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KU researchers find potential therapeutic target for triple-negative breast cancer

A team at the University of Kansas School of Medicine has identified a potential target for treating breast cancer, including a particularly deadly form of the disease.

30 Oct 2014

Study reveals subtypes, potential diagnostic and treatment clues for papillary thyroid carcinomas

A comprehensive analysis of the genomes of nearly 500 papillary thyroid carcinomas (PTC) – the most common form of thyroid cancer – has provided new insights into the roles of frequently mutated cancer genes and other genomic alterations that drive disease development.

25 Oct 2014

Janssen announces submission of IMBRUVICA sNDA to FDA for WM treatment

Janssen Research & Development, LLC today announced the submission of a supplemental New Drug Application (sNDA) for IMBRUVICA (ibrutinib) to the U.S. Food and Drug Administration by its strategic partner Pharmacyclics, Inc.

20 Oct 2014

Testosterone therapy raises risk of prostate tumors in rats

A researcher who found that testosterone raised the risk of prostate tumors and exacerbated the effects of carcinogenic chemical exposure in rats is urging caution in prescribing testosterone therapy to men who have not been diagnosed with hypogonadism, according to a new study published in the Endocrine Society's journal Endocrinology.

7 Oct 2014

Scientists identify new biomarker for diagnosing cause of thyroid cancer

The expression of the protein CLIP2 provides information on whether a papillary thyroid carcinoma was induced by radiation or had a sporadic origin. With this discovery, scientists from the Helmholtz Zentrum München have identified a new biomarker for the diagnosis of the cancer cause.

7 Oct 2014

Abbvie announces multiple study results of veliparib investigational compound in NSCLC patients

AbbVie released interim results from an ongoing Phase 2 study of its investigational compound veliparib in combination with chemotherapy, which showed a 35 percent improvement (P-value=0.14) in progression-free survival (PFS) and a 30 percent improvement (P-value=0.21) in overall survival (OS) in patients with previously untreated metastatic or advanced non-small cell lung cancer (NSCLC).

30 Sep 2014

Dabrafenib shows significant anti-tumour activity in BRAF V600E mutant non-small cell lung cancer

The BRAF inhibitor dabrafenib has significant anti-tumour activity in patients with advanced BRAF V600E mutant non-small cell lung cancer whose disease has progressed after chemotherapy, according to phase II data presented at the ESMO 2014 Congress in Madrid, Spain.

29 Sep 2014

Oral afatinib significantly improves progression-free survival in patients with head and neck cancer

The tyrosine kinase inhibitor afatinib significantly improved progression-free survival compared to methotrexate in patients with recurrent or metastatic squamous cell carcinoma of the head and neck after failure of platinum-based chemotherapy, the results of a phase III trial show.

29 Sep 2014

Genetic mutation caused by ultraviolet light is likely driving force behind human skin cancers

A genetic mutation caused by ultraviolet light is likely the driving force behind millions of human skin cancers, according to researchers at the Stanford University School of Medicine.

8 Sep 2014

KIT spinoff amcure develops tumor therapeutic agents to reduce mortality rate

There is an urgent need for medical agents to treat metastatic tumors. In case of pancreatic cancer, one of the most aggressive types of cancer that is often detected late, 95% of the patients die within five years after the diagnosis.

30 Aug 2014

US lung cancer rates uncover trends related to cancer subtype, sex, race/ethnicity and age

A new analysis confirms that US lung cancer rates are declining overall, but it also uncovers previously unrecognized trends related to cancer subtype, sex, race/ethnicity, and age.

11 Aug 2014

Research points to new direction for potential therapies to treat mucoepidermoid carcinoma

Research conducted at the Florida campus of The Scripps Research Institute has discovered links between a set of genes known to promote tumor growth and mucoepidermoid carcinoma, an oral cancer that affects the salivary glands. The discovery could help physicians develop new treatments that target the cancer's underlying genetic causes.

29 Jul 2014

Montefiore-Einstein investigators to present new findings from eight abstracts at IFHNOS 2014

Clinicians and researchers from Montefiore Medical Center and the Albert Einstein College of Medicine of Yeshiva University will present new findings from eight abstracts at the International Federation of Head and Neck Oncologic Societies World Congress being held July 26 - July 30 in New York.

