Clostridium News and Research

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UTHealth scientist receives $1.9 million from NIH to develop non-antibiotic treatment for C. diff infections

Charles Darkoh, Ph.D., a researcher at The University of Texas Health Science Center at Houston School of Public Health, was recently awarded a five-year, $1.9 million R01 grant by the National Institutes of Health to develop a non-antibiotic treatment for Clostridium difficile (C. diff) infections.

10 Jul 2015

MU scientists develop RNAMiner tool to make genetic science easier

Technology rapidly is advancing the study of genetics and the search for causes of major diseases. Analysis of genomic sequences that once took days or months now can be performed in a matter of hours. Yet, for most genetic scientists, the lack of access to computer servers and programs capable of quickly handling vast amounts of data can hinder genetic advancements.

8 Jul 2015

New collection of papers adds to mounting evidence of gut microbiome’s influential role in health

A newly released collection of papers, the result of the Gut in Focus Symposium Nobel Forum held earlier this year, is adding to the mounting evidence of the influential role the gut microbiome plays in health.

1 Jul 2015

IPs spend more time in collecting and reporting hospital infection data than protecting patients

Collecting and reporting hospital infection data to federal health agencies takes more than 5 hours each day, at the expense of time needed to ensure that frontline healthcare personnel are adhering to basic infection prevention practices such as hand hygiene, according to a recent case study, to be presented on Saturday, June 27 at the 42nd Annual Conference of the Association for Professionals in Infection Control and Epidemiology.

26 Jun 2015

NHS Scotland's Golden Jubilee National Hospital deploys MicroStrategy platforms to improve patient care, enhance operations

MicroStrategy® Incorporated, a leading worldwide provider of enterprise software platforms, today announced that NHS Scotland's Golden Jubilee National Hospital has deployed the MicroStrategy Analytics Platform™ and MicroStrategy Mobile™ to monitor, report, and analyze over 200 quality indicators consisting of patient care, staffing, and performance metrics.

24 Jun 2015

Stable IV formulation to treat systemic susceptible and resistant Gram-positive hospital-acquired infections

MGB Biopharma, a biopharmaceutical company developing a truly novel class of anti-infectives, to address the major global problem of antibiotic resistance - announces that it has developed a stable intravenous (IV) formulation of MGB-BP-3, designed for the treatment of systemic susceptible and resistant Gram-positive hospital-acquired infections.

2 Jun 2015

Roche announces FDA clearance for cobas Cdiff Test to detect C. difficile in stool specimens

Roche announced today that the US Food and Drug Administration has provided 510(k) clearance for the cobas Cdiff Test to detect Clostridium difficile (C. difficile) in stool specimens.

26 May 2015

CSGI joins with two California hospitals to eradicate deadly Clostridium difficile infections

Clean Sweep Group Inc., a Beverly Hills, CA, based microbial disinfection service company, joins with two California hospitals to significantly reduce deadly Clostridium difficile infections caught in their hospitals using ultraviolet (UV-C) germ-killing advanced disinfection devices.

21 May 2015

Endo Pharmaceuticals supports efforts to bring first ever treatment guidelines for Peyronie's Disease

Endo Pharmaceuticals Inc., a subsidiary of Endo International plc, supports efforts to bring the medical community the first ever treatment guidelines for Peyronie's Disease (PD), a condition in which collagen plaque, or scar tissue, develops on the shaft of the penis, and may harden and reduce flexibility.

19 May 2015

Endo Announces Updated XIAFLEX® Label in Patients with Dupuytren’s Contracture

DC is a chronic condition affecting the hand in which abnormal buildup of collagen can cause the fingers to bend and be drawn in toward the palm...

18 May 2015

Treatment significantly reduces risk of CDI recurrence

Among patients with Clostridium difficile infection (CDI) who recovered following standard treatment with the antibiotics metronidazole or vancomycin, oral administration of spores of a strain of C difficile that does not produce toxins colonized the gastrointestinal tract and significantly reduced CDI recurrence, according to a study in the May 5 issue of JAMA.

7 May 2015

Fecal transplantation cures C. diff infection, eliminates multi-drug resistant pathogens

A fecal microbiota transplant (FMT) not only cured a case of Clostridium difficile (C. diff) infection in a 66 year old man; it eliminated populations of multi-drug resistant organisms both in the patient's gastrointestinal tract, and several other body sites.

7 May 2015

Luminex provides clinical trial update on ARIES HSV 1&2 Assay

Luminex Corporation today announced that testing at the clinical trial sites for the ARIES HSV 1&2 Assay is now complete. The next steps, including site to site reproducibility testing, followed by data analysis and assembly of the data package for submission to the FDA, are now underway.

From Luminex 28 Apr 2015

U-M study: Nearly half of American hospitals not taking key steps to prevent C. diff infections

Nearly half of American hospitals aren't taking key steps to prevent a kind of gut infection that kills nearly 30,000 people annually and sickens hundreds of thousands more - despite strong evidence that such steps work, according to a new study.

25 Apr 2015

Infectious diseases experts release new guidance to avoid infections during hospital visits

Leading infectious diseases experts have released new guidance for healthcare facilities looking to establish precautions for visitors of patients with infectious diseases. The guidance looks to reduce the potential for healthcare visitors in spreading dangerous bacteria within the healthcare facility and community.

13 Apr 2015

Fecal microbiota transplantation more successful for treating Clostridium difficile infections

Distasteful though it sounds, the transplantation of fecal matter is more successful for treating Clostridium difficile infections than previously thought.

30 Mar 2015

Study finds C. difficile infection increases hospital readmission rates

Patients with Clostridium difficile infection (CDI) are twice as likely to be readmitted to the hospital as patients without the deadly diarrheal infection, according to a study published in the April issue of the American Journal of Infection Control, the official publication of the Association for Professionals in Infection Control and Epidemiology.

30 Mar 2015

BioSpecifics Technologies provides corporate update, reports Q4 and FY 2014 financial results

BioSpecifics Technologies Corp., a biopharmaceutical company developing first in class collagenase-based products marketed as XIAFLEX (collagenase clostridium histolyticum or CCH) in the U.S. and XIAPEX® in the EU, today announced its financial results for the fourth quarter and full year ended December 31, 2014 and provided a corporate update.

13 Mar 2015

Aggressive campaign to cut unnecessary use of antibiotics helps reduce drug-resistant bacteria

An aggressive campaign to reduce the unnecessary use of antibiotics has helped cut the rate of infection with a dangerous drug-resistant bacteria at The Valley Hospital by nearly 40 percent.

28 Feb 2015

Deadly C. difficile affected almost half a million in the U.S over one year

The deadly bug Clostridium difficile (C. diff) infected more than 450,000 people in the U.S in a single year, according to new research funded by the Centers for Disease Control and Prevention (CDC).

26 Feb 2015