Protein C News and Research

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Research could pave way for new generation of painkillers

An international group of scientists led by Dr Nikita Gamper of the University's Faculty of Biological Sciences has discovered how two proteins play a key role in the way we feel pain, offering new targets on which drug development can be focused.

25 Mar 2010

Cardiologist receives grant to study impact of erectile dysfunction drugs on muscular dystrophy patients

A Cedars-Sinai Heart Institute cardiologist has been awarded a three-year, nearly $1 million grant from the Muscular Dystrophy Association (MDA) to study whether drugs used to treat erectile dysfunction could also be used to improve muscle blood flow and reduce fatigue in muscular dystrophy patients.

25 Mar 2010

Anesthesia can increase behavioral changes, risk of developing Alzheimer's disease

The use of repetitive anesthesia with isoflurane (one of the most common anesthetics by inhalation) increases the risk of developing changes similar to those observed in AD brains in mice with mutations of the amyloid precursor protein (APP). This is the main conclusion of Spanish researchers coordinated by Doctors Maria -ngeles Mena and Justo Garc-a de Y-benes, from CIBERNED (Centro de Investigaci-n Biom-dica en Red de Enfermedades Neurodegenerativas).

25 Mar 2010

Experimental vaccine can help delay IBD and colon cancer

An experimental vaccine against an abnormal protein found in some tumors has the potential to delay the onset of inflammatory bowel disease (IBD) and in turn prevent progression to colon cancer, according to researchers at the University of Pittsburgh School of Medicine.

25 Mar 2010

Canadian Diabetes Association launches new tools to help optimize diabetes care

Today the Canadian Diabetes Association launched new tools for people living with diabetes and healthcare practitioners to help optimize diabetes care across the country.

25 Mar 2010

New series of filters screen compounds for drug development

The identification of compounds that could be promising candidates for drug development has become easier following research by the Walter and Eliza Hall Institute's medicinal chemistry group.

25 Mar 2010

Study: MetAP inhibitors prevent TB growth in test tubes

Suspecting that a particular protein in tuberculosis was likely to be vital to the bacteria's survival, Johns Hopkins scientists screened 175,000 small chemical compounds and identified a potent class of compounds that selectively slows down this protein's activity and, in a test tube, blocks TB growth, demonstrating that the protein is indeed a vulnerable target.

25 Mar 2010

PPD introduces comprehensive laboratory services for vaccine and biologic drug development

PPD, Inc. (Nasdaq: PPDI) today announced it is launching the PPD Vaccines & Biologics Center of Excellence, a first-in-kind comprehensive network of integrated, world-class laboratory services focused specifically on vaccine and biologic drug development.

24 Mar 2010

Pfizer to supply pneumococcal conjugate vaccines for infants and children

Pfizer Inc. today announced it has signed a 10-year Provisional Supply Agreement to supply Prevenar 13* (Pneumococcal Polysaccharide Conjugate Vaccine [13-valent, adsorbed]), the company’s 13-valent pneumococcal conjugate vaccine, for infants and young children in the world’s poorest countries under the terms of the Advance Market Commitment (AMC) pilot project against pneumococcal disease.

24 Mar 2010

Elderly patients with moderate sleep apnea live longer than their counterparts, says study

Findings from the Technion-Israel Institute of Technology could provide good news for elderly patients who suffer from sleep apnea. The research results from Prof. Peretz Lavie and Dr. Lena Lavie of the Faculty of Medicine show that elderly patients with moderate sleep apnea live longer than their counterparts in the general population.

24 Mar 2010

Complete structure of Insulin receptor discovered - may assist in drug development for diabetes

Insulin is one of the most commonly used therapeutic agents used in diabetes. While the structure of this complex protein has been studied in detail there were parts of the receptor for insulin that were not clearly defined till now. This receptor is a protein that exists on the surfaces of cells and binds to the insulin molecule. These receptors are responsible for the action of insulin on the cells.

