancer by harnessing the power of a patient's own immune system to fight cancerous cells.

5 Mar 2015

Leica Microsystems Launches FRAP Device for Widefield Microscopy

Leica Microsystems launches the Fluorescence Recovery After Photobleaching (FRAP) device for widefield microscopy, Leica WF FRAP. The device is made for the investigation of cellular dynamics and provides users the flexibility to define their bleaching area using masks of various sizes and shapes.

5 Mar 2015

Pediatric Cancer Genome Project identifies genetic basis of three pediatric melanoma subtypes

The St. Jude Children's Research Hospital—Washington University Pediatric Cancer Genome Project found that melanoma in some adolescent and adult patients involves many of the same genetic alterations and would likely respond to the same therapy.

5 Mar 2015

Northwestern scientists map brain circuit that processes temperature information

Innately, we pull our hand away when we touch a hot pan on the stove, but little is known about how our brain processes temperature information. Northwestern University scientists now have discovered how a fruit fly's brain represents temperature, mapping it neuron by neuron, which has implications for understanding the much more complex human brain and how it responds to sensory stimuli.

5 Mar 2015

New cell powerhouse sequencing technique may provide clearer picture of inherited disease risk

A new sequencing technique may provide a clearer picture of how genes in mitochondria, the "powerhouses" that turn sugar into energy in human cells, shape each person's inherited risk for diabetes, heart disease and cancer, according to a study conducted at the Icahn School of Medicine at Mount Sinai and published online this week in the journal Nucleic Acids Research.

5 Mar 2015

Study shows how mutations that cause Alzheimer's disease lead to neurodegeneration, dementia

A study from researchers at Massachusetts General Hospital and Brigham and Women's Hospital reveals for the first time exactly how mutations associated with the most common form of inherited Alzheimer's disease produce the disorder's devastating effects.

5 Mar 2015

B Cell News and Research

New type of vaccine holds promise for prevention of genital herpes

Rare, aggressive subtype of pediatric acute lymphoblastic leukemia has surprisingly few mutations

Sunitinib holds promise for treatment of advanced differentiated thyroid cancer

Genetically modified soybean oil has fewer negative metabolic consequences than regular soybean oil

Better understanding of stomach's response to infection could lead to therapies against gastric damage

Consuming popular dietary supplement ubiquinone unlikely to provide any benefit

Researchers present new findings about 'key players' involved in brain inflammation

ULB researchers test therapeutic potential of cortical neurons developed in laboratory

GM soybean oil as unhealthy as regular soybean oil, but may not cause insulin resistance

Preventing lung infections in childhood could help people with cystic fibrosis during adulthood

CRISPR-Cas9 gene-editing technology targets every gene in the genome in animal cancer model

Key 'energy producing' protein plays a critical role in a good immune system

Non-viral gene therapy provides relief for diabetics with constant foot pain

RBFox2 protein plays critical role in heart failure

LUNGevity applauds FDA's approval of Opdivo drug

Leica Microsystems Launches FRAP Device for Widefield Microscopy

Pediatric Cancer Genome Project identifies genetic basis of three pediatric melanoma subtypes

Northwestern scientists map brain circuit that processes temperature information

New cell powerhouse sequencing technique may provide clearer picture of inherited disease risk

Study shows how mutations that cause Alzheimer's disease lead to neurodegeneration, dementia

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