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FDA approves Gilotrif for patients with late stage non-small cell lung cancer

Companion test also approved to identify appropriate patients The U.S. Food and Drug Administration today approved Gilotrif (afatinib) for patients with late stage (metastatic) non-small cell lung cancer (NSCLC) whose tumors express specific types of epidermal growth factor receptor (EGFR) gene mutations, as detected by an FDA-approved test. Lung cancer is the leading cause of cancer-related death among men and women.

16 Jul 2013

Researchers distinguish viral and bacterial infections in children with fever

In children with fever but no other symptoms of illness, it is difficult to know whether a child has a viral infection that will resolve on its own or a potentially serious bacterial infection that requires antibiotics.

16 Jul 2013

House Republicans, Dems spar over employer mandate delay; Senate GOP petitioning president for 'permanent delay' of Obamacare

Encouraged by the administration's delay of the employer mandate provision by one year, Republicans were active on both sides of Capitol Hill Tuesday, renewing their calls for repeal.

12 Jul 2013

Scientists set out to develop safer versions of acetaminophen

Efforts to develop a safer form of acetaminophen - the pain and fever-reducer that is one of the most widely used drugs - have led to discovery of substances that may have less potentially toxic effects on the liver. A report on the research appears in ACS Medicinal Chemistry Letters.

12 Jul 2013

Novel therapeutic approach prevents dengue virus replication by artificial microRNAs

Mosquito-borne dengue viruses cause an estimated 50 million cases of human dengue fever a year and are a significant public health threat worldwide. A novel therapeutic approach prevents dengue virus from reproducing in humans by targeting and silencing key regions of the dengue genome essential for viral replication.

12 Jul 2013

Phase III study: REVLIMID meets primary endpoint in patients newly diagnosed with multiple myeloma

Celgene International Sàrl, a wholly-owned subsidiary of Celgene Corporation, today announced that its phase III study (MM-020/IFM 07-01) of REVLIMID (lenalidomide) in combination with dexamethasone in patients newly diagnosed with multiple myeloma met its primary endpoint of progression-free survival.

11 Jul 2013

Many pediatricians underuse interpreters to improve care of children, families with limited English

U.S. pediatricians are not using trained language interpreters as often as they should, despite evidence that such services are vital to improving the care of children and families with limited English, according to findings from research conducted jointly by the Johns Hopkins Children's Center and the American Academy of Pediatrics.

11 Jul 2013

Tips to keep kids safe during hot weather

Several US states and cities have seen record breaking temperatures this summer. Doctors at Cincinnati Children's Hospital Medical Center want to give tips to parents and guardians on how they can keep their kids safe during the hot weather.

11 Jul 2013

Study identifies new groups of people at risk of parasitic lung infection

A study conducted by Dr. James Diaz, Professor of Public Health and Preventive Medicine and Program Director of the Environmental/Occupational Health Sciences Program at the LSU Health Sciences Center New Orleans School of Public Health, analyzed cases of a parasitic lung infection and found new modes of transmission and associated behaviors, identifying new groups of people at risk.

11 Jul 2013

Pfizer's Prevenar 13 receives European approval to include adults for prevention of invasive disease

Pfizer Inc. announced today the company's pneumococcal conjugate vaccine, Prevenar 13 (pneumococcal polysaccharide conjugate vaccine [13-valent, adsorbed]), received European approval for an expanded indication to include adults aged 18 to 49 years for active immunization for the prevention of invasive disease caused by vaccine-type Streptococcus pneumoniae (S. pneumoniae).

10 Jul 2013

Research findings provide pediatric dentists, parents with new information on dental sedation

Research led by Priyanshi Ritwik, DDS, MS, LSUHSC Associate Professor of Pediatric Dentistry at LSU Health Sciences Center New Orleans, reports important findings about side effects and how long they linger after discharge of common oral drugs used to sedate some children during dental procedures.

9 Jul 2013

Young patient survives deadly virus with minimal neurological deficits

Rhode Island Hospital successfully treated a 21-year-old patient with severe neuroinvasive Eastern Equine Encephalitis (EEE), minimizing neurological deficits and resulting in a very positive outcome. The findings from this treatment are published online in advance of print in the journal Neurocritical Care.

9 Jul 2013

Discovery of new receptor could turn the tide against mosquitoes' growing advantage

In the global war against disease-carrying mosquitoes, scientists have long believed that a single molecular door was the key target for insecticide. This door, however, is closing, giving mosquitoes the upper hand.

9 Jul 2013

Researchers study existence of cross-protection between multiple strains of infectious disease

Using a unique data set spanning 40 years of dengue fever incidence in Thailand, an international team led by biostatistician Nicholas Reich at the University of Massachusetts Amherst has for the first time estimated from data that after an initial dengue infection, a person is protected from infection with other strains for between one and three years.

3 Jul 2013

Researchers discover role of TonB bacterial protein that causes various diseases

A Kansas State University-led study has discovered the role of a protein in bacteria that cause a wide variety of diseases, including typhoid fever, plague, meningitis and dysentery. The results may lead to new and improved antibiotics for humans and animals.

2 Jul 2013

Study describes radiologic findings in H7N9 pneumonia

H7N9 pneumonia is characterized by imaging findings that differentiate it from other types of pneumonia, including rapidly progressive changes in the lungs and pulmonary connective tissues, according to the first study to describe radiologic findings in the disease. The results are published online in the journal Radiology.

2 Jul 2013

Genentech's Perjeta regimen gets FDA Priority Review for HER2-positive early stage breast cancer

Genentech, a member of the Roche Group, today announced that the U.S. Food and Drug Administration has accepted the company's supplemental Biologics License Application for the use of a Perjeta (pertuzumab) regimen before surgery (neoadjuvant treatment) in people with HER2-positive early stage breast cancer.

2 Jul 2013

NanoViricides submits letter of intent to file Orphan Drug Application with EMA for DengueCide

NanoViricides, Inc. announced today that it has submitted its letter of intent to file an Orphan Drug Application with the European Medicines Agency for DengueCide, its drug candidate for the treatment of dengue and dengue hemorrhagic fever.

1 Jul 2013

Test-based approach of WHO unsuitable for regions where lot of malaria occurs: Research

In view of the sharp rise in treatment costs of malaria, the World Health Organization says that there must be a hard diagnosis before the disease is treated.

29 Jun 2013

Ecology, evolution of infectious diseases to be highlighted at ESA's annual meeting

West Nile virus, Lyme disease and hantavirus. All are infectious diseases spreading in animals and in people. Is human interaction with the environment somehow responsible for the increase in these diseases? The ecology and evolution of infectious diseases will be highlighted at two symposia at the Ecological Society of America's annual meeting, held from Aug. 5-9 in Minneapolis, Minn.

29 Jun 2013

Fever News and Research

FDA approves Gilotrif for patients with late stage non-small cell lung cancer

Researchers distinguish viral and bacterial infections in children with fever

House Republicans, Dems spar over employer mandate delay; Senate GOP petitioning president for 'permanent delay' of Obamacare

Scientists set out to develop safer versions of acetaminophen

Novel therapeutic approach prevents dengue virus replication by artificial microRNAs

Phase III study: REVLIMID meets primary endpoint in patients newly diagnosed with multiple myeloma

Many pediatricians underuse interpreters to improve care of children, families with limited English

Tips to keep kids safe during hot weather

Study identifies new groups of people at risk of parasitic lung infection

Pfizer's Prevenar 13 receives European approval to include adults for prevention of invasive disease

Research findings provide pediatric dentists, parents with new information on dental sedation

Young patient survives deadly virus with minimal neurological deficits

Discovery of new receptor could turn the tide against mosquitoes' growing advantage

Researchers study existence of cross-protection between multiple strains of infectious disease

Researchers discover role of TonB bacterial protein that causes various diseases

Study describes radiologic findings in H7N9 pneumonia

Genentech's Perjeta regimen gets FDA Priority Review for HER2-positive early stage breast cancer

NanoViricides submits letter of intent to file Orphan Drug Application with EMA for DengueCide

Test-based approach of WHO unsuitable for regions where lot of malaria occurs: Research

Ecology, evolution of infectious diseases to be highlighted at ESA's annual meeting

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Why use light scattering to analyze proteins and viral vectors?

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