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HSV-1 infection induces strain-specific transcriptional differences in infected neurons

Why do some people with cold sores around their lips experience painful lesions, while others have no symptoms at all, yet still spread the virus? A new study conducted at Penn State finds that these differences could be due to variations in the way certain strains of herpes simplex (HSV-1) -- the virus that causes cold sores, as well as genital herpes -- activate gene expression in neurons.

29 Mar 2021

Type 2 diabetes drug can successfully reduce symptoms associated with tuberous sclerosis complex

A team of researchers led by UCL Great Ormond Street Institute of Child Health and Great Ormond Street Hospital (GOSH) has found that metformin - a drug commonly used to treat Type 2 diabetes - can successfully reduce symptoms associated with tuberous sclerosis complex (TSC), including reduction in the frequency of seizures and the size of brain tumors.

29 Mar 2021

COVID-19 long haulers report persistent neurological symptoms

Researchers at Northwestern University, USA, analyzed "long hauler" patients whose symptoms lasted at least six weeks. They found persistent neurological symptoms, including brain fog and headache.

26 Mar 2021

Researchers use new process to improve deep brain stimulation

Despite having remarkable utility in treating movement disorders such as Parkinson's disease, deep brain stimulation (DBS) has confounded researchers, with a general lack of understanding of why it works at some frequencies and does not at others.

26 Mar 2021

FDA approves new indication for drug to treat pediatric NDO patients

Today, the U.S. Food and Drug Administration approved a new indication for Myrbetriq (mirabegron extended-release tablets) and Myrbetriq Granules (mirabegron for extended-release oral suspension) to treat neurogenic detrusor overactivity (NDO), a bladder dysfunction related to neurological impairment, in children ages three years and older.

25 Mar 2021

Frequent consumption of outside meals linked to all-cause mortality

Dining out is a popular activity worldwide, but there has been little research into its association with health outcomes. Investigators looked at the association between eating out and risk of death and concluded that eating out very frequently is significantly associated with an increased risk of all-cause death, which warrants further investigation.

25 Mar 2021

Study provides better understanding of how Hurricane Harvey mobilized harmful pollutants

The unprecedented rainfall from Hurricane Harvey in 2017 brought more than flood damage to southeast Texas.

24 Mar 2021

Modeling study predicts SARS-CoV-2 variants with high receptor binding affinity

A new study adds to the sum of knowledge about SARS-CoV-2, with respect to its natural and biologically significant mutations, using computational modeling of the virus-receptor interactions. Understanding how viral mutations affect the virus-host interactions is crucial for shaping proper strategies to control the virus.

24 Mar 2021

How do fingerprints enhance our sense of touch?

Dr. Ewa Jarocka speaks to News-Medical about our senses, and how fingerprints can enhance our sense of touch.

24 Mar 2021

Checkpoint inhibition could offer an effective treatment option for patients with rare cancer

Peritoneal mesothelioma is cancer that develops in the lining of the abdomen, which is known as the peritoneum.

24 Mar 2021

Artificial neural network for automatically decoding and interpreting cortical signals

Russian scientists have proposed a new algorithm for automatic decoding and interpreting the decoder weights, which can be used both in brain-computer interfaces and in fundamental research. The results of the study were published in the Journal of Neural Engineering.

23 Mar 2021

Genetic study identifies sex-dependent differences in major psychiatric disorders

An analysis of sex differences in the genetics of schizophrenia, bipolar disorder and major depressive disorders indicates that while there is substantial genetic overlap between males and females, there are noticeable sex-dependent differences in how genes related to the central nervous system, immune system, and blood vessels affect people with these disorders.

23 Mar 2021

Consumption of ultra-processed foods and drinks could raise colorectal cancer risk

Consumption of ultra-processed foods and drink could increase the risk of developing colorectal cancer. This was the conclusion of a large study undertaken by the Barcelona Institute for Global Health, a center supported by the "la Caixa" Foundation, based on questionnaires about food behaviors completed by around 8,000 people in Spain.

23 Mar 2021

COVID-19 lockdown restrictions reduced light activity related to socializing and work

A study which looked at activity levels before and during the COVID-19 pandemic has found lockdown restrictions significantly reduced light activity associated with socializing and work.

22 Mar 2021

Drinking electrolytes instead of water can help prevent muscle cramps

If you reach for water when a muscle cramp strikes, you might want to think again. New research from Edith Cowan University has revealed drinking electrolytes instead of pure water can help prevent muscle cramps.

18 Mar 2021

Study investigates how genetic variants contribute to increased risk of lung cancer

Lung cancer is the leading cause of cancer death in the U.S. for both men and women. While risk for this disease can be influenced by environmental and lifestyle factors like smoking, studies estimate that 18% of lung cancer cases are due to inherited genetic variants.

18 Mar 2021

Frequency News and Research

HSV-1 infection induces strain-specific transcriptional differences in infected neurons

Type 2 diabetes drug can successfully reduce symptoms associated with tuberous sclerosis complex

COVID-19 long haulers report persistent neurological symptoms

Researchers use new process to improve deep brain stimulation

FDA approves new indication for drug to treat pediatric NDO patients

Frequent consumption of outside meals linked to all-cause mortality

Study provides better understanding of how Hurricane Harvey mobilized harmful pollutants

Modeling study predicts SARS-CoV-2 variants with high receptor binding affinity

How do fingerprints enhance our sense of touch?

Checkpoint inhibition could offer an effective treatment option for patients with rare cancer

Artificial neural network for automatically decoding and interpreting cortical signals

Genetic study identifies sex-dependent differences in major psychiatric disorders

Consumption of ultra-processed foods and drinks could raise colorectal cancer risk

COVID-19 lockdown restrictions reduced light activity related to socializing and work

Drinking electrolytes instead of water can help prevent muscle cramps

Study investigates how genetic variants contribute to increased risk of lung cancer

Rumination syndrome often confused with other gastrointestinal conditions

Coronaviruses may be vulnerable to ultrasound vibrations, study suggests

COVID-19 is more difficult to diagnose in children and adolescents, finds study

Study evaluates effectiveness of hormone therapies in managing postmenopausal nocturia

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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