Bone Marrow News and Research

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Bone Marrow is the soft, sponge-like tissue in the center of most bones. It produces white blood cells, red blood cells, and platelets.

Scientists develop novel treatment strategy for multiple myeloma

Scientists at Virginia Commonwealth University Massey Cancer Center have developed a novel treatment strategy for multiple myeloma that pairs two targeted agents to kill cancer cells. The study's findings, published in today's edition of the journal "Blood," are the first to demonstrate the synergistic, anti-myeloma effects of this combination regimen both in vitro and in vivo.

11 Feb 2011

First patient treated in cytomegalovirus~ACE/ASPECT Phase II randomised clinical trial

Cell Medica, a leading UK cellular therapeutics company that develops, manufactures and markets cellular immunotherapy products for the treatment of infectious disease and cancer, announces today that the first patient has been treated in the CMV~ACE/ASPECT trial at University College Hospital London.

10 Feb 2011

New rotary-powered device for bone marrow aspiration, biopsy yields superior samples with less pain

For many cancer patients, a bone marrow biopsy and/or aspiration is one of the most dreaded aspects of their diagnosis and treatment plan. The traditional method for gaining bone marrow involves grinding a needle by hand through a patient's skin and bone, and the procedure is often described as extremely painful.

10 Feb 2011

IDF commends Illinois advisory committee for unanimous vote to recommend SCID Newborn Screening

The Illinois Genetic and Metabolic Diseases Advisory Committee voted unanimously to recommend that the Department of Health screen all newborns for Severe Combined Immune Deficiency (SCID) - commonly known as bubble boy disease.

9 Feb 2011

bcl3 gene limits lung injury during acute stress from illness, trauma, transplant

Lung injury is a common cause of death among patients with pneumonia, sepsis or trauma and in those who have had lung transplants. The damage often occurs suddenly and can cause life-threatening breathing problems and rapid lung failure.

9 Feb 2011

Hematopoietic stem cells are less fixed, more flexible than previously thought: Study

The bone marrow stem cells responsible for generating new blood cells are less fixed and more flexible than previously thought, according to a paper published online on February 7 in the Journal of Experimental Medicine.

8 Feb 2011

Integra LifeSciences launches Integra Allograft Cancellous Sponge

Integra LifeSciences Holdings Corp announced today the launch of Integra Allograft Cancellous Sponge, a compressible bone graft composed of 100% cancellous bone. The sponge-like handling characteristics of Integra Allograft Cancellous Sponge allow it to absorb fluids like saline, blood or bone marrow aspirate.

7 Feb 2011

Viewpoints: Judge Vinson's decision and Sarah Palin, Voting Rights Act; States' Medicaid 'burden;' Global fund controversy

With news coverage focused on Federal District Judge Roger Vinson's decision Monday to declare the health care reform law unconstitutional, it might be easy to miss this week's news from another federal courthouse: opponents of the Voting Rights Act have renewed their efforts to have that law declared unconstitutional, too.

5 Feb 2011

U-M Medical School earns $368.7 million in NIH research funding during federal fiscal year 2010

University of Michigan Medical School physicians and scientists earned more than $368.7 million in National Institutes of Health research funding in federal fiscal year 2010, according to NIH data. In all, the School's faculty brought in $481.8 million in research funding from all sources in U-M fiscal year 2010.

5 Feb 2011

EntreMed announces publication of ENMD-2076 Phase 1 results against solid tumors in AACR journal

EntreMed, Inc., today announced the publication of key papers on the clinical and preclinical development of ENMD-2076, an Aurora A/angiogenic kinase inhibitor. The clinical data were published in the December 3, 2010 on-line issue of the American Association for Cancer Research journal, Clinical Cancer Research, and are expected to appear soon in the print version of the publication.

4 Feb 2011

Engineered cells take control of the cells and microenvironment following transplantation

In work that could jumpstart the promising field of cell therapy, in which cells are transplanted into the body to treat a variety of diseases and tissue defects, researchers at Brigham and Women's Hospital (BWH) have engineered cells that could solve one of the key challenges associated with the procedure: control of the cells and their microenvironment following transplantation.

4 Feb 2011

Lampreys may have dual immune defense system similar to that of humans

Biologists have discovered that primitive, predatory lampreys have structures within their gills that play the same role as the thymus, the organ where immune cells called T cells develop in mammals, birds and fish.

4 Feb 2011

Scientists reprogram marrow cells from patient with chronic myeloid leukemia

By coaxing healthy and diseased human bone marrow to become embryonic-like stem cells, a team of Wisconsin scientists has laid the groundwork for observing the onset of the blood cancer leukemia in the laboratory dish.

4 Feb 2011

Treg therapy ensures success of hematopoietic stem cell transplantation, without triggering GVHD

For blood cancer patients at high risk of relapse, hematopoietic stem cell transplantation (HSCT), the transplantation of blood-forming stem cells, is one of best options for treatment and a potential cure. Unfortunately, the most common complication of HSCT is graft-versus-host disease (GVHD), a serious and often deadly post-transplant complication that occurs when the newly transplanted donor cells recognize the recipient's own cells as foreign and react by attacking the cells in the patient's body.

4 Feb 2011

Stem cells delivered intranasally improve motor function in Parkinson's disease

Stem cells, delivered intranasally, were found to substantially improve motor function in Parkinson's disease in a study co-authored by William H. Frey II, Ph.D, Director of the Alzheimer's Research Center, part of HealthPartners Research Foundation. Frey collaborated with Lusine Danielyan, MD, of University Hospital of Tubingen in Germany.

4 Feb 2011

Roundup: N.Y., Texas, Calif. Medicaid plans spark protests; Conn. nursing homes; Fla. Medical Board

Gov. Andrew Cuomo's effort to strip lawmakers of power over the state's Medicaid program is facing a barrage of criticism in both houses and parties. Lawmakers on Wednesday described the governor's Medicaid proposal as an intrusion on their powers and said they would block it from becoming law.

4 Feb 2011

IDF commends Florida council for recommending SCID screening for all newborns

The Florida Genetics and Newborn Screening Program Advisory Council voted unanimously to recommend that the Department of Health screen all newborns for Severe Combined Immune Deficiency (SCID) – commonly known as bubble boy disease.

3 Feb 2011

PanCare Childhood and Adolescent Cancer Survivor Care and Follow-up Studies to kick off in Lund, Sweden

By learning more about these late effects of treatment, the health care services can, on the one hand, improve and reduce the intensity of the treatment, and, on the other hand, find appropriate ways to care for those suffering from side-effects of the treatment in adolescence and adulthood.

3 Feb 2011

Enrollment stopped in one of two global necitumumab Phase III studies in NSCLC

Eli Lilly and Company and Bristol-Myers Squibb Company announced today that they have stopped enrollment in one of their two global Phase III studies evaluating necitumumab, an investigational anti-cancer agent, as a first-line treatment for advanced non-small cell lung cancer (NSCLC).

3 Feb 2011

$FDA grants Onyx fast track designation for carfilzomib in treatment of relapsed and refractory multiple myeloma$

FDA grants Onyx fast track designation for carfilzomib in treatment of relapsed and refractory multiple myeloma

Onyx Pharmaceuticals, Inc. announced today that the U.S. Food and Drug Administration (FDA) has granted fast track designation for carfilzomib, a next generation proteasome inhibitor for the potential treatment of patients with relapsed and refractory multiple myeloma.

1 Feb 2011

Bone Marrow News and Research

Further Reading

Scientists develop novel treatment strategy for multiple myeloma

First patient treated in cytomegalovirus~ACE/ASPECT Phase II randomised clinical trial

New rotary-powered device for bone marrow aspiration, biopsy yields superior samples with less pain

IDF commends Illinois advisory committee for unanimous vote to recommend SCID Newborn Screening

bcl3 gene limits lung injury during acute stress from illness, trauma, transplant

Hematopoietic stem cells are less fixed, more flexible than previously thought: Study

Integra LifeSciences launches Integra Allograft Cancellous Sponge

Viewpoints: Judge Vinson's decision and Sarah Palin, Voting Rights Act; States' Medicaid 'burden;' Global fund controversy

U-M Medical School earns $368.7 million in NIH research funding during federal fiscal year 2010

EntreMed announces publication of ENMD-2076 Phase 1 results against solid tumors in AACR journal

Engineered cells take control of the cells and microenvironment following transplantation

Lampreys may have dual immune defense system similar to that of humans

Scientists reprogram marrow cells from patient with chronic myeloid leukemia

Treg therapy ensures success of hematopoietic stem cell transplantation, without triggering GVHD

Stem cells delivered intranasally improve motor function in Parkinson's disease

Roundup: N.Y., Texas, Calif. Medicaid plans spark protests; Conn. nursing homes; Fla. Medical Board

IDF commends Florida council for recommending SCID screening for all newborns

PanCare Childhood and Adolescent Cancer Survivor Care and Follow-up Studies to kick off in Lund, Sweden

Enrollment stopped in one of two global necitumumab Phase III studies in NSCLC

FDA grants Onyx fast track designation for carfilzomib in treatment of relapsed and refractory multiple myeloma

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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