Liquid Chromatography News and Research

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Dual therapeutic potential of zapnometinib against COVID-19

Researchers assessed the impact of the drug zapnometinib on human immune response against coronavirus disease 2019.

2 Mar 2022

Study finds Omicron sublineage BA.2 is less pathogenic in rodent models than prior SARS-CoV-2 variants

Researchers evaluated the pathogenicity and replication potential of SARS-CoV-2 VOC Omicron lineage, BA.2 in immunocompetent mice and hamsters.

28 Feb 2022

Surfactant-containing oral mouthwashes target the lipid envelope of SARS-CoV-2

Researchers demonstrated the composition and importance of SARS-CoV-2 lipid envelope and assessed the antiviral potential of oral mouthwashes targeting these lipid envelopes.

21 Feb 2022

The impact of SARS-CoV-2 on lipids

SARS-CoV-2 appears to alter host lipid biosynthesis by relying on certain human metabolic pathways to survive and multiply effectively.

20 Feb 2022

Researchers use an integrated approach to reveal constituents in a multi-herb Chinese medicine

Rooted in ancient knowledge and principles, traditional Chinese medicine (TCM) has been used to treat many diseases, sparking the interest of pharmaceutical researchers. TCM formulas are quite complex, requiring multiple herbs for their formulation.

18 Feb 2022

Role of quantitative, multiplexed, targeted proteomics in determining variant-specific SARS-CoV-2 antibody response

Researchers developed a ‘bait and capture’ system which was further followed by a multiplexed and targeted proteomic liquid chromatography-tandem mass spectrometry analyses for the comparison of immune correlates in response to vaccination, natural infection, as well as protection against SARS-CoV-2 variants.

18 Feb 2022

Properties and pharmacokinetics an oral drug candidate for COVID-19 treatment

Researchers studied the preclinical PK) and in vitro ADME properties of GS-441524, a potential oral drug for COVID-19 treatment.

10 Feb 2022

Impact of DNA clearance on mortality in patients with severe COVID-19 infections

In a new study, researchers conducted activity-based proteomic profiling of patients who had severe SARS-CoV-2 infections to understand the impact of DNA clearance on mortality.

28 Jan 2022

Alterations of sphingolipids and their metabolizing enzymes in hospitalized or convalescent COVID-19 patients

An interdisciplinary team of researchers from Europe analyzed the alterations of sphingolipids and their metabolizing enzymes in hospitalized or convalescent COVID-19 patients.

26 Jan 2022

Paxlovid provides a glimpse into the future against SARS-CoV-2

A recent study reveals that nirmatrelvir is potent and effective against the SARS-CoV-2 Omicron variant.

23 Jan 2022

Echinacea as a potential force against coronavirus infections

A new review identified clinical studies evaluating coronavirus infections in the context of Echinacea administration and assessed preventive and therapy advantages against COVID-19.

21 Jan 2022

Mapping peripheral blood glycoprotein profiles of COVID-19 patients

A team of researchers recently analyzed differential protein glyco-isoform distributions of symptomatic and asymptomatic coronavirus disease 2019 patients.

11 Jan 2022

Collaborative approaches to honey adulteration detection

In this interview, we spoke to Marisa Amadei and Professor Norberto Luis Garcia to explore the impact of honey fraud on global food supply chains.

From Bruker BioSpin Division 10 Jan 2022

Study provides deeper insights into familial Alzheimer's disease pathogenesis

Alzheimer's disease (AD) is a progressive neurological disease that causes impairments in memory and cognition. AD is believed to result from the deposition of protein "plaques" consisting of amyloid beta (Aβ) proteins sequentially generated via the enzyme γ-secretase.

7 Jan 2022

Liquid Chromatography News and Research

Dual therapeutic potential of zapnometinib against COVID-19

Study finds Omicron sublineage BA.2 is less pathogenic in rodent models than prior SARS-CoV-2 variants

Surfactant-containing oral mouthwashes target the lipid envelope of SARS-CoV-2

The impact of SARS-CoV-2 on lipids

Researchers use an integrated approach to reveal constituents in a multi-herb Chinese medicine

Role of quantitative, multiplexed, targeted proteomics in determining variant-specific SARS-CoV-2 antibody response

Properties and pharmacokinetics an oral drug candidate for COVID-19 treatment

Impact of DNA clearance on mortality in patients with severe COVID-19 infections

Alterations of sphingolipids and their metabolizing enzymes in hospitalized or convalescent COVID-19 patients

Paxlovid provides a glimpse into the future against SARS-CoV-2

Echinacea as a potential force against coronavirus infections

Mapping peripheral blood glycoprotein profiles of COVID-19 patients

Collaborative approaches to honey adulteration detection

Study provides deeper insights into familial Alzheimer's disease pathogenesis

Exploring the impact of DNA nanoswitches in RNA purification

SARS-CoV-2 patients exhibit high specialized pro-resolving molecule serum levels

Multiplex proteomic panel assay for assessment of disease severity and outcome prediction in COVID-19

Virginia Tech researchers discover potential target for diagnosing and treating Lyme disease

From tiny particles to big success: Knauer awarded the innovation prize for Berlin Brandenburg

Oral Hsp90 inhibitor SNX-5422 interferes with replication machinery of SARS-CoV-2

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

Latest eBooks

A practical guide to lipid nanoparticle formulation and resizing

Editorial Focus eBook - Spatial and single-cell omics (1st edition)

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Single-cell proteomics: Revealing proteome diversity from cellular heterogeneity to non-canonical biology

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories