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Researchers use genomic techniques to show why different strains of Salmonella infect particular animal species

It's called bird flu for a reason. Particular characteristics about the influenza virus known as H5N1 allow it to primarily affect avifauna, though in some worrying cases the disease has been passed to humans.

3 Nov 2015

Small subtype of immune cells appears to prevent obesity

We tend to think of the immune system as guarding us against bacteria, viruses and assorted foreign invaders, but this system has some other surprising roles. Weizmann Institute researchers have now identified a small subtype of immune cells that appears to prevent metabolic syndrome: obesity, high blood pressure, and high levels of blood sugar and cholesterol.

3 Nov 2015

Griffith University uncovers first 3-D image of protein linked to cancer spread

Griffith University's Institute for Glycomics has made scientific history by determining the first three-dimensional image of a protein linked to the spread of cancer.

3 Nov 2015

Researchers identify tumor suppressor genes that drive subset of melanomas

Of the hundreds of genes that can be mutated in a single case of melanoma, only a handful may be true "drivers" of cancer. In research that appeared today in Nature Genetics, a Weizmann Institute of Science team has now revealed one of the drivers of a particularly deadly subset of melanomas - one that is still seeing a rise in new cases. This gene is a newly identified member of a group of genes called tumor suppressor genes.

3 Nov 2015

Findings provide a step towards personalized cancer therapy

Oxford University researchers have found the Achilles heel of certain cancer cells - mutations in a gene called SETD2. Their findings will be presented to the National Cancer Research Institute conference in Liverpool this Monday (2 Nov 15).

2 Nov 2015

Diet rich in soy protein and isoflavones can protect menopausal women from osteoporosis

Eating a diet rich in both soy protein and isoflavones can protect menopausal women from bone weakening and osteoporosis, according to the results of a preliminary study presented today at the Society for Endocrinology annual conference in Edinburgh.

2 Nov 2015

Key protein controls stem cell properties that could make them useful in regenerative medicine

A key protein controls stem cell properties that could make them more useful in regenerative medicine, according to a study led by Mount Sinai researchers and published online today in the journal Cell Stem Cell.

31 Oct 2015

Researchers develop more accurate method of imprinting proteins

It will be increasingly difficult for protein molecules to remain anonymous, and increasingly easy for doctors and patients to detect the early stages of latent diseases. Researchers at the Institute of Physical Chemistry of the Polish Academy of Sciences in Warsaw and the University of North Texas in Denton have perfected a method of producing thin detecting films that are able to recognize specific proteins.

31 Oct 2015

Rotation model provides explanation of ligand activation mechanism of dimeric receptors

"This 'rotation model', which made the cover of BioEssays, represents a true paradigm shift in the membrane receptor field," stated Prof. Pierre De Meyts, a renowned researcher of insulin and receptor binding for almost half a century and one of the reviewers of the paper by Prof. Ichiro Maruyama, the head of the Information Processing Biology Unit at Okinawa Institute of Science and Technology Graduate University.

31 Oct 2015

Resistance to CD19 CAR T-cell therapy can be caused by CD19 splicing alterations

Resistance to CD19 CAR T-cell therapy, a type of immunotherapy that yields long-lasting remissions in many patients with B-cell leukemia, can be caused by CD19 splicing alterations, leading to loss of certain parts of the CD19 protein that are recognized by the CAR T cells.

31 Oct 2015

Scientists look through evolutionary lens to gain clearer picture of health, disease

To gain a clearer picture of health and disease, scientists have now provided an independent reference for all human variation by looking through the evolutionary lens of our nearest relatives.

31 Oct 2015

UCSD researchers develop new computational strategy to find tumor-shrinking molecules

Patients with glioblastoma, a type of malignant brain tumor, usually survive fewer than 15 months following diagnosis. Since there are no effective treatments for the deadly disease, University of California, San Diego researchers developed a new computational strategy to search for molecules that could be developed into glioblastoma drugs. In mouse models of human glioblastoma, one molecule they found shrank the average tumor size by half.

31 Oct 2015

Coating implants with tissue plasminogen activator can prevent biofilm-related infections

Biofilms--mats of bacteria similar to the plaque that grows on teeth--frequently coat the surfaces of catheters, and of various medical implants and prostheses, where they can threaten lives or lead to failure of the implants. Antibiotics are impotent against biofilms.

31 Oct 2015

Prkci gene maintains balance in stem cell production

When it comes to stem cells, too much of a good thing isn't wonderful: producing too many new stem cells may lead to cancer; producing too few inhibits the repair and maintenance of the body.

31 Oct 2015

Blocking calcium-signaling pathway could inhibit Ebola virus and other sources of deadly infections

The Ebola virus acts fast. The course of infection, from exposure to recovery, or death, can take as little as two weeks. That may not leave enough time for the immune system to mount an effective response.

31 Oct 2015

RNA profiles of tumor-educated platelets may diagnose cancer, identify potential therapeutic approaches

Analysis of tumor RNA carried in platelets - blood components best known for their role in clotting - may prove to be more useful than other "liquid biopsy" technologies for diagnosing cancer and determining its primary location and potential therapeutic approaches.

31 Oct 2015

Researchers discover key regulator that impacts survival of lymphoma patients

An important regulator that controls the ability of tumour cells to hide from the immune system in lymphoma patients, making them unlikely to respond to standard treatment, has been discovered by scientists at the University of Oxford.

31 Oct 2015

Low-fat diets do not lead to greater weight loss in long term, shows meta-analysis research

Low-fat diets do not lead to greater weight loss in the long term compared to higher-fat diets of similar intensity, according to a large meta-analysis involving more than 68000 adults, published in The Lancet Diabetes & Endocrinology journal.

31 Oct 2015

Scientists identify new jelly-like properties of essential proteins that lead to serious diseases

Scientists at the University of Cambridge have identified a new property of essential proteins which, when it malfunctions, can cause the build up, or 'aggregation', of misshaped proteins and lead to serious diseases.

31 Oct 2015

Lack of adequate sleep can interfere with fundamental cellular process

Lack of adequate sleep can do more than just make you tired. It can short-circuit your system and interfere with a fundamental cellular process that drives physical growth, physiological adaptation and even brain activity, according to a new study from the University of Tennessee, Knoxville.

30 Oct 2015

G Protein News and Research

Researchers use genomic techniques to show why different strains of Salmonella infect particular animal species

Small subtype of immune cells appears to prevent obesity

Griffith University uncovers first 3-D image of protein linked to cancer spread

Researchers identify tumor suppressor genes that drive subset of melanomas

Findings provide a step towards personalized cancer therapy

Diet rich in soy protein and isoflavones can protect menopausal women from osteoporosis

Key protein controls stem cell properties that could make them useful in regenerative medicine

Researchers develop more accurate method of imprinting proteins

Rotation model provides explanation of ligand activation mechanism of dimeric receptors

Resistance to CD19 CAR T-cell therapy can be caused by CD19 splicing alterations

Scientists look through evolutionary lens to gain clearer picture of health, disease

UCSD researchers develop new computational strategy to find tumor-shrinking molecules

Coating implants with tissue plasminogen activator can prevent biofilm-related infections

Prkci gene maintains balance in stem cell production

Blocking calcium-signaling pathway could inhibit Ebola virus and other sources of deadly infections

RNA profiles of tumor-educated platelets may diagnose cancer, identify potential therapeutic approaches

Researchers discover key regulator that impacts survival of lymphoma patients

Low-fat diets do not lead to greater weight loss in long term, shows meta-analysis research

Scientists identify new jelly-like properties of essential proteins that lead to serious diseases

Lack of adequate sleep can interfere with fundamental cellular process

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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