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Tibotec begins enrollment in TMC435 phase 3 trial for treatment of HCV

Medivir AB, the emerging research-based specialty pharmaceutical company focused on infectious diseases, notes that its development partner, Tibotec Pharmaceuticals, announced today that the global phase 3 studies with TMC435 in treatment-naive patients and patients who have relapsed after prior SOC treatment have started.

18 Feb 2011

ASTRO develops radiation therapy guideline for treating bone metastases

The American Society for Radiation Oncology Clinical Affairs and Quality Committee has developed a guideline for the use of radiation therapy in treating bone metastases. The guideline will be published in the International Journal of Radiation Oncology-Biology-Physics, an official journal of ASTRO.

17 Feb 2011

Two researchers receive Brupbacher Prize for Cancer Research 2011

Today, the Charles Rodolphe Brupbacher Prize for Cancer Research 2011 goes to two researchers who have contributed to better understanding of the genetics underlying the growth of tumors.

17 Feb 2011

PMC to sponsor UCLA Seminar on Lung-Sparing Therapies for Malignant Pleural Mesothelioma

The Pacific Meso Center at The Pacific Heart, Lung, & Blood Institute is pleased to announce that it has agreed to help sponsor a UCLA Seminar on Lung-Sparing Therapies for Malignant Pleural Mesothelioma, an asbestos-related cancer involving the lining of the chest.

17 Feb 2011

Cook Medical launches new histology needle for endoscopic ultrasound

A new histology needle for endoscopic ultrasound (EUS) from Cook Medical is now on the market, giving physicians the ability to retrieve tissue samples from hard-to-reach regions within or adjacent to the GI tract with a minimally invasive procedure.

17 Feb 2011

Astellas, AVEO enter development, commercialization agreement for tivozanib

Astellas Pharma Inc., a global pharmaceutical company, and AVEO Pharmaceuticals, Inc. today announced that they have entered into a worldwide agreement outside of Asia to develop and commercialize tivozanib, AVEO's lead product candidate designed to optimally block the VEGF pathway by inhibiting all three VEGF receptors, for the treatment of a broad range of cancers.

17 Feb 2011

Scientists to present research on RMI ability to classify lung, kidney tumors at USCAP meeting

Clinical researchers from Cornell Weil Medical School and University of Chicago Medical School will present research conducted on Raman Molecular Imaging's ability to differentiate diagnostic dilemmas in lung and kidney tumors at the United States and Canadian Academy of Pathology's 100th Annual Meeting, Feb. 26-March 4 at the Henry B. Gonzalez Convention Center, San Antonio, Texas.

16 Feb 2011

Combined chemotherapy and radiation therapy effective against Hodgkin's lymphoma, in the short term

Modern treatment for early stage Hodgkin's lymphoma is highly effective, leaving most patients with no evidence of cancer. However, experts differ on the best approach: Is chemotherapy enough or does adding radiation therapy improve the outcome?

16 Feb 2011

Presence of jumping genes, amplified oncogenes may be key to tumor progression: Researchers

The Massachusetts General Hospital research team that first discovered tumor-associated RNA in tiny membrane-enclosed sacs released into the bloodstream by cancer cells has now found that these microvesicles also contain segments of tumor DNA, including retrotransposons - also called "jumping genes" - that copy and insert themselves into other areas of the genome.

10 Feb 2011

Study finds link between sleep duration and colorectal adenomas

An inadequate amount of sleep has been associated with higher risks of obesity, heart disease, diabetes, and death. Now colon cancer can be added to the list.

9 Feb 2011

Cancer can give important clues about nature and history of life

Despite decades of research and billions of dollars, cancer remains a major killer, with an uncanny ability to evade both the body's defenses and medical intervention. Now an Arizona State University scientist believes he has an explanation.

8 Feb 2011

Study: Fluorescent probe may serve as useful tool in future surgeries to repair injured nerves

Accidental damage to thin or buried nerves during surgery can have severe consequences, from chronic pain to permanent paralysis. Scientists at the University of California, San Diego School of Medicine may have found a remedy: injectable fluorescent peptides that cause hard-to-see peripheral nerves to glow, alerting surgeons to their location even before the nerves are encountered.