26 Jul 2014

CFDA approves CASI's ENMD-2076 Phase II trial in triple-negative breast cancer patients

CASI Pharmaceuticals, Inc., a clinical-stage pharmaceutical company developing therapeutics for the treatment of cancer and other diseases, announced today that China's Food and Drug Administration has approved the Company's application to conduct a Phase II clinical trial in triple-negative breast cancer (TNBC) patients in China for its proprietary drug candidate, ENMD-2076.

21 Jul 2014

Metvix PDT now available at Odette Cancer Centre as additional treatment option for NMSC patients

The Odette Cancer Centre at Sunnybrook Health Sciences Centre in conjunction with Galderma Canada are pleased to announce that Metvix PDT (Photodynamic Therapy), is now available at the Odette Cancer Centre in Toronto as an additional treatment option for patients with NMSC (non-melanoma skin cancer).

15 Jul 2014

Research demonstrates new computer software to help diagnose cancer cells

In pathology, cells and cell nuclei are usually examined using a microscope for bio-marker expressions in tumours. This analysis is used to weigh up the treatment options for patients who have cancer, for example.

15 Jul 2014

Researchers develop new software to identify severity of cancer

Together with the company Tissuegnostics, the pathologist Lukas Kenner and his colleagues have developed a software that is able to identify cancer cells in tissue sections and demonstrate the presence of specific biomarkers on cells. The overall information provides a precise picture of the disease and leads to the most suitable treatment.

15 Jul 2014

CASI's ENMD-2076 gets FDA Orphan Drug designation for HCC treatment

CASI Pharmaceuticals, Inc., a clinical-stage pharmaceutical company developing therapeutics for the treatment of cancer and other diseases, announced today that its orally-active, Aurora A/angiogenic kinase inhibitor, ENMD-2076, has received Orphan Drug designation from the U.S. Food and Drug Administration for the treatment of hepatocellular carcinoma (HCC).

7 Jul 2014

Loss of p62 protein in cells and tissue surrounding a tumor can influence tumor growth

A team of scientists from Sanford Burnham Medical Research Institute has found that the loss of a protein called p62 in the cells and tissue surrounding a tumor can enhance the growth and progression of tumors.

4 Jul 2014

Exposure to ultraviolet radiation lamps used for indoor tanning increases risk of developing BCC

Dartmouth researchers have found that early exposure to the ultraviolet radiation lamps used for indoor tanning is related to an increased risk of developing basal cell carcinomas (BCC) at a young age.

23 Jun 2014

Carcinomas News and Research

KU researchers find potential therapeutic target for triple-negative breast cancer

Study reveals subtypes, potential diagnostic and treatment clues for papillary thyroid carcinomas

Janssen announces submission of IMBRUVICA sNDA to FDA for WM treatment

Testosterone therapy raises risk of prostate tumors in rats

Scientists identify new biomarker for diagnosing cause of thyroid cancer

Abbvie announces multiple study results of veliparib investigational compound in NSCLC patients

Dabrafenib shows significant anti-tumour activity in BRAF V600E mutant non-small cell lung cancer

Oral afatinib significantly improves progression-free survival in patients with head and neck cancer

Genetic mutation caused by ultraviolet light is likely driving force behind human skin cancers

KIT spinoff amcure develops tumor therapeutic agents to reduce mortality rate

US lung cancer rates uncover trends related to cancer subtype, sex, race/ethnicity and age

Research points to new direction for potential therapies to treat mucoepidermoid carcinoma

Montefiore-Einstein investigators to present new findings from eight abstracts at IFHNOS 2014

CFDA approves CASI's ENMD-2076 Phase II trial in triple-negative breast cancer patients

Metvix PDT now available at Odette Cancer Centre as additional treatment option for NMSC patients

Research demonstrates new computer software to help diagnose cancer cells

Researchers develop new software to identify severity of cancer

CASI's ENMD-2076 gets FDA Orphan Drug designation for HCC treatment

Loss of p62 protein in cells and tissue surrounding a tumor can influence tumor growth

Exposure to ultraviolet radiation lamps used for indoor tanning increases risk of developing BCC

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