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China Nepstar Chain Drugstore first quarter revenue increases 9.0% to US$94.4 million

China Nepstar Chain Drugstore Ltd., the largest retail drugstore chain in China based on the number of directly operated stores, today announced its unaudited financial results for the first quarter ended March 31, 2011.

25 May 2011

Elan, Proteostasis create innovative drug discovery initiative for neurodegenerative disorders

Proteostasis Therapeutics and Elan Corporation today announced a strategic business relationship to advance Proteostasis' platform for the discovery and development of disease-modifying, small molecule drugs and diagnostics for the treatment of neurodegenerative disorders such as Parkinson's, Huntington's, multiple sclerosis and amyotrophic lateral sclerosis, and a broad array of dementia-related diseases including Alzheimer's.

25 May 2011

Evotec, PsychoGenics partner to offer integrated CNS drug discovery solutions

PsychoGenics Inc. today announced that it has entered into a strategic alliance with Evotec AG to provide integrated CNS drug discovery solutions to pharmaceutical and biotech companies.

25 May 2011

Study provides insight into effective treatments for autism spectrum disorder, seizures

Roughly 25-35% of individuals with autism eventually develop seizures and many of the remainder have subclinical seizure-like brain activity. However, little is known about which traditional epilepsy treatments and commonly used non-traditional alternative treatments are effective for treating seizures or epilepsy in children and adults with autism spectrum disorder.

25 May 2011

New clinical research study to compare two medications for bipolar disorder

Patients with bipolar disorder may be eligible for a new clinical research study comparing two medications -- quetiapine, a widely prescribed second-generation antipsychotic mood-stabilizing medication, and lithium, the gold-standard mood stabilizer.

25 May 2011

Leukemia protein plays a role in Alzheimer's disease

After decades of studying the pathological process that wipes out large volumes of memory, scientists at The Feinstein Institute for Medical Research discovered a molecule called c-Abl that has a known role in leukemia also has a hand in Alzheimer's disease.

25 May 2011

Positive interim results from new bladder cancer therapy trial

Clinical trials for a new bladder cancer therapy show promising interim results. Lead researcher Alvaro Morales says that the breakthrough using the drug Urocidin follows thirty years of his research in this important area.

25 May 2011

New combination therapy eradicates acute lymphoblastic leukemia in children, older adults

In a significant breakthrough, investigators at Weill Cornell Medical College and the University of California, San Francisco, have been able to overcome resistance of a form of leukemia to targeted therapy, demonstrating complete eradication of the cancer in cell and animal studies.

25 May 2011

Disaster-response planning raises challenges for mental health services, bioethicists say

Johns Hopkins University bioethicists say disaster-response planning has generally overlooked the special needs of people who suffer from pre-existing and serious mental conditions.

24 May 2011

New study finds drug's side effect labeling have ballooned in size

The lists of potential side effects that accompany prescription drugs have ballooned in size, averaging 70 reactions per drug, a number that can overwhelm physicians trying to select suitable treatments for their patients, according to a new study of drug labels.

24 May 2011

Scientific evidence supports benefits of sunscreen usage to prevent skin cancer

The American Academy of Dermatology today reiterated the safety and effectiveness of sunscreens to protect against the damaging effects from exposure to ultraviolet (UV) radiation. As one component of a daily sun-protection strategy, sunscreen is an important tool in the fight against skin cancer, including melanoma, the deadliest form of skin cancer.

24 May 2011

NIAID team completes analysis of most proteins produced by elephantiasis parasite worm

A team led by Thomas B. Nutman, M.D., of the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, has completed a large-scale analysis of most of the proteins produced by Brugia malayi, one kind of parasitic worm that causes lymphatic filariasis, or elephantiasis.

24 May 2011

Researchers replicate progression of inflammatory gene changes of kidney from mild to severe diabetic nephropathy

University of Louisville researchers have replicated the inflammatory gene changes of a human kidney as it progresses from mild to severe diabetic nephropathy, using a mouse model developed by a UofL researcher, according to an article published today in the journal Experimental Nephrology. Diabetic nephropathy is the foremost cause of kidney failure.

