Protein C News and Research

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NeoPharm submits IL13-PE38QQR IND for the treatment of IPF

NeoPharm, Inc., announced today that it has filed an investigational new drug application (IND) with the U.S. Food and Drug Administration (FDA) for IL13-PE38QQR (IL13-PE) for the treatment of Idiopathic Pulmonary Fibrosis (IPF). IPF is the most deadly disease of the lungs in humans with very high morbidity. There is currently no proven effective treatment for the cure of this disease.

5 Jan 2010

Scientists uncover an important link between inflammation and breast cancer stem cells

Scientists at the University of Michigan Comprehensive Cancer Center have uncovered an important link between inflammation and breast cancer stem cells that suggests a new way to target cells that are resistant to current treatments.

4 Jan 2010

Discovery of key process in bacterial infection could lead to new drug targets to prevent infection

Bacteria can swim, propelling themselves through fluids using a whip-like extension called a flaggella. They can also walk, strolling along solid surfaces using little fibrous legs called pili. It is this motility that enable some pathogenic bacteria to establish the infections - such as meningitis - that cause their human hosts to get sick or even die.

4 Jan 2010

BiPro completes the requirements of NSF International's Athletic Banned Substances Certification Program

BiProUSA announced today that BiPro, an all natural whey protein isolate (dairy protein), has successfully completed the requirements of NSF International's Athletic Banned Substances Certification Program, Certified for Sport(TM).

4 Jan 2010

Research may point to more effective therapeutic targets for prion diseases

Scientists from The Scripps Research Institute have determined for the first time that prions, bits of infectious protein devoid of DNA or RNA that can cause fatal neurodegenerative disease, are capable of Darwinian evolution.

4 Jan 2010

UI cell membrane protein study may lead to new methods of tracking metastasizing cancer cells

With the discovery of a new type of chemical modification on an important muscle protein, a University of Iowa study improves understanding of certain muscular dystrophies and could potentially lead to new treatments for the conditions.

4 Jan 2010

Bacterial enzyme decreases cocaine desire

A recent study shows that a bacterial protein may help cocaine addicts break the habit.

3 Jan 2010

Cardiologist wins stimulus grant to identify biomarkers of idiopathic pulmonary hypertension

Johns Hopkins Children's Center cardiologist Allen Everett recently won more than $460,000 in stimulus grant funding to identify the biomarkers of idiopathic pulmonary hypertension (IPH), a progressive and highly lethal condition in children and adults marked by persistently elevated pressure in the artery that carries blood from the heart to the lungs.

31 Dec 2009

Multivariable analyses identify epidemiological risk factors for ovarian cancer

Concentrations of the biomarkers CA125, human epididymis protein 4 (HE4), and mesothelin began to rise