24 Mar 2010

Protein deficiency in Down syndrome patients could contribute to cognitive impairment and congenital heart defects

Conventional wisdom among scientists for years has suggested that because individuals with Down syndrome have an extra chromosome, the disorder most likely results from the presence of too many genes or proteins contained in that additional structure.

24 Mar 2010

Renowned leaders to discuss latest findings in early-stage drug development for cancer

When people think of cancer treatment, chemotherapy infusions, injections and pills often come to mind. These treatments result from extensive research and testing in drug development. But how does the process begin?

24 Mar 2010

Inhibitex announces net loss of $4.7M for fourth-quarter 2009

Inhibitex, Inc. today announced its financial results for the fourth quarter and year ended December 31, 2009 and provided an update on various corporate developments.

23 Mar 2010

Study: Replacing dietary saturated fats with polyunsaturated fatty acids reduces coronary heart disease

A study in this week's PLoS Medicine shows that the replacement of dietary saturated fatty acids with polyunsaturated fatty acids reduces coronary heart disease events, bringing much needed scientific evidence to an issue debated by experts and clinical guidelines.

23 Mar 2010

Labeling calories on menus mandatory – unhealthy eating discouraged further

With the newly passed healthcare bill calorie counts at fast food and chain restaurants become mandatory. More than 200,000 fast food and other chain restaurants will have to include calorie counts on menus, menu boards, buffets, vending machines, alcoholic drink menus and even drive-throughs.

23 Mar 2010

Treating RNA segment in wounds may increase protein levels for growth of skin cells

Scientists have determined that chronic wounds might have trouble healing because of the actions of a tiny piece of a molecular structure in cells known as RNA.

23 Mar 2010

Blocking Bak inhibitors can be promising strategy in limiting resistance of cancer to TRAIL

The TRAIL ligand is a promising anticancer agent that preferentially kills tumor cells without apparent damage to healthy cells. Many cancers exhibit resistance to TRAIL, however, thus limiting its therapeutic potential.

23 Mar 2010

Walnuts affect genes related to prostate tumor growth: Study

Walnut consumption slows the growth of prostate cancer in mice and has beneficial effects on multiple genes related to the control of tumor growth and metabolism, UC Davis and the U.S. Department of Agriculture Western Regional Research Center in Albany, Calif. have found.

23 Mar 2010

Ultraviolet portion of sunlight may play bigger role in controlling MS: Study

For more than 30 years, scientists have known that multiple sclerosis (MS) is much more common in higher latitudes than in the tropics. Because sunlight is more abundant near the equator, many researchers have wondered if the high levels of vitamin D engendered by sunlight could explain this unusual pattern of prevalence.

23 Mar 2010

Protein C News and Research

Research could pave way for new generation of painkillers

Cardiologist receives grant to study impact of erectile dysfunction drugs on muscular dystrophy patients

Anesthesia can increase behavioral changes, risk of developing Alzheimer's disease

Experimental vaccine can help delay IBD and colon cancer

Canadian Diabetes Association launches new tools to help optimize diabetes care

New series of filters screen compounds for drug development

Study: MetAP inhibitors prevent TB growth in test tubes

PPD introduces comprehensive laboratory services for vaccine and biologic drug development

Pfizer to supply pneumococcal conjugate vaccines for infants and children

Elderly patients with moderate sleep apnea live longer than their counterparts, says study

Complete structure of Insulin receptor discovered - may assist in drug development for diabetes

Protein deficiency in Down syndrome patients could contribute to cognitive impairment and congenital heart defects

Renowned leaders to discuss latest findings in early-stage drug development for cancer

Inhibitex announces net loss of $4.7M for fourth-quarter 2009

Study: Replacing dietary saturated fats with polyunsaturated fatty acids reduces coronary heart disease

Labeling calories on menus mandatory – unhealthy eating discouraged further

Treating RNA segment in wounds may increase protein levels for growth of skin cells

Blocking Bak inhibitors can be promising strategy in limiting resistance of cancer to TRAIL

Walnuts affect genes related to prostate tumor growth: Study

Ultraviolet portion of sunlight may play bigger role in controlling MS: Study

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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