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Machine learning algorithm predicts DNA insertion efficiency of prime editing

A new tool to predict the chances of successfully inserting a gene-edited sequence of DNA into the genome of a cell, using a technique known as prime editing, has been developed by researchers at the Wellcome Sanger Institute.

15 Feb 2023

Neuroplasticity in fighter pilots may provide insight on the effects of space travel

Understanding the effects of space travel will help us to plan long-haul space flights, but getting access to astronauts is not easy. A new study investigates whether F16 fighter pilots demonstrate brain connectivity changes that could be expected in astronauts, based on similar exposure to changes in g-forces.

15 Feb 2023

Natural decline in insulin resistance during mid-adolescence may stop, reverse arterial stiffness progression

Significant physiologic decrease in insulin resistance during mid-adolescence may stop and reverse arterial stiffness progression, a paper published in the American Journal of Physiology-Endocrinology and Metabolism concludes.

15 Feb 2023

Red, purple and blue pigments in plants can reduce the risk of diabetes

Anthocyanins in plants have properties that reduce the risk of type 2 diabetes, shows a new review article from the Food Sciences unit of the University of Turku, Finland. Anthocyanins are red, purple and blue pigments found in fruits, vegetables, and tubers.

15 Feb 2023

Social and economic disadvantage may explain the higher risk of dementia in women

A large international study of dementia risk involving almost 30,000 people from 18 countries covering all six continents suggests that social and economic disadvantage may explain the higher risk of the condition in women.

15 Feb 2023

Smoking and vaping may put healthy young people at risk of severe COVID

The levels of some ADAM17 targets were elevated in the plasma of tobacco cigarette smokers as compared to non-smokers.

15 Feb 2023

Study highlights the interconnectedness of autoimmunity and cancer

In a recent study published in the journal Immunity, researchers reviewed the T cell response in cancer and autoimmunity to propose strategies for more effective immunotherapies.

15 Feb 2023

Researchers aim to better understand how myopia management strategies affect children

Researchers at Aston University specializing in myopia - or short sightedness - are starting work on a project with industry partners to better understand how myopia management strategies affect children.

15 Feb 2023

First successful correction of limb length in mouse model of autosomal dominant Robinow Syndrome

Robinow Syndrome is the best known of a set of genetic disorders that affect the growth and development of the skeletal system.

15 Feb 2023

Reduced butyrate production in the microbiome of type 2 diabetics

Researchers observe reduced levels of butyrate-producing bacteria in the microbiome of type 2 diabetics.

15 Feb 2023

COVID-19 is associated with higher diabetes and hypertension risk

In a recent study published in the journal JAMA Network Open, researchers determined new-onset diabetes, hypertension, and hyperlipidemia, all cardiometabolic disorders in adult coronavirus disease 2019 (COVID-19) patients under treatment in California, United States of America (USA) between March 2020 and June 2022.

15 Feb 2023

Delayed presentation of MIS-C following COVID-19

Researchers elucidate the pathophysiology of MIS-C and describe the probable reasons for the delayed presentation of the condition following COVID-19.

15 Feb 2023

Comparative study on retinoic acid-inducible gene-I of humans and bats

In a recent study posted to the bioRxiv* preprint server, researchers cloned and functionally characterized the virus ribonucleic acid (RNA) sensor, retinoic acid-inducible gene-I (RIG-I), from the microbat Myotis daubentonii (Yangochiroptera suborder) and the megabat Rousettus aegyptiacus (Yinpterochiroptera suborder), and compared them to the human ortholog.

15 Feb 2023