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Curcumin activates SIRT3 to protect bone structure in diabetic mice

In a new Scientific Reports study, curcumin protected bone-forming cells from high-glucose damage by activating the SIRT3/FoxO3a/NRF2 antioxidant pathway and restoring mitochondrial health. In diabetic mice, curcumin improved bone density and oxidative balance, highlighting its potential in osteoporosis prevention.

13 Aug 2025

ISSCR updates guidelines to address advances in stem cell-based embryo models

The International Society for Stem Cell Research (ISSCR) released an update of its 2021 Guidelines for Stem Cell Research and Clinical Translation today.

13 Aug 2025

New imaging technique enhances monitoring of atherosclerosis progression

Scientists at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) have shown that 18FDG-PET, an imaging technique widely used to study other conditions, can also be used to monitor atherosclerosis by measuring cellular metabolism within arterial plaques.

13 Aug 2025

New computational tool enhances CAR T cell therapy for hard-to-treat cancers

A computational approach by St. Jude Children's Research Hospital scientists promises to make designing T cell-based immunotherapies that target two cancer-related antigens at the same time far easier and faster.

13 Aug 2025

New mouse model reveals key role of osteocytes in osteogenesis imperfecta

Osteogenesis imperfecta (OI) refers to a group of rare genetic bone disorders that results in the formation of fragile bones. In patients with OI, the matrix that makes up the bone has been found to be abnormal, leading to an increased risk of fractures.

13 Aug 2025

KAIST develops platform for electrically-controlled cell signaling

Cells use various signaling molecules to regulate the nervous, immune, and vascular systems. Among these, nitric oxide (NO) and ammonia (NH₃) play important roles, but their chemical instability and gaseous nature make them difficult to generate or control externally.

13 Aug 2025

New discovery in spinal cord neurons offers hope for breathing recovery

Today about 300,000 people nationally living with a spinal cord injury and with respiratory complications being the most common cause of illness and death, according to the Christopher & Dana Reeve Foundation.

13 Aug 2025

New compound shows promise against aromatase inhibitor-resistant breast cancer

A new research paper was published in Volume 16 of Oncotarget on July 29, 2025, titled "PCAIs stimulate MAPK, PI3K/AKT pathways and ROS-Mediated apoptosis in aromatase inhibitor-resistant breast cancer cells while disrupting actin filaments and focal adhesion."

13 Aug 2025

mRNA vaccine shows potent efficacy in gastric cancer

Gastric cancer is one of the leading causes of cancer-related mortality worldwide, and peritoneal metastasis, wherein the cancer spreads to the peritoneum or the lining of the abdominal cavity, represents the most common form of recurrence after gastric cancer surgery.

13 Aug 2025

Love hormone oxytocin found to be critical for the formation of friendships

A new UC Berkeley study shows that the so-called love hormone, oxytocin, is also critical for the formation of friendships.

12 Aug 2025

Cancer cells hide inside bone marrow fibroblasts to resist treatment

In a recently published study, researchers at Fox Chase Cancer Center revealed for the first time that cancer cells can evade anti-cancer drugs by entering and surviving within bone marrow fibroblasts, a phenomenon they describe as "cell-in-cell."

12 Aug 2025

Nudibranchs (sea slugs) emerge as a promising source of cancer drugs

Researchers reviewed the antitumor potential of bioactive compounds from nudibranchs, marine mollusks that acquire or synthesize potent chemical defenses. These compounds, often sourced from their diet, show promising cancer-fighting activity through mechanisms like DNA damage, oxidative stress, and apoptosis.

12 Aug 2025

Polyphenols and exercise show promise in fighting gliomas

A new review in Food Science & Nutrition highlights how combining dietary polyphenols with structured exercise can enhance brain function, regulate epigenetics, and support glioma management. The authors outline mechanisms, patient-centered strategies, and research gaps for turning this synergy into clinical practice.

12 Aug 2025

Aging weakens blood-brain barrier and impairs memory

A new study from researchers at the University of Illinois Chicago reveals how the blood-brain barrier gets leakier with age, contributing to memory deficits.

12 Aug 2025

New method greatly improves the precision of genome editing

A research team headed by the University of Zurich has developed a powerful new method to precisely edit DNA by combining cutting-edge genetic engineering with artificial intelligence.

12 Aug 2025

Gut bacteria can digest common food thickeners

It turns out those cellulose-based thickening agents found in common foods can be digested.

12 Aug 2025

AI discovers promising antibiotic compounds in Archaea microbes

They've survived for billions of years in boiling acid, deep-sea vents and salt flats. Now, some of Earth's oldest life forms - microbes called Archaea - are offering a new weapon in the fight against one of today's most urgent health threats: antibiotic resistance.

12 Aug 2025

Adding MET inhibitor enhances immune response against small cell lung tumors

Adding a MET gene inhibitor enhances the effect of combined chemotherapy and immunotherapy in small cell lung cancer (SCLC), according to a multicenter study led by the Hospital del Mar Research Institute, in collaboration with researchers from the CIBERONC cancer research network.

12 Aug 2025

Novel vaccine shows promise against KRAS-driven pancreatic and colorectal cancers

A novel cancer vaccine that stimulates the immune system to target one of the most common cancer-driving mutations has shown encouraging early results in patients with pancreatic and colorectal cancer, two of the most difficult-to-treat malignancies, according to a study led in part by investigators at the UCLA Health Jonsson Comprehensive Cancer Center.

12 Aug 2025

Right shoring your supply chain in Life Sciences: Balancing cost, risk & resilience

Discover expert insights on right shoring supply chains in medical and life sciences. Learn how cost, risk, regionalization, and automation shape long term resilience.

From Ascential Medical & Life Sciences 12 Aug 2025