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Researchers find that protein synthesis can be studied in adult stem cells

For the first time, researchers have shown that an essential biological process known as protein synthesis can be studied in adult stem cells - something scientists have long struggled to accomplish. The groundbreaking findings from the Children's Medical Center Research Institute at UT Southwestern (CRI) also demonstrate that the precise amount of protein produced by blood-forming stem cells is crucial to their function.

10 Mar 2014

Takeda works with UCL to drive research into tackling muscle disorders

Japanese pharmaceutical company Takeda will work with University College London (UCL) to drive research into tackling muscle disorders, in particular muscular dystrophy.

10 Mar 2014

Exposure to UV light may exacerbate melanoma cells to creep outside blood vessels

Based on the pioneering work of Dr. Claire Lugassy and Dr. Raymond Barnhill at UCLA's Jonsson Comprehensive Cancer Center, a new study provides additional support for a process by which melanoma cells, a deadly form of skin cancer, can spread throughout the body by creeping like tiny spiders along the outside of blood vessels without ever entering the blood stream, and that this process is exacerbated by exposure to ultraviolet (UV) light.

10 Mar 2014

Researchers examine association between diabetes and obesity

It's by now well established that obesity is a major risk factor for diabetes. But what exactly is it about extra body fat that leads to insulin resistance and blood glucose elevation, the hallmarks of diabetes?

7 Mar 2014

Study shows how changes in organized cell membrane network of heart muscle leads to heart failure

Colchicine, a drug that's used to treat gout, has the beneficial side effect of lowering the risk of heart attack in patients taking it. Conversely, taxol, a drug for treating cancer, has the opposite effect; raising the risk of heart failure.

6 Mar 2014

Removing gut bacteria may play critical role in reducing cancer risk

Bacteria in the gut are essential for the development of intestinal tumors in mice, according to research led by investigators from the Icahn School of Medicine at Mount Sinai. Removing the bacteria may play a critical role in reducing cancer risk, the researchers write, in the March issue of the Journal of Experimental Medicine.

5 Mar 2014

New research uncovers abnormal molecular signaling pathways for kidney failure

Prevention and reversal of chronic kidney disease is an urgent public health need. The disease affects 1 in 10 Americans, is debilitating and deadly, and existing drugs, at best, offer only mild delay in progression to end-stage kidney failure.

4 Mar 2014

Photoreactive compounds open new routes to treatment of neurological diseases

Photoreactive compounds developed by scientists of Ludwig-Maximilians-Universitaet (LMU) in Munich directly modulate nerve-cell function, and open new routes to the treatment of neurological diseases, including chronic pain and certain types of visual impairment.

3 Mar 2014

Researchers discover novel treatments for psoriasis that are likely to cause fewer side effects

Almost ten years ago, the group led by Erwin Wagner, currently at the Spanish National Cancer Research Centre (CNIO), developed genetically modified mice showing symptoms very reminiscent to psoriasis.

28 Feb 2014

FSU researchers link prenatal nicotine exposure to future ADHD

Prenatal exposure to nicotine could manifest as attention deficit hyperactivity disorder in children born a generation later, according to a new study by Florida State University College of Medicine researchers.

28 Feb 2014

Study identifies enzyme with key role in precancerous lesions

Cancer of the pancreas is usually not detected until it's too late to cure. But precursor lesions that form in the pancreas and its ducts can signal the disease before it strikes, and when caught early enough, they can be prevented from progressing to become cancer.

26 Feb 2014

IRSF announces new research grants for translational research program and clinical trials

The International Rett Syndrome Foundation (IRSF) announces today ten (10) new research grants at leading global research institutions; a new Translational Research Program; and additional funding for current human clinical trials.

24 Feb 2014

Jackson Laboratory Assistant Professor wins 2013 Lewis Rudin Glaucoma Prize from NYAM

Jackson Laboratory Assistant Professor Gareth Howell, Ph.D., is one of two winners of the 2013 Lewis Rudin Glaucoma Prize from The New York Academy of Medicine.

24 Feb 2014

Researchers propose new treatment to prevent mucositis in cancer patients

Experimental work pointing to a therapy for alleviating mucositis -- a common, severe side effect of chemotherapy and irradiation of cancer patients or patients prepared for bone marrow transplantation - has been achieved by an international team of researchers from the US and Israel headed by scientists at the Hebrew University of Jerusalem.

20 Feb 2014

Cystinosis Research Foundation granted $2.15M in 2013 to researchers investigating cure for cystinosis

The Cystinosis Research Foundation awarded $2,153,048 in 2013 to researchers investigating better treatments and a cure for cystinosis, a rare metabolic and genetic disease that afflicts about 500 children and young adults in the United States and 2,000 worldwide.

19 Feb 2014

Scientists propose improved method of screening salmonella vaccines in small animal studies

An innovative vaccine technology makes use of reengineered salmonella to deliver protective immunity. If such recombinant attenuated salmonella vaccines or RASVs can be perfected, they hold the promise of safe, lost-cost, orally administered defenses against viral, bacterial, fungal and parasitic infections.

19 Feb 2014

Discovery could lead to improved early detection, prevention strategies for sudden cardiac death

UC Irvine researchers have found a specific genetic flaw that is connected to sudden death due to heart arrhythmia - a leading cause of mortality for adults around the world.

18 Feb 2014

NCKU research team identifies medicine capable of rejuvenating aged hearts

A southern Taiwan-based National Cheng Kung University (NCKU) research team has identified the critical time period and a drug as treatment for cardiac repairing, the university revealed recently at a press conference.

14 Feb 2014

First evidence of link between prenatal vitamin A deficiency and postnatal asthma

A team of Columbia University Medical Center (CUMC) investigators led by Wellington V. Cardoso, MD, PhD, has found the first direct evidence of a link between prenatal vitamin A deficiency and postnatal airway hyperresponsiveness, a hallmark of asthma.

13 Feb 2014

Researchers demonstrate new approach to treating muscular dystrophy

Researchers at Washington University School of Medicine in St. Louis have demonstrated a new approach to treating muscular dystrophy. Mice with a form of this muscle-weakening disease showed improved strength and heart function when treated with nanoparticles loaded with rapamycin, an immunosuppressive drug recently found to improve recycling of cellular waste.

12 Feb 2014

Mouse Model News and Research

Researchers find that protein synthesis can be studied in adult stem cells

Takeda works with UCL to drive research into tackling muscle disorders

Exposure to UV light may exacerbate melanoma cells to creep outside blood vessels

Researchers examine association between diabetes and obesity

Study shows how changes in organized cell membrane network of heart muscle leads to heart failure

Removing gut bacteria may play critical role in reducing cancer risk

New research uncovers abnormal molecular signaling pathways for kidney failure

Photoreactive compounds open new routes to treatment of neurological diseases

Researchers discover novel treatments for psoriasis that are likely to cause fewer side effects

FSU researchers link prenatal nicotine exposure to future ADHD

Study identifies enzyme with key role in precancerous lesions

IRSF announces new research grants for translational research program and clinical trials

Jackson Laboratory Assistant Professor wins 2013 Lewis Rudin Glaucoma Prize from NYAM

Researchers propose new treatment to prevent mucositis in cancer patients

Cystinosis Research Foundation granted $2.15M in 2013 to researchers investigating cure for cystinosis

Scientists propose improved method of screening salmonella vaccines in small animal studies

Discovery could lead to improved early detection, prevention strategies for sudden cardiac death

NCKU research team identifies medicine capable of rejuvenating aged hearts

First evidence of link between prenatal vitamin A deficiency and postnatal asthma

Researchers demonstrate new approach to treating muscular dystrophy

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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