Free Radicals News and Research

RSS

Age may play major role in cell's ability to respond to physical exercise

If you're an older adult, a 30-minute workout may not be as effective, even at the cellular level, as it was when you were younger.

9 Jun 2016

CSU researchers develop colorful potatoes that are high in antioxidants, rich in nutrients

Purple potatoes might not be the first thing that comes to mind when trying to increase vitamin, mineral and antioxidant intake. However, a group of researchers from Colorado State University have recently developed potato varieties that satisfy these nutritional needs and could act as a preventive measure to several diseases.

23 May 2016

High-level quantum chemical computations help unravel underlying mechanism of hepatocellular toxicity

Balasubramanian and Basak have recently reported quantum chemical computations that enhance our understanding of mechanisms for the causes of liver toxicity. Hepatocellular carcinoma is one of the most common forms of cancer, and the primary cause has been attributed to liver fibrosis by chemical toxins, which is followed by liver cirrhosis.

9 May 2016

Scientists identify critical biological factor for transforming adult somatic cells into stem cells

In a new Cell Reports paper, a team led by John P. Cooke, M.D., Ph.D., of the Houston Methodist Research Institute, has identified and characterized a biological factor critical to the transformation of adult somatic cells (cells that are not sperm or egg cells) into stem cells.

22 Apr 2016

Six newly identified proteins may help potentially unlock new insights into aging-related diseases

A group of six newly discovered proteins may help to divulge secrets of how we age, potentially unlocking new insights into diabetes, Alzheimer's, cancer, and other aging-related diseases.

12 Apr 2016

Maternal obesity, poor nutrition during pregnancy affect egg reserves of female child

New research involving mice, published in the April 2016 issue of The FASEB Journal, suggests that maternal obesity and poor nutrition during pregnancy affects the egg reserves of female offspring. This discovery improves scientific understanding of the long-term, generational, effects of obesity and poor nutrition. This understanding is the first step toward devising interventions to protect the fertility of females who experienced very difficult womb environments.

11 Apr 2016

Commonly used fungicides could cause gene expression changes in brain cells

Scientists at the UNC School of Medicine have found a class of commonly used fungicides that produce gene expression changes similar to those in people with autism and neurodegenerative conditions, including Alzheimer's disease and Huntington's disease.

31 Mar 2016

New Rutgers study links protein that helps fight infection to heart and liver disease

A protein that should help fight infection and keep us healthy may be targeted for treating devastating illnesses like heart and liver disease, according to a new Rutgers study.

31 Mar 2016

Protease inhibitors may prevent cardiovascular disease risk caused by HIV medications

According to the World Health Organization, approximately 37 million people are living with HIV. Antiviral medications are used to control the disease and prevent its progression to AIDS.

29 Mar 2016

SLU scientist describes several tactics that can help cells overcome lesions

In a recent review paper published in Nature Structural & Molecular Biology, SLU scientist Alessandro Vindigni, Ph.D., describes the strategies cells use when their DNA faces replication stress, challenges that may derail a cell's ability to reproduce.

29 Mar 2016

Neuroscientists decipher new pathway in stem cell differentiation

How do neurons become neurons? They all begin as stem cells, undifferentiated and with the potential to become any cell in the body.Until now, however, exactly how that happens has been somewhat of a scientific mystery. New research conducted by UC Santa Barbara neuroscientists has deciphered some of the earliest changes that occur before stems cells transform into neurons and other cell types.

25 Mar 2016

High-intensity workout could do more harm than good

High-intensity 'sprint training' may be gaining popularity at gyms, but if you're new to this form of exercise, the workout could do more harm than good.

24 Mar 2016

Global improvement in antioxidant capacity may delay ageing

The gradual accumulation of cell damage plays a very important role in the origin of ageing. There are many sources of cellular damage, however, which ones are really responsible for ageing and which ones are inconsequential for ageing is a question that still lacks an answer

17 Mar 2016

Cell-based tests reveal no activity in cells exposed to vapour from Vype ePen

A series of cell-based tests developed to compare the biological impact of cigarette smoke with e-cigarette vapour revealed no activity in cells exposed to vapour from Vype ePen, a commercially available e-cigarette.

16 Mar 2016

Researchers reveal link between mitochondrial dysfunction and Fuchs' Endothelial Corneal Dystrophy

Researchers at Schepens Eye Research Institute of Massachusetts Eye and Ear have shown a link between mitochondrial dysfunction in corneal endothelial cells and the development of Fuchs' Endothelial Corneal Dystrophy.

4 Mar 2016

Research shows how developing neurons use copper for their various needs

Researchers at Johns Hopkins have used a precision sensor in a chicken embryo to find dramatic differences in the use of copper between developing and fully mature neurons.

17 Feb 2016

Mitochondria essential for cellular ageing

An international team of scientists has for the first time shown that mitochondria, the batteries of the cells, are essential for ageing.

5 Feb 2016

Duke researchers identify promising target for renal cell carcinomas

All cells need nutrients, but cancer cells are notoriously power hungry. As a result, cancer cells must alter their metabolism to provide the additional fuel needed for them to survive, grow and spread.

4 Feb 2016

New discovery may help researchers tackle mitochondrial diseases and age-related diseases

Buck Institute faculty Judith Campisi, PhD, says age researchers need to stop thinking of cellular senescence, now accepted as an important driver of aging, as a single phenotype that stems from genotoxic stress. Research from her lab reveals that cellular senescence, a process whereby cells permanently lose the ability to divide, is also induced by signaling from dysfunctional mitochondria - and that the arrested cells secrete a distinctly different "stew" of biologically active factors in a process unrelated to the damaging free radicals that are created in mitochondria as part of oxygen metabolism.

13 Jan 2016

Cancer drug may protect kidneys from damage caused by chemotherapy agent cisplatin

A class of drugs used increasingly to help fight cancer may have the additional benefit of protecting the kidneys when packaged with the powerful chemotherapy agent cisplatin.

16 Dec 2015