Metastasis News and Research

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Metastasis is the spread of cancer from one part of the body to another. A tumor formed by cells that have spread is called a “metastatic tumor” or a “metastasis.” The metastatic tumor contains cells that are like those in the original (primary) tumor. The plural form of metastasis is metastases

Gene expression and lung cancer prognosis

While there have been significant advances in the use of gene expression profiling to assess a cancer prognosis, a Mayo Clinic review and analysis of existing lung cancer studies shows that this technology has not yet surpassed the accuracy of conventional methods used to assess survival in lung cancer patients.

19 Nov 2006

Lab-on-a-chip nanoscale array monitors cellular processes

Researchers at Tel-Aviv University in Israel have developed a lab-on-a-chip device that can incorporate enzymes and even living cells in a nanoscale array capable of monitoring electrochemical reactions.

30 Oct 2006

New technique detects signature of metastasizing melanoma with as few as 10 cancer cells present in blood sample

Researchers at the University of Missouri-Columbia can now detect the spread of skin cancer cells through the blood by literally listening to their sound.

16 Oct 2006

p120 catenin protein can stop metastasis or promote it

A protein known to be a key component of the glue that holds cells together also is involved in breaking them apart and promoting their movement when tumors begin to spread to other parts of the body, researchers at Mayo Clinic have found.

20 Sep 2006

Curcumin useful in the fight against colorectal cancer

Looking for a cancer cure? Try the spice rack. In the last few years, that tactic has proved productive for researchers investigating turmeric, a curry spice used for centuries in Indian traditional medicine.

19 Sep 2006

The B7 family of co-regulatory ligands is implicated again in the pathogenesis of renal cell carcinoma progression

Previous reports from the group at Mayo Clinic have demonstrated that B7-H1 expression by renal cell carcinoma (RCC) is a marker of poor prognosis in both localized and metastatic RCC.

6 Sep 2006

Newly discovered molecular motor helps a cell determine which way is up

The sense of top and bottom is often lost in cells that become cancerous and may be an important factor in metastasis.

30 Aug 2006

Intermittent androgen deprivation in biochemical recurrence of prostate cancer after radiotherapy

Intermittent androgen deprivation (IAD) is commonly used in the treatment of CaP, which theoretically may delay the development of hormone resistance.

17 Aug 2006

Study: Collecting duct carcinoma

Collecting duct carcinoma is a rare and highly aggressive variant of renal cell carcinoma that frequently presents with advanced disease, has few effective treatment options, and is associated with a poor prognosis.

17 Aug 2006

Aggressive melanoma cells secrete Nodal - protein critical to embryo formation

A Northwestern University research group has discovered that aggressive melanoma cells secrete Nodal, a protein that is critical to proper embryo formation.

6 Aug 2006

3D model reveals secrets of metastasis

A cancer cell breaks away from a primary tumor and settles in a new location, where it once again divides.

12 Jul 2006

Yttrium-90 to control hepatocarcinoma

The University Hospital at the University of Navarra is the only centre throughout the entire Spanish state for the treatment of liver tumours by means of radioembolisation and the one with the greatest accumulated experiences in the treatment throughout Europe.

10 Jul 2006

Parameters associated with patient outcomes in lymph node positive prostate cancer

Dr. Hofer and colleagues report in the June issue of Urology that lymphovascular invasion (LVI) and the nuclear grade of the primary prostate tumor are independent predictors of PSA recurrence in men with lymph node positive CaP.

3 Jul 2006

Intermittent androgen deprivation in biochemical recurrence of prostate cancer after radiotherapy

Intermittent androgen deprivation (IAD) is commonly used in the treatment of CaP, which theoretically may delay the development of hormone resistance.

29 Jun 2006

Obesity associated with less favorable outcome after radiation therapy for prostate cancer

Obese men with prostate cancer are at higher risk for treatment failure after primary radiation therapy, according to a new study.

27 Jun 2006

Few well performed studies address management of lymph node positive prostate cancer

Dr. Gregory Swanson and associates from the University of Texas, San Antonio Health Science Center reviews the data for various treatment options in patients with lymph node positive prostate cancer (CaP).

27 Jun 2006

Gleevec strangles drug-resistant, metastatic prostate cancer

A medication used to treat other types of cancer strangles drug-resistant, metastatic prostate cancer by cutting off its blood supply, researchers from The University of Texas M. D. Anderson Cancer Center report in the June 7 issue of the Journal of the National Cancer Institute.

7 Jun 2006

Plasminogen activator inhibitor type 2 may play role in infection and dry eye

Plasminogen Activator Inhibitor Type 2 (PAI-2), a protein found in various cell types including the skin, has been discovered in the tissue covering the eye and may have future clinical implications in various pathologies of the ocular surface such as eye infection or dry eye.

17 May 2006

Chemotherapy regimen predicts steatohepatitis and an increase in 90-day mortality after surgery for hepatic colorectal metastases

Patients and their physicians should be careful when selecting a chemotherapy drug to treat colorectal cancer that has spread to the liver, say researchers at The University of Texas M. D. Anderson Cancer Center in Houston.

3 May 2006

Cause and treatment for aggressive head and neck cancer may have been found

Researchers report that they have found a potential molecular cause for the aggressive growth and spread of human head and neck squamous cell carcinoma, a highly malignant form of cancer with a very high death rate.

26 Apr 2006

Metastasis News and Research

Further Reading

Gene expression and lung cancer prognosis

Lab-on-a-chip nanoscale array monitors cellular processes

New technique detects signature of metastasizing melanoma with as few as 10 cancer cells present in blood sample

p120 catenin protein can stop metastasis or promote it

Curcumin useful in the fight against colorectal cancer

The B7 family of co-regulatory ligands is implicated again in the pathogenesis of renal cell carcinoma progression

Newly discovered molecular motor helps a cell determine which way is up

Intermittent androgen deprivation in biochemical recurrence of prostate cancer after radiotherapy

Study: Collecting duct carcinoma

Aggressive melanoma cells secrete Nodal - protein critical to embryo formation

3D model reveals secrets of metastasis

Yttrium-90 to control hepatocarcinoma

Parameters associated with patient outcomes in lymph node positive prostate cancer

Intermittent androgen deprivation in biochemical recurrence of prostate cancer after radiotherapy

Obesity associated with less favorable outcome after radiation therapy for prostate cancer

Few well performed studies address management of lymph node positive prostate cancer

Gleevec strangles drug-resistant, metastatic prostate cancer

Plasminogen activator inhibitor type 2 may play role in infection and dry eye

Chemotherapy regimen predicts steatohepatitis and an increase in 90-day mortality after surgery for hepatic colorectal metastases

Cause and treatment for aggressive head and neck cancer may have been found

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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