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Researchers highlight gene loss as potential process of genetic change, evolutionary adaption

"Loss is nothing else but change and change is nature's delight" says the quote by the philosopher and emperor Marcus Aurelius, which opens the scientific article that analyses the gene loss phenomenon and its impact on the evolution of living beings.

16 Jun 2016

PharmaMar announces initiation of pivotal plitidepsin clinical trial in patients with T-cell lymphomas

PharmaMar today announced the start of a multicenter, prospective, pivotal study to analyze the efficacy of the antitumoral compound of marine origin, plitidepsin in patients with relapsed and refractory angioimmunoblastic T-cell lymphoma.

15 Jun 2016

FDG-PET imaging tracks ability of atezolizumab to bolster immunity against NSCLC

Non-small cell lung cancers have a collective reputation for not responding very well to chemotherapy. Researchers at the 2016 Annual Meeting of the Society of Nuclear Medicine and Molecular Imaging (SNMMI) are presenting a means of evaluating an immunotherapy that fights off NSCLC by strengthening a patient's own immune system.

14 Jun 2016

Molecular imaging technique could help optimize radiotherapy dose to combat NETs

Aggressive neuroendocrine cancer is something of a dark horse--a rare, elusive and persevering force linked to discouraging long-term survival rates.

14 Jun 2016

New imaging study links tau proteins to neurodegenerative pathology of Alzheimer's disease

Alzheimer's is a devastating and incurable disease marked by beta-amyloid and tau protein aggregations in the brain, yet the direct relationship between these proteins and neurodegeneration has remained a mystery.

14 Jun 2016

RNA editing enzyme ADAR1 may play role in regeneration of leukemia stem cells

Cancer stem cells are like zombies — even after a tumor is destroyed, they can keep coming back. These cells have an unlimited capacity to regenerate themselves, making more cancer stem cells and more tumors.

10 Jun 2016

Natural material in plants can enhance performance of sunscreens

Warm weather means beach vacations and pool-dipping for many of us. It also signals a season of slathering on sunscreen to avoid getting burned. Someday, those products could be enhanced with lignin, a natural material in plants and a major waste product of the paper industry.

9 Jun 2016

NMR-based metabolomics: an interview with Prof. Claudio Luchinat

Professor Claudio Luchinat, University of Florence and co-founder of the Magnetic Resonance Center (CERM), speaks to News-Medical about his research in NMR-based metabolomics.

From Bruker BioSpin Division 9 Jun 2016

Researchers identify promising new compound for targeting triple-negative breast cancer

Researchers at the University of Michigan have identified a promising new compound for targeting one of the most aggressive types of breast cancer.

9 Jun 2016

Study provides new insights into development of skin-depigmenting disease vitiligo

Researchers at the University of Bonn and the Ludwig-Maximilians-Universität of Munich have decoded a new mechanism of how the immune system can specifically attack pigmented cells of the skin.

8 Jun 2016

Common angina drug can stimulate patient's own white blood cells to combat cryptococcosis

A drug, more commonly used in the treatment of angina, could be the focus of a new strategy in fighting the fatal fungal infection cryptococcosis

8 Jun 2016

Tarantula venom could help provide relief for patients suffering from Irritable Bowel Syndrome

Researchers from The University of Adelaide in South Australia found that a specific peptide in the spider venom could be used to understand how people sense pain.

7 Jun 2016

UZH scientists identify new class of protein compounds to treat HER2-positive breast cancer

In Switzerland alone, more than 5,700 women are diagnosed with breast cancer each year, and almost 1,400 of those affected die of the disease. In many very invasive forms of breast cancer, the cells have too much of the receptor HER2 on their surface.

3 Jun 2016

New treatment shows promise against hard-to-treat eye cancer

Eye cancer took the life of author and neurologist Oliver Sacks last year, bringing attention to the rare and deadly disease. Scientists have tried to develop precision treatments against cancers like this one, but the mutations that cause them have proven difficult to block with drugs.

3 Jun 2016

Fasnall drug appears to inhibit tumor growth by promoting cancer cell death

A promising new compound appears to impede a process that fuels breast cancer in mice, a discovery that could have implications in the treatment of a host of cancers.

3 Jun 2016

New drugs show promise as first antidote for radiation exposure

University of Virginia School of Medicine researchers have identified promising drugs that could lead to the first antidote for radiation exposure that might result from a dirty bomb terror attack or a nuclear accident such as Chernobyl.

2 Jun 2016

Duke scientists discover new small-molecule drugs to treat chronic pain

A research team at Duke University has discovered a potential new class of small-molecule drugs that simultaneously block two sought-after targets in the treatment of pain.

1 Jun 2016

Toxic substance acrolein may play role in preventing fibrillation linked to Alzheimer's disease

Scientists from RIKEN in Japan have discovered that acrolein—a toxic substance produced in cells during times of oxidative stress—in fact may play a role in preventing the process of fibrillation, an abnormal clumping of peptides that has been associated with Alzheimer's disease and other neural diseases.

1 Jun 2016

TSRI scientists develop first drug candidate that neutralizes disease-causing RNA repeats

In an important new study with implications for the treatment of dozens of incurable diseases, scientists from the Florida campus of The Scripps Research Institute have for the first time created a drug candidate that attacks and neutralizes the RNA structure that causes an incurable progressive, inherited disease involving a gradual loss of control over body movement.

1 Jun 2016

Study provides new insights into molecular basis of CaSR-related human diseases

A study led by researchers at Georgia State University provides new insights into the molecular basis of human diseases resulting from mutations in the calcium-sensing receptor (CaSR), a protein found in cell membranes.

1 Jun 2016

Compound News and Research

Researchers highlight gene loss as potential process of genetic change, evolutionary adaption

PharmaMar announces initiation of pivotal plitidepsin clinical trial in patients with T-cell lymphomas

FDG-PET imaging tracks ability of atezolizumab to bolster immunity against NSCLC

Molecular imaging technique could help optimize radiotherapy dose to combat NETs

New imaging study links tau proteins to neurodegenerative pathology of Alzheimer's disease

RNA editing enzyme ADAR1 may play role in regeneration of leukemia stem cells

Natural material in plants can enhance performance of sunscreens

NMR-based metabolomics: an interview with Prof. Claudio Luchinat

Researchers identify promising new compound for targeting triple-negative breast cancer

Study provides new insights into development of skin-depigmenting disease vitiligo

Common angina drug can stimulate patient's own white blood cells to combat cryptococcosis

Tarantula venom could help provide relief for patients suffering from Irritable Bowel Syndrome

UZH scientists identify new class of protein compounds to treat HER2-positive breast cancer

New treatment shows promise against hard-to-treat eye cancer

Fasnall drug appears to inhibit tumor growth by promoting cancer cell death

New drugs show promise as first antidote for radiation exposure

Duke scientists discover new small-molecule drugs to treat chronic pain

Toxic substance acrolein may play role in preventing fibrillation linked to Alzheimer's disease

TSRI scientists develop first drug candidate that neutralizes disease-causing RNA repeats

Study provides new insights into molecular basis of CaSR-related human diseases

Advancing therapeutic biopolymer development eBook

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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