Hormones News and Research

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IRCM geneticists discover an unsuspected organization of pituitary cells

A team of geneticists at the Institut de recherches cliniques de Montr-al (IRCM), directed by Dr. Jacques Drouin, made an unexpected discovery on hormone secretion. Contrary to common belief, the researchers found that pituitary cells are organized in structured networks. The scientific breakthrough was published yesterday by the scientific journal Proceedings of the National Academy of Sciences.

28 Jul 2011

Scientists reveal complete three-dimensional atomic structure of an activated GPCR

G protein-coupled receptors (GPCRs) are popular drug targets, accounting for about one-third of approved drugs and many hundreds of drugs currently in development. They act as molecular switches that transduce extracellular signals by activating heterotrimeric G proteins located at the inside of the cell.

27 Jul 2011

Male sex hormones can protect men from inflammatory diseases

It's all down to the testosterone: men are usually more muscular than women, they have deeper voices and more body hair. And - men are less susceptible to inflammatory diseases and allergies than women. This is also due to the male sex hormones as pharmacists at the Friedrich Schiller University Jena have shown in a recent study.

27 Jul 2011

Hormone therapy may be hazardous in men with pre-existing heart conditions

Adding hormone therapy to radiation therapy has been proven in randomized clinical trials to improve overall survival for men with intermediate- and high-risk prostate cancer. However, adding hormone therapy may reduce overall survival in men with pre-existing heart conditions, even if they have high-risk prostate cancer according to a new study just published online in advance of print in the International Journal of Radiation Oncology·Biology·Physics, the official scientific journal of ASTRO.

26 Jul 2011

Late-stage prostate tumors are driven by different hormonal pathway

UT Southwestern Medical Center researchers have narrowed the potential drug targets for advanced prostate cancer by demonstrating that late-stage tumors are driven by a different hormonal pathway than was thought previously.

26 Jul 2011

Takeda resubmits alogliptin and fixed-dose combination therapy NDA to FDA

Takeda Pharmaceutical Company Limited announced today that Takeda Global Research & Development Center, Inc., resubmitted two New Drug Applications to the United States Food and Drug Administration for alogliptin and the fixed-dose combination therapy alogliptin/pioglitazone, which combines alogliptin with pioglitazone in a single tablet.

26 Jul 2011

IAS conference concludes with positive news on HIV prevention

"Scientists on Wednesday wrapped up their biggest forum in the 30-year history of AIDS, unveiling stunning weapons to prevent the spread of HIV," Agence France-Presse reports about the 6th International AIDS Society Conference on HIV Pathogenesis, Treatment and Prevention in Rome.

22 Jul 2011

Taller women more prone to cancer: Study

New research has shown that taller women could be more prone to suffering from cancer. The British study published online in the medical journal The Lancet on Thursday said cancer risk rose about 16% for every 4-inch rise in height. Increasing height heightened the chances of cancers of breast, ovary, womb, bowel, leukemia and malignant melanoma (skin cancer) the study found.

21 Jul 2011

Babies of stressed pregnant mums may have lasting effects

According to a new study high levels of stress during pregnancy can cause an unborn child to have lifelong mental scars. Researchers have found that a mother facing unnecessary crises can leave an imprint in the brains of her children, making them less able to cope as they get older.

20 Jul 2011

Study reveals how alcohol and weight influence breast cancer hormone levels in post menopausal women

Weight is the biggest factor affecting the level of sex hormones that increase breast cancer risk in post menopausal women, according to new research published in the British Journal of Cancer today (Wednesday).

20 Jul 2011

Birth control pills may reduce woman's bone density

Birth control pills may reduce a woman's bone density, according to a study published online July 13 in The Journal of Clinical Endocrinology and Metabolism by Group Health Research Institute (GHRI) scientists.

20 Jul 2011

Scientists discover cholesterol moves far slower within and between cells

Neutrons have shown the movement of cholesterol between and within cells takes far longer than previously thought. Findings could impact the treatment of a range of diseases linked to abnormal rates of cholesterol transfer.