24 May 2011

Novel hepatitis C-like virus discovered in dogs

In a study to be published online this week in the Proceedings of the National Academy of Sciences, researchers report the discovery of a novel hepatitis C-like virus in dogs. The identification and characterization of this virus gives scientists new insights into how hepatitis C in humans may have evolved and provides scientists renewed hope to develop a model system to study how it causes disease.

24 May 2011

IPS examines subsidized malaria drugs in Kenya

Inter Press Service looks at the roll out of the Affordable Medicines Facility-malaria in Kenya. The program, which is managed by the Global Fund to Fight AIDS, Tuberculosis and Malaria, makes subsidized malaria medications available through private pharmacies in seven other pilot countries - Cambodia, Ghana, Madagascar, Niger, Nigeria, Tanzania and Uganda.

24 May 2011

Scientists discover genetic regions that affect severity of cystic fibrosis

A team of international researchers, including Case Western Reserve University School of Medicine, have discovered regions of the genome that affect the severity of the genetic disease cystic fibrosis, the most common lethal genetic disease affecting children in North America.

24 May 2011

'Survival protein' protects brain against effects of stroke

Johns Hopkins scientists say that a newly discovered "survival protein" protects the brain against the effects of stroke in rodent brain tissue by interfering with a particular kind of cell death that's also implicated in complications from diabetes and heart attack.

24 May 2011

Long-term, regular acetaminophen use may be associated with lower prostate cancer risk

A new study from American Cancer Society researchers finds use of 30 tablets a month or more of acetaminophen for five or more years was associated with an estimated 38% lower risk of prostate cancer. The study appears in Cancer Epidemiology, Biomarkers and Prevention and is one of only two studies of prostate cancer to date that have examined the association with acetaminophen use that was both long-term and regular.

24 May 2011

Vertex Incivek receives FDA approval for treatment of chronic hepatitis C

The U.S. Food and Drug Administration today approved Incivek treat certain adults with chronic hepatitis C infection. Incivek is used for patients who have either not received interferon-based drug therapy for their infection or who have not responded adequately to prior therapies. Incivek is approved for use with interferon therapy made up of peginterferon alfa and ribavirin.

24 May 2011

Infertility centers under scrutiny

Private infertility treatment centers in Britain are set to come under increased scrutiny. These centers have come under scrutiny for exploiting vulnerable couples with their high fees and exaggerated success story claims.

23 May 2011

Drugs News and Research

China Nepstar Chain Drugstore first quarter revenue increases 9.0% to US$94.4 million

Elan, Proteostasis create innovative drug discovery initiative for neurodegenerative disorders

Evotec, PsychoGenics partner to offer integrated CNS drug discovery solutions

Study provides insight into effective treatments for autism spectrum disorder, seizures

New clinical research study to compare two medications for bipolar disorder

Leukemia protein plays a role in Alzheimer's disease

Positive interim results from new bladder cancer therapy trial

New combination therapy eradicates acute lymphoblastic leukemia in children, older adults

Disaster-response planning raises challenges for mental health services, bioethicists say

New study finds drug's side effect labeling have ballooned in size

Scientific evidence supports benefits of sunscreen usage to prevent skin cancer

NIAID team completes analysis of most proteins produced by elephantiasis parasite worm

Researchers replicate progression of inflammatory gene changes of kidney from mild to severe diabetic nephropathy

Novel hepatitis C-like virus discovered in dogs

IPS examines subsidized malaria drugs in Kenya

Scientists discover genetic regions that affect severity of cystic fibrosis

'Survival protein' protects brain against effects of stroke

Long-term, regular acetaminophen use may be associated with lower prostate cancer risk

Vertex Incivek receives FDA approval for treatment of chronic hepatitis C

Infertility centers under scrutiny

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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