6 Feb 2011

Amgen, Pfizer present Enbrel new trial results against psoriasis at 69th AAD meeting in New Orleans, LA

Amgen and Pfizer Inc. today announced results from a new trial that demonstrated Enbrel significantly improved scalp involvement in adult patients with moderate to severe plaque psoriasis, compared with placebo. The data will be presented today at the 69th Annual American Academy of Dermatology meeting in New Orleans, La.

5 Feb 2011

Research unmasks long sought stem cell origin of carcinoma

A constellation of different stem cell populations within our skin help it to cope with normal wear and tear. By constantly proliferating, the stem cells allow skin to replenish itself, allowing each cell to be replaced by a new one about once a month. But the normal cycle of division and death within one or more of these stem cell types can sometimes be derailed by genetic mishaps. Such events are believed to spawn carcinomas and other deadly skin cancers, which are the mostly frequently diagnosed cancers in the United States.

4 Feb 2011

Scientists unravel mystery about how new tumors in individuals with breast cancer take root

In a discovery that may lead to a new treatment for breast cancer that has spread to the bone, a Princeton University research team has unraveled a mystery about how these tumors take root.

4 Feb 2011

Scientists challenged to sequence genome and RNA content derived from single cancer cell

Life Technologies Corporation today announced that the Life Grand Challenges Contest, initially introduced in December 2010, is expanding to include a fourth challenge. This latest contest challenges scientists to sequence the genome and all RNA content derived from a single cancer cell using the 5500 Series SOLiD™ Sequencers.

3 Feb 2011

Targeted delivery combination crosses brain protecting barrier and homes in on tumors

A targeted delivery combination selectively crosses the tight barrier that protects the brain from the bloodstream to home in on and bind to brain tumors, a research team led by scientists from The University of Texas MD Anderson Cancer Center reported in the January issue of the Journal of Clinical Investigation.

2 Feb 2011

Octreotide inhibits HepG2 proliferation, study confirms

Hepatocellular carcinoma (HCC) is the fifth most common malignancy in the world and is estimated to cause approximately half a million deaths annually. Undoubtedly, the best available treatment for all liver tumors is complete surgical resection. However, the synthetic somatostatin analogue octreotide has been found effective in inhibiting tumor growth in a variety of experimental models. It has been reported that octreotide inhibits the proliferation and induces apoptosis of different HCC cell lines in vitro.

1 Feb 2011

Novel personalized therapy could treat metastatic melanoma and metastatic synovial cell sarcoma

Researchers have found that a novel form of personalized therapy that genetically engineers a patient's own anti-tumor immune cells to fight tumors could treat metastatic melanoma and metastatic synovial cell sarcoma, representing a potentially new therapeutic approach against these and other cancers.

1 Feb 2011

Researchers to develop computer-assisted diagnosis tools for pathologists

Researchers are leveraging Ohio Supercomputer Center resources to develop computer-assisted diagnosis tools that will provide pathologists grading Follicular Lymphoma samples with quicker, more consistently accurate diagnoses.

31 Jan 2011

Malignant News and Research

Tibotec begins enrollment in TMC435 phase 3 trial for treatment of HCV

ASTRO develops radiation therapy guideline for treating bone metastases

Two researchers receive Brupbacher Prize for Cancer Research 2011

PMC to sponsor UCLA Seminar on Lung-Sparing Therapies for Malignant Pleural Mesothelioma

Cook Medical launches new histology needle for endoscopic ultrasound

Astellas, AVEO enter development, commercialization agreement for tivozanib

Scientists to present research on RMI ability to classify lung, kidney tumors at USCAP meeting

Combined chemotherapy and radiation therapy effective against Hodgkin's lymphoma, in the short term

Presence of jumping genes, amplified oncogenes may be key to tumor progression: Researchers

Study finds link between sleep duration and colorectal adenomas

Cancer can give important clues about nature and history of life

Study: Fluorescent probe may serve as useful tool in future surgeries to repair injured nerves

Amgen, Pfizer present Enbrel new trial results against psoriasis at 69th AAD meeting in New Orleans, LA

Research unmasks long sought stem cell origin of carcinoma

Scientists unravel mystery about how new tumors in individuals with breast cancer take root

Scientists challenged to sequence genome and RNA content derived from single cancer cell

Targeted delivery combination crosses brain protecting barrier and homes in on tumors

Octreotide inhibits HepG2 proliferation, study confirms

Novel personalized therapy could treat metastatic melanoma and metastatic synovial cell sarcoma

Researchers to develop computer-assisted diagnosis tools for pathologists

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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