Stem Cells News and Research

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Stem cells have the remarkable potential to develop into many different cell types in the body during early life and growth. In addition, in many tissues they serve as a sort of internal repair system, dividing essentially without limit to replenish other cells as long as the person or animal is still alive. When a stem cell divides, each new cell has the potential either to remain a stem cell or become another type of cell with a more specialized function, such as a muscle cell, a red blood cell, or a brain cell.

Human iPS cell-derived inner ear cells may improve hereditary hearing loss

A Japanese research group has successfully grafted human iPS cell-derived inner ear cells that express human-derived proteins into the inner ears of embryonic mice.

8 Feb 2018

Study finds new stem cell pathway that allows triple-negative breast cancer to thrive

Cleveland Clinic researchers have published findings in Nature Communications on a new stem cell pathway that allows a highly aggressive form of breast cancer - triple-negative breast cancer - to thrive.

8 Feb 2018

Researchers discover molecule that enhances cartilage regeneration and curbs inflammation

Will there come a time when a patient with arthritis can forgo joint replacement surgery in favor of a shot? Keck School of Medicine of USC scientist Denis Evseenko, MD, PhD, has reason to be optimistic.

7 Feb 2018

USC scientists uncover cellular mechanism responsible for ALS and frontotemporal dementia

Scientists have for the first time discovered a mechanism that limits the number of "cellular janitors" in the nervous system, leading to increased risk for two neurodegenerative diseases: amyotrophic lateral sclerosis and frontotemporal dementia, according to a Keck School of Medicine of USC study published today in Nature Medicine.

7 Feb 2018

New CRISPR gene-editing technique can correct majority of mutations that cause DMD

Scientists have developed a CRISPR gene-editing technique that can potentially correct a majority of the 3,000 mutations that cause Duchenne muscular dystrophy (DMD) by making a single cut at strategic points along the patient's DNA, according to a study from UT Southwestern Medical Center.

6 Feb 2018

Revolutionary technology could radically change cryopreservation of cells and tissues

Everyone knows that freezing things is an imperfect process. Take frozen food, for example - most have experienced those frozen ice crystals that change the texture and taste of their favorite meal.

6 Feb 2018

CHLA participates in clinical trial using stem cells to treat rare congenital heart defect

Children's Hospital Los Angeles is announcing participation in the first-ever clinical trial using stem cells from umbilical cord blood to delay or even prevent heart failure in children born with a rare congenital heart defect that leaves them with half a heart.

5 Feb 2018

Researchers devise strategies to target glioma stem cells that could improve patient survival

Glioblastoma multiforme is the most common and aggressive primary brain tumor and has one of the worst survival rates of all cancers.

5 Feb 2018

Moffitt study identifies new drug target that may reduce GVHD risk

Stem cell transplants can cure patients with high-risk leukemia or lymphoma. Graft-versus-host disease is a potentially life-threatening side effect that occurs when the donor's immune cells attack the recipient's normal tissues.

5 Feb 2018

Ribosomes found to be cause of somatic cell pluripotency

In 2012, a Japanese research group discovered that human skin cells acquire pluripotency when introduced to lactic acid bacteria. Now, the same group of researchers have found that the cause of somatic cell conversion into pluripotent stem cells is the ribosome, a protein synthesizing cellular organelle.

5 Feb 2018

Researchers discover gene network that regulates the motor neuron development in growing embryo

UCLA researchers have discovered the inner workings of a gene network that regulates the development of spinal motor neurons in the growing chicken and mouse embryo.

2 Feb 2018

Higher susceptibility of some babies to Zika virus has a genetic origin, study shows

Microcephaly, brain calcification, skeletal alterations, auditory and visual deficits - these are examples of the damage that can be caused by Zika virus in babies born to mothers infected during pregnancy.

2 Feb 2018

Researchers identify cause of severe genetic disease

Mutations in the p63 protein lead to a number of disorders, but none is as severe as the AEC syndrome. Scientists at Goethe University Frankfurt in collaboration with a research group from the University of Naples Federico II have now discovered that this syndrome resembles diseases such as Alzheimer's, Parkinson's or ALS more closely than it does other p63-based syndromes.

2 Feb 2018

Fight for Sight awards new grants for 13 vital eye research projects

Fight for Sight, the leading eye research charity, has awarded grants totaling over £180,000 for thirteen vital research projects in partnership with nine different organizations.

2 Feb 2018

Study unravels developmental splicing program that promotes neuronal maturation

Neurons, or nerve cells, in the brain communicate with each other by transmitting electric signals, or firing action potentials, through long processes named axons (which send out signals) and dendrites (which receive signals).

1 Feb 2018

Neurons get stretches of orderly drumroll-like rumblings speckled with strong impulses

A neuron firing deep in the brain might sound a little like: Drumroll...cymbal crash! Drumroll...cymbal crash! Repeat. With emphasis on "repeat," according to a new study.

1 Feb 2018

Study identifies new potential target for treatment of blood disorders

UCLA researchers, in collaboration with the University of Iowa, discovered the contribution of a specific gene in the proper development of blood cells that give rise to hematopoietic stem cells.

1 Feb 2018

Houston Methodist researchers have new explanation for why airways close during asthma attacks

Houston Methodist researchers have a new explanation for what causes the lungs' airways to close during asthma attacks.

31 Jan 2018

Scientists discover role of two specific HOX genes in colon cancer development

In breakthrough colon cancer research, scientists at Christiana Care Health System's Center for Translational Cancer Research of the Helen F. Graham Cancer Center & Research Institute have discovered that over-expression of HOXA4 and HOXA9 genes in colon cancer stem cells promotes cell replication and contributes to the overpopulation of stem cells that drives colon cancer development.

31 Jan 2018

Scientists gain better understanding of how the intestine repairs itself after injury

Researchers at Baylor College of Medicine, Johns Hopkins University School of Medicine and the University of California, San Francisco have gained new insights into how the small intestine, one of the fastest renewing tissues in the human body, repairs itself after injury caused by intestinal rotavirus infection.

30 Jan 2018

Stem Cells News and Research

Further Reading

Human iPS cell-derived inner ear cells may improve hereditary hearing loss

Study finds new stem cell pathway that allows triple-negative breast cancer to thrive

Researchers discover molecule that enhances cartilage regeneration and curbs inflammation

USC scientists uncover cellular mechanism responsible for ALS and frontotemporal dementia

New CRISPR gene-editing technique can correct majority of mutations that cause DMD

Revolutionary technology could radically change cryopreservation of cells and tissues

CHLA participates in clinical trial using stem cells to treat rare congenital heart defect

Researchers devise strategies to target glioma stem cells that could improve patient survival

Moffitt study identifies new drug target that may reduce GVHD risk

Ribosomes found to be cause of somatic cell pluripotency

Researchers discover gene network that regulates the motor neuron development in growing embryo

Higher susceptibility of some babies to Zika virus has a genetic origin, study shows

Researchers identify cause of severe genetic disease

Fight for Sight awards new grants for 13 vital eye research projects

Study unravels developmental splicing program that promotes neuronal maturation

Neurons get stretches of orderly drumroll-like rumblings speckled with strong impulses

Study identifies new potential target for treatment of blood disorders

Houston Methodist researchers have new explanation for why airways close during asthma attacks

Scientists discover role of two specific HOX genes in colon cancer development

Scientists gain better understanding of how the intestine repairs itself after injury

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