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MIT engineers discover way to grow liver-like cells to test potential malaria drugs

In 2008, the World Health Organization announced a global effort to eradicate malaria, which kills about 800,000 people every year. As part of that goal, scientists are trying to develop new drugs that target the malaria parasite during the stage when it infects the human liver, which is crucial because some strains of malaria can lie dormant in the liver for several years before flaring up.

6 Feb 2015

New study links cell communication pathway to common brain tumors found in children

A new study by Johns Hopkins researchers links a well-known cell communication pathway called Notch to one of the most common -- but overall still rare -- brain tumors found in children.

6 Feb 2015

Half of people in the UK will develop cancer, says new estimate

One in two people will develop cancer in their lifetime, according to new calculations from Cancer Research UK.

5 Feb 2015

Newly found protein in naked mole rat helps ward off cancer

A protein newly found in the naked mole rat may help explain its unique ability to ward off cancer.

5 Feb 2015

Retigabine drug could reduce debilitating impact of strokes

New research suggests that an already-approved drug could dramatically reduce the debilitating impact of strokes, which affect nearly a million Americans every year.

5 Feb 2015

Antibodies used in research lab should be made by recombinant DNA technology, say authors

Antibodies are now established as therapeutics and indispensable in the research lab. In con-trast to high-quality therapeutics, commercial antibodies used in research often do not proper-ly function, as an international group of authors around Andreas Plückthun of UZH have warned.

5 Feb 2015

Researchers report that neurons in the brain are connected like a social network

Neurons in the brain are wired like a social network, report researchers from Biozentrum, University of Basel. Each nerve cell has links with many others, but the strongest bonds form between the few cells most similar to each other.

5 Feb 2015

Researchers develop tri-layered artificial blood vessels

By combining micro-imprinting and electro-spinning techniques, researchers at Shanghai University's Rapid Manufacturing Engineering Center have developed a vascular graft composed of three layers for the first time.

5 Feb 2015

Scientists investigate how T cells in colorectal tumors actively fight cancer

In recent years, a standard follow-up to colorectal cancer surgery has been to analyze the tumor tissue for the presence of immune cells. Finding high quantities of cytotoxic T cells, or "killer cells", means that there is a good chance that the disease will take a favorable course and that the risk of metastasis is comparatively low.

5 Feb 2015

Cell free DNA analysis less effective than sequential screening in finding fetal chromosomal abnormalities

In a study to be presented on Feb. 5 in an oral plenary session at 8 a.m. PST, at the Society for Maternal-Fetal Medicine's annual meeting, The Pregnancy Meeting, in San Diego, researchers will report that cell free DNA analysis is less effective than sequential screening as primary testing for fetal chromosomal abnormalities.

5 Feb 2015

Study focuses on two natural approaches to preventing breast cancer

Preventing cancer requires intimate knowledge of how cancer starts, what causes it to grow and flourish, and how to stop it in its tracks. Sometimes this comes in the form of a vaccine (the HPV vaccine for cervical and head and neck cancers), a screening (a colonoscopy for colorectal cancer) or a blood test (the PSA level test for prostate cancer).

5 Feb 2015

Novel EPR oximetry technique may help clinicians directly measure oxygen in cancer, stroke patients

A novel Electron Paramagnetic Resonance (EPR) oximetry technique will help clinicians directly measure oxygen and schedule treatments at times of high oxygen levels in cancer and stroke patients to improve outcomes, The EPR team at Dartmouth's Geisel School of Medicine has found.

5 Feb 2015

Alzheimer's brains commonly have many neurons with more DNA and genomic copies of APP gene

Scientists at The Scripps Research Institute have found diverse genomic changes in single neurons from the brains of Alzheimer's patients, pointing to an unexpected factor that may underpin the most common form of the disease.

5 Feb 2015

Johns Hopkins researchers reveal that e-cigarettes weaken immune system

In a study with mice, Johns Hopkins Bloomberg School of Public Health researchers have found that e-cigarettes compromise the immune system in the lungs and generate some of the same potentially dangerous chemicals found in traditional nicotine cigarettes.

5 Feb 2015

Researchers develop smartphone accessory for rapid diagnosis of infectious diseases at point of care

A team of researchers, led by Samuel K. Sia, associate professor of biomedical engineering at Columbia Engineering, has developed a low-cost smartphone accessory that can perform a point-of-care test that simultaneously detects three infectious disease markers from a finger prick of blood in just 15 minutes.

5 Feb 2015

Research findings demonstrate new approach to transform behavior of tumor cells

Inserting a specific strain of bacteria into the microenvironment of aggressive ovarian cancer transforms the behavior of tumor cells from suppression to immunostimulation, researchers at Norris Cotton Cancer Center and the Geisel School of Medicine at Dartmouth have found.

5 Feb 2015

New studies show that treating infertility with stem cells may not be realised

Whether or not infertility can be treated with stem cells has been a matter of debate for many years.

5 Feb 2015

Three Keck Medicine scientists of USC receive $4.3 million from CIRM for stem cell research

Three scientists from Keck Medicine of the University of Southern California have won grants exceeding $4.3 million from the California Institute for Regenerative Medicine for research that includes creating a temporary liver for transplant patients, finding novel ways to treat immune disorders and blood diseases and developing a new animal model for exploring diseases like heart failure, diabetes and neurodegenerative diseases.

5 Feb 2015

Genomics of papillary thyroid carcinoma (PTC): an interview with Professor Thomas J. Giordano

There are two types of thyroid cells and therefore there are two broad types of thyroid cancer. Medullary carcinoma is derived from parafollicular or C cells, whereas follicular cells give rise to several types of thyroid cancers.

4 Feb 2015

FDA accepts Sangamo BioSciences' IND for SB-BCLmR-HSPC genome editing approach

Sangamo BioSciences, Inc. announced today that an Investigational New Drug (IND) application for the company's SB-BCLmR-HSPC genome editing approach, which is designed to provide a one-time lasting therapy for beta-thalassemia, has been accepted by the U.S. Food and Drug Administration and is now active.

4 Feb 2015

B Cell News and Research

MIT engineers discover way to grow liver-like cells to test potential malaria drugs

New study links cell communication pathway to common brain tumors found in children

Half of people in the UK will develop cancer, says new estimate

Newly found protein in naked mole rat helps ward off cancer

Retigabine drug could reduce debilitating impact of strokes

Antibodies used in research lab should be made by recombinant DNA technology, say authors

Researchers report that neurons in the brain are connected like a social network

Researchers develop tri-layered artificial blood vessels

Scientists investigate how T cells in colorectal tumors actively fight cancer

Cell free DNA analysis less effective than sequential screening in finding fetal chromosomal abnormalities

Study focuses on two natural approaches to preventing breast cancer

Novel EPR oximetry technique may help clinicians directly measure oxygen in cancer, stroke patients

Alzheimer's brains commonly have many neurons with more DNA and genomic copies of APP gene

Johns Hopkins researchers reveal that e-cigarettes weaken immune system

Researchers develop smartphone accessory for rapid diagnosis of infectious diseases at point of care

Research findings demonstrate new approach to transform behavior of tumor cells

New studies show that treating infertility with stem cells may not be realised

Three Keck Medicine scientists of USC receive $4.3 million from CIRM for stem cell research

Genomics of papillary thyroid carcinoma (PTC): an interview with Professor Thomas J. Giordano

FDA accepts Sangamo BioSciences' IND for SB-BCLmR-HSPC genome editing approach

Using single B cell screening to boost antibody discovery eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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