19 Jul 2011

Anti-malaria drug provides key insight into potential treatments for autoimmune diseases

In a study published recently in the journal Science Signaling Van Andel Research Institute (VARI) scientists demonstrate on the molecular level how the anti-malaria drug chloroquine represses inflammation, which may provide a blueprint for new strategies for treating inflammation and a multitude of autoimmune diseases such as arthritis, multiple sclerosis, and certain cancers.

19 Jul 2011

Top-ranking male baboons exhibit higher levels of stress hormones

Ecologists at Princeton University recently discovered top-ranking male baboons exhibit higher levels of stress hormones than second-ranking males, suggesting that being at the top of a social hierarchy may be more costly than previously thought.

16 Jul 2011

Female teens more vulnerable to negative effects of binge drinking

Binge or "heavy episodic" drinking is prevalent during adolescence, raising concerns about alcohol's effects on crucial neuromaturational processes during this developmental period.

16 Jul 2011

Study sheds light on the way antibodies distinguish between different 'biomarkers'

A new research paper sheds light on the way antibodies distinguish between different but closely related 'biomarkers' - proteins which reveal information about the condition of the human body.

15 Jul 2011

Men with early-stage prostate cancer can benefit from short-term ADT, radiation therapy

Short-term hormone therapy given in combination with radiation therapy for men with early-stage prostate cancer increases their chance of living longer and not dying from the disease, compared with that of those who receive the same radiation therapy alone, according to a Radiation Therapy Oncology Group (RTOG) study published in the July 14 issue of the New England Journal of Medicine.

14 Jul 2011

Reproductive steroids may play a role in occurrence of generalized tonic-clonic seizures in women

A recent multi-center study determined that women with generalized tonic-clonic seizures (GTCS) had a greater number of seizures during anovulatory cycles-menstrual cycles where an egg is not released-than in cycles where ovulation occurs. According to the study publishing today in Epilepsia, a journal of the International League Against Epilepsy (ILAE), reproductive steroids may play a role in GTCS occurrence.

14 Jul 2011

Both body and brain mechanisms are involved in effects of exercise to modulate food intake

Research to be presented at the upcoming annual meeting of the Society for the Study of Ingestive Behavior (SSIB), the foremost society for research into all aspects of eating and drinking behavior, finds that alterations of meal-related gut hormone signals may contribute to the overall effects of exercise to help manage body weight.

13 Jul 2011

Study confirms link between phthalates and thyroid hormone levels in humans

A link between chemicals called phthalates and thyroid hormone levels was confirmed by the University of Michigan in the first large-scale and nationally representative study of phthalates and BPA in relation to thyroid function in humans.

12 Jul 2011

Hormones News and Research

IRCM geneticists discover an unsuspected organization of pituitary cells

Scientists reveal complete three-dimensional atomic structure of an activated GPCR

Male sex hormones can protect men from inflammatory diseases

Hormone therapy may be hazardous in men with pre-existing heart conditions

Late-stage prostate tumors are driven by different hormonal pathway

Takeda resubmits alogliptin and fixed-dose combination therapy NDA to FDA

IAS conference concludes with positive news on HIV prevention

Taller women more prone to cancer: Study

Babies of stressed pregnant mums may have lasting effects

Study reveals how alcohol and weight influence breast cancer hormone levels in post menopausal women

Birth control pills may reduce woman's bone density

Scientists discover cholesterol moves far slower within and between cells

Anti-malaria drug provides key insight into potential treatments for autoimmune diseases

Top-ranking male baboons exhibit higher levels of stress hormones

Female teens more vulnerable to negative effects of binge drinking

Study sheds light on the way antibodies distinguish between different 'biomarkers'

Men with early-stage prostate cancer can benefit from short-term ADT, radiation therapy

Reproductive steroids may play a role in occurrence of generalized tonic-clonic seizures in women

Both body and brain mechanisms are involved in effects of exercise to modulate food intake

Study confirms link between phthalates and thyroid hormone levels in humans

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