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$VT3989 shows promising antitumor activity in refractory mesothelioma patients$

VT3989 shows promising antitumor activity in refractory mesothelioma patients

The first-in-class YAP-TEAD inhibitor VT3989 continued to be well tolerated and demonstrated notable initial antitumor activity, particularly in patients with refractory mesothelioma, according to results from a trial led by researchers from The University of Texas MD Anderson Cancer Center.

22 Oct 2025

New AI-driven approach identifies treatments to reprogram and destroy cancer stem cells

Scientists at University of California San Diego have developed a new approach to destroying cancer stem cells – hard-to-find cells that help cancers spread, come back after treatment and resist therapy.

21 Oct 2025

Can fitness apps and wearables make children healthier? This study says yes - partly

Digital health tools such as apps, wearables, and web platforms can modestly improve children’s physical activity, diet, and weight outcomes. Shorter programs boost activity, while longer ones better support weight management, though effects on sleep and sedentary time remain unclear.

20 Oct 2025

Pin1 inhibitors could reduce or stop outbreaks of herpes simplex virus 1

A class of antivirals called Pin1 inhibitors could reduce or stop outbreaks of herpes simplex virus 1 (HSV-1), the common infection behind oral herpes, according to new research published in Antiviral Research on July 25.

17 Oct 2025

An age-old fear grows more common: ‘I’m going to die alone’

This summer, at dinner with her best friend, Jacki Barden raised an uncomfortable topic: the possibility that she might die alone.

16 Oct 2025

Caraway seeds inspire new seizure-fighting medicines

A UNLV-led team of researchers has co-opted a common kitchen spice to create a new class of cannabidiol (CBD)-like medicines that show powerful seizure-reducing effects - offering a safer, more affordable, and more effective treatment for childhood seizure disorders than existing frontline therapies.

15 Oct 2025

Astrocytes revealed as key players in stabilizing long-term emotional memories

Why are we able to recall only some of our past experiences? A new study led by Jun Nagai at the RIKEN Center for Brain Science in Japan has an answer.

15 Oct 2025

Psychedelics could alter treatment paradigms for stress-related mental health conditions

A peer-reviewed viewpoint article published today in Psychedelics by Prof. Xiaohui Wang and colleagues examines the therapeutic potential of psychedelic substances for treating stress-related psychiatric disorders through novel neurobiological mechanisms.

14 Oct 2025

Wiley announces support for Nanalysis NMR instruments in KnowItAll 2026

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From John Wiley and Sons - Scientific Publishers 14 Oct 2025

Targeting SIRT7 offers new strategy against liver fibrosis

Liver fibrosis, a progressive scarring of the liver tissue, represents a major global health burden with limited treatment options.

10 Oct 2025

Natural nasal microbes offer broad-spectrum antiviral protection

Respiratory viral diseases pose severe threats to animal health and global food security, especially in intensive pig farming systems.

10 Oct 2025

Chlorinated compounds from slime mold show strong antibacterial activity

The cellular slime mold Dictyostelium discoideum is a soil microbe that produces diverse natural products with potential antibiotic activity.

9 Oct 2025

Researchers discover how plants produce cancer-fighting mitraphylline

Researchers at UBC Okanagan have uncovered how plants produce mitraphylline, a rare natural compound that may help fight cancer.

8 Oct 2025

New drug candidates show promise for restoring myelin in MS

Multiple sclerosis, or MS, is a chronic autoimmune disease affecting more than 2.9 million people worldwide.

8 Oct 2025

Breakthrough in RNA-targeted drug discovery offers hope against viral diseases

In a quest to develop new antiviral drugs for COVID-19 and other diseases, a collaboration led by scientists at The Wertheim UF Scripps Institute has identified a potential new drug against the virus that causes COVID-19.

6 Oct 2025

Penn Medicine study maps brain circuits impacted by psilocybin

Researchers at Penn Medicine have identified specific brain circuits that are impacted by psilocybin-the active compound found in some psychedelic mushrooms-which could lead to new paths forward for pain and mental health management options.

2 Oct 2025

New study reveals molecular basis of Long COVID brain fog

Even though many years have passed since the start of the COVID-19 pandemic, the effects of infection with SARS-CoV-2 are not completely understood.

30 Sep 2025

Targeting the cerebellum to ease alcohol withdrawal symptoms

By targeting a specific area of the brain, researchers at Washington State University may now hold the key to curbing the debilitating symptoms of alcohol withdrawal that push many people back to drinking.

30 Sep 2025

Undiagnosed G6PD deficiency can lead to delayed diabetes diagnosis for Black and Asian men

A common but often undiagnosed genetic condition may be causing delays in type 2 diabetes diagnoses and increasing the risk of serious complications for thousands of Black and South Asian men in the UK - and potentially millions worldwide.

30 Sep 2025

Small molecule AVJ16 shows promise in targeting lung cancer growth

Researchers have discovered a promising new approach to lung cancer treatment. A small molecule called AVJ16 selectively blocks the cancer-driving protein IGF2BP1, halting tumor growth in preclinical studies and killing cancer cells in patient-derived models—while leaving healthy cells unharmed.

29 Sep 2025