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Researchers demonstrate simple approach to prove how classes of new drugs work

A collaborative effort by cancer researchers at Cold Spring Harbor Laboratory and chemists at Boehringer Ingelheim, a pharmaceutical firm, has resulted in the identification of a new drug target in leukemia and creation of a candidate drug that hits the target.

6 Jul 2016

Article reviews impact of adding pyridine based antitumor compounds at colchicine site

Tubulin inhibitors are amongst the most successful anti-cancer, anti-parasitic and herbicidal agents. Their vascular disrupting activity has recently attracted research focus as it elicits anti-cancer effects at doses well below that of other toxic agents.

4 Jul 2016

Chemoradiotherapy and post-operative chemotherapy provide similar outcomes in gastric cancer patients

Post-operative treatment intensification with chemoradiotherapy does not achieve better outcomes when compared to post-operative chemotherapy in patients with gastric cancer who have already undergone pre-operative chemotherapy, according to phase III data presented at the ESMO 18th World Congress of Gastrointestinal Cancer in Barcelona, Spain.

4 Jul 2016

New supplement could help reduce urge to consume high-calorie foods

Eating a type of powdered food supplement, based on a molecule produced by bacteria in the gut, reduces cravings for high-calorie foods such as chocolate, cake and pizza, a new study suggests.

1 Jul 2016

Researchers find main cause of necrotizing enterocolitis-related lung damage in preemies

Johns Hopkins researchers report they have figured out a root cause of the lung damage that occurs in up to 10 percent of premature infants who develop necrotizing enterocolitis, a disorder that damages and kills the lining of the intestine.

29 Jun 2016

Compounds extracted from parsley and dill seeds may help fight cancer

A team of Russian scientists from Moscow Institute of Physics and Technology, the N. D. Zelinsky Institute of Organic Chemistry, the Institute of Developmental Biology, and the Institute of Cell Biophysics proposed an efficient approach to a novel agents with anticancer activity.

29 Jun 2016

Jefferson researchers discover alternate pathway that helps heart keep pumping

About 5.7 million Americans have heart failure, half of whom will die from the disease within 5 years, according to the Centers for Disease Control and Prevention.

28 Jun 2016

New non-invasive method may help treat people with inoperable or hard-to-reach tumors

Matthew Gdovin, an associate professor in the UTSA Department of Biology, has developed a newly patented method to kill cancer cells.

28 Jun 2016

Researchers receive grant to improve quality of donor limb, tissue for transplant

A Case Western Reserve University School of Medicine faculty member has received $998,500 from the U.S. Department of Defense to develop a new approach to improve the quality and quantity of limbs and tissues obtained from brain dead organ donors.

27 Jun 2016

Researchers identify new potential target for pancreatic cancer treatment

Using an innovative approach to identify a cancer's genetic vulnerabilities by more swiftly analyzing human tumors transplanted into mice, researchers have identified a new potential target for pancreatic cancer treatment, published online in Cell Reports.

24 Jun 2016

Broccoli sprout extract may help prevent cancer recurrence in head and neck cancer survivors

Potent doses of broccoli sprout extract activate a "detoxification" gene and may help prevent cancer recurrence in survivors of head and neck cancer, according to a trial by the University of Pittsburgh Cancer Institute, partner with UPMC CancerCenter, confirming preliminary results presented last year at the American Association for Cancer Research Annual Meeting.

24 Jun 2016

Researchers develop new formulations for topical treatments of oral mucosal conditions

On June 24, 2016, at the 94th General Session & Exhibition of the International Association for Dental Research, researcher W. Peter Holbrook, University of Iceland, will present a study titled "Development of Drugs for Local Treatment of Oral Conditions." The IADR General Session is being held in conjunction with the 3rd Meeting of the IADR Asia Pacific Region and the 35th Annual Meeting of the IADR Korean Division.

24 Jun 2016

Neurotherapeutic video game may help improve cognitive abilities in children with genetic disorders

A UC Davis researcher has created a video game for children who experience cognitive impairments from genetic disorders with the hope that that it will improve their ability to mentally process information about space and time.

23 Jun 2016

Researchers identify candidate genes controlling phenolic compound accumulation in broccoli

Love it or hate it, broccoli is touted as a superfood, offering an array of health benefits. And it's about to get even more super.

23 Jun 2016

Hops show promise in reducing breast cancer risk

Hops, the flower cones used in beer-making, are also found in dietary supplements designed to help treat post-menopausal symptoms and other conditions. Scientists are now investigating whether an extract from the plant could also help fend off breast cancer.

22 Jun 2016

Study links brain chemistry and fluid intelligence in living humans

A new study begins to clarify how brain structure and chemistry give rise to specific aspects of "fluid intelligence," the ability to adapt to new situations and solve problems one has never encountered before.

21 Jun 2016

Fetal BPA exposure leads to harmful change in adult uterine response to estrogens

Low levels of BPA exposure may be considered safe, but new research published online in The FASEB Journal, suggests otherwise. In the report, researchers from Yale show that the genome is permanently altered in the uterus of mice that had been exposed to BPA during their fetal development.

17 Jun 2016

Researchers seek to develop inexpensive electronic nose for breath analysis

Researchers at the Texas Analog Center of Excellence (TxACE) at UT Dallas are working to develop an affordable electronic nose that can be used in breath analysis for a wide range of health diagnosis.

17 Jun 2016

Investigators find ways to improve patient-practitioner communication in fertility clinics

One in every eight couples struggles to conceive or maintain a pregnancy. In Charlotte, at least 4,000 people seek infertility treatment every year. As such, the city has become a hub of knowledge and resources for patients diagnosed with infertility.

17 Jun 2016

New molecular breast imaging gives better image quality with reduced radiation dose

Preliminary tests have demonstrated that a new device may enable existing breast cancer imagers to provide up to six times better contrast of tumors in the breast, while maintaining the same or better image quality and halving the radiation dose to patients.

17 Jun 2016

Compound News and Research

Researchers demonstrate simple approach to prove how classes of new drugs work

Article reviews impact of adding pyridine based antitumor compounds at colchicine site

Chemoradiotherapy and post-operative chemotherapy provide similar outcomes in gastric cancer patients

New supplement could help reduce urge to consume high-calorie foods

Researchers find main cause of necrotizing enterocolitis-related lung damage in preemies

Compounds extracted from parsley and dill seeds may help fight cancer

Jefferson researchers discover alternate pathway that helps heart keep pumping

New non-invasive method may help treat people with inoperable or hard-to-reach tumors

Researchers receive grant to improve quality of donor limb, tissue for transplant

Researchers identify new potential target for pancreatic cancer treatment

Broccoli sprout extract may help prevent cancer recurrence in head and neck cancer survivors

Researchers develop new formulations for topical treatments of oral mucosal conditions

Neurotherapeutic video game may help improve cognitive abilities in children with genetic disorders

Researchers identify candidate genes controlling phenolic compound accumulation in broccoli

Hops show promise in reducing breast cancer risk

Study links brain chemistry and fluid intelligence in living humans

Fetal BPA exposure leads to harmful change in adult uterine response to estrogens

Researchers seek to develop inexpensive electronic nose for breath analysis

Investigators find ways to improve patient-practitioner communication in fertility clinics

New molecular breast imaging gives better image quality with reduced radiation dose

Enhancing confidence in chemical ionization spectrometry data eBook

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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