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Postmenopausal women receiving estrogen plus progestin at increased risk of breast cancer

Researchers have identified how the hormones progesterone and estrogen interact to increase cell growth in normal mammary cells and mammary cancers, a novel finding that may explain why postmenopausal women receiving hormone replacement therapy with estrogen plus progestin are at increased risk of breast cancer.

19 Jan 2011

AMBR sensor measures growth and drug susceptibility of bacterial cells without use of microscope

With an invention that can be made from some of the same parts used in CD players, University of Michigan researchers have developed a way to measure the growth and drug susceptibility of individual bacterial cells without the use of a microscope.

19 Jan 2011

Antidepressant medication reduces frequency and severity of menopausal hot flashes

Women who were either in the transition to menopause or postmenopausal experienced a reduction in the frequency and severity of menopausal hot flashes with the use of the antidepressant medication escitalopram, compared to women who received placebo, according to a study in the January 19 issue of JAMA.

19 Jan 2011

Medtronic recieves conditional approval from FDA to modify CoreValve U.S. Pivotal Clinical Trial

Medtronic, today announced it has received conditional approval from the U.S. Food and Drug Administration to modify its CoreValve U.S. Pivotal Clinical Trial.

19 Jan 2011

Modifiable and non-modifiable lifestyle factors influence breast cancer risk

Many risk factors for breast cancer are well studied and documented. Thus, scientists are sure by now that early first menstrual period, late onset of menopause and a family history of breast cancer are associated with an increased breast cancer risk.

19 Jan 2011

Soy protein lowers total cholesterol and non-HDL: New study

Soy protein's ability to lower total and LDL cholesterol has been extensively studied, but the mechanism whereby soy protein lowers cholesterol remains unresolved. A new study published in the Journal of Clinical Lipidology last month shows that soy protein lowers total cholesterol and non-HDL cholesterol significantly more than milk protein in patients with moderately high cholesterol levels.

18 Jan 2011

New York Times examines Russia's 'inadequate fight' against HIV/AIDS

Russia's HIV/AIDS epidemic "has defied worldwide trends, expanding more rapidly year by year than almost anywhere else," the New York Times writes in an article that examines how the country has become "one of the world's low points in the effort to fight the spread of HIV," in large part due to the government's failure to reach out to injecting drug users (IDUs) and sex workers - the groups "at the heart" of the epidemic.

18 Jan 2011

BSD Medical sells MicroThermX Microwave System to Med-Italia Biomedica

BSD Medical Corporation, a leading provider of medical systems that utilize heat therapy to treat cancer, today announced the sale and shipment of the MicroThermX Microwave System to Med-Italia Biomedica (Med-Italia), one of the largest interventional radiology/oncology distributors in Italy.

18 Jan 2011

DKMA issues GMP certificate to Cambrex Zenara Indian manufacturing facility

Cambrex Corporation announced today that the Danish Medicines Agency (DKMA) has issued a Certificate of Good Manufacturing Practice (GMP) compliance for its manufacturing site in Hyderabad, India, following an audit conducted in October 2010. The DKMA Certificate is accepted by all EU Health Authorities and by authorities of several other countries that recognize EU Certification.

18 Jan 2011

New data on role of miR-34 tumor suppressor in preventing cancer stem cell development

Mirna Therapeutics, Inc., a leading developer of microRNA (miRNA)-based therapeutics, announced today the publication of new data in the journal Nature Medicine describing the role of the tumor suppressor miRNA, miR-34, in preventing cancer stem cell development. The published results reveal that miR-34 is commonly down-regulated in prostate cancer stem cells and that this down-regulation is essential for cancer stem cell viability.

18 Jan 2011

NCI sponsors fourth REOLYSIN clinical trial in pancreatic cancer

Oncolytics Biotech Inc. announced today that the Cancer Therapy Evaluation Program, Division of Cancer Treatment and Diagnosis, U.S. National Cancer Institute (NCI), which is part of the National Institutes of Health, has agreed to sponsor a 2-Arm randomized Phase II study of carboplatin, paclitaxel plus REOLYSIN® versus carboplatin and paclitaxel alone in the first line treatment of patients with recurrent or metastatic pancreatic cancer.

18 Jan 2011

Cadence launches OFIRMEV pain medication in the U.S.

Cadence Pharmaceuticals, Inc. today announced the launch of OFIRMEV™ (acetaminophen) injection, the first and only intravenous (IV) formulation of acetaminophen to be approved in the United States. The U.S. Food and Drug Administration (FDA) approved OFIRMEV in November 2010 for the management of mild to moderate pain, the management of moderate to severe pain with adjunctive opioid analgesics, and the reduction of fever.

18 Jan 2011

Critical Diagnostics' Presage ST2 Assay effectively risk-stratifies chronic heart failure patients

Critical Diagnostics, the exclusive developer of the Presage® ST2 Assay, announces the publication of the Penn Heart Failure Study (PHFS) in an advance e-publication of the January 19, 2010 edition of Circulation: Heart Failure. The results of this study demonstrated that ST2 levels not only predict outcomes for ambulatory outpatients with chronic heart failure, they more effectively risk-stratify such patients.

18 Jan 2011

Quebec reimburses VIDAZA for treatment of blood cancer

Quebec patients with serious blood cancers (intermediate-2 and high-risk myelodysplastic syndrome and acute myeloid leukemia) now have publicly funded access to a new innovative therapy, VIDAZA® (azacitidine). Following a priority review and subsequent positive recommendation from the Conseil du medicament, patients now have the potential to significantly extend survival.

18 Jan 2011

American Heart Association honors SBUMC with Get With The Guidelines-Stroke Gold Plus Performance Achievement Award

Stony Brook University Medical Center has received the 2009 American Heart Association/American Stroke Association's Get With The Guidelines Stroke Gold Plus Performance Achievement Award.

18 Jan 2011

Drug-coated stents hold promise for treatment of clogged leg arteries

Drug-coated stents hold promise as a safe and lasting solution for the treatment of clogged leg arteries, suggest two-year results of the Zilver PTX Trial being presented at the 23rd annual International Symposium on Endovascular Therapy (ISET). Blocked leg arteries are a symptom of peripheral arterial disease (PAD), which affects 8 to 12 million Americans.

18 Jan 2011

Bathing tumor-ridden livers in chemotherapy increases survival time

Bathing tumor-ridden livers in chemotherapy increases the length of time certain cancer patients survive without progression of the disease, according to Phase III trial results being presented at the 3rd annual Symposium on Clinical Interventional Oncology (CIO), in collaboration with the International Symposium on Endovascular Therapy (ISET).

18 Jan 2011

Heart disease patients' skin cells may help test long QT syndrome

Skin cells from a patient with an inherited heart disease were the seeds of a stem cell experiment that could help researchers test specific treatments for the disease, known as long QT syndrome. The research results appear in the January 16 issue of the journal Nature.

18 Jan 2011

Rotator cuff surgery does not fully restore normal shoulder motion, strength: Study

Shoulder motion after rotator cuff surgery remains significantly different when compared to the patient's opposite shoulder, according to a Henry Ford Hospital study.

18 Jan 2011

Clinical studies by expert HIV clinicians suggest that HIV-TRePS may have clinical and economic benefits

Two multinational clinical studies indicate that the RDI’s system for predicting how HIV and AIDS patients will respond to different drugs could be a useful tool with potential clinical and economic benefits. The studies, published in the January issue of AIDS Patient Care and STDs, involved highly experienced physicians in the USA, Canada and Italy who used the system to help them select the optimum combination of HIV drugs for patients whose therapy was failing.

18 Jan 2011

Therapy News and Research

Postmenopausal women receiving estrogen plus progestin at increased risk of breast cancer

AMBR sensor measures growth and drug susceptibility of bacterial cells without use of microscope

Antidepressant medication reduces frequency and severity of menopausal hot flashes

Medtronic recieves conditional approval from FDA to modify CoreValve U.S. Pivotal Clinical Trial

Modifiable and non-modifiable lifestyle factors influence breast cancer risk

Soy protein lowers total cholesterol and non-HDL: New study

New York Times examines Russia's 'inadequate fight' against HIV/AIDS

BSD Medical sells MicroThermX Microwave System to Med-Italia Biomedica

DKMA issues GMP certificate to Cambrex Zenara Indian manufacturing facility

New data on role of miR-34 tumor suppressor in preventing cancer stem cell development

NCI sponsors fourth REOLYSIN clinical trial in pancreatic cancer

Cadence launches OFIRMEV pain medication in the U.S.

Critical Diagnostics' Presage ST2 Assay effectively risk-stratifies chronic heart failure patients

Quebec reimburses VIDAZA for treatment of blood cancer

American Heart Association honors SBUMC with Get With The Guidelines-Stroke Gold Plus Performance Achievement Award

Drug-coated stents hold promise for treatment of clogged leg arteries

Bathing tumor-ridden livers in chemotherapy increases survival time

Heart disease patients' skin cells may help test long QT syndrome

Rotator cuff surgery does not fully restore normal shoulder motion, strength: Study

Clinical studies by expert HIV clinicians suggest that HIV-TRePS may have clinical and economic benefits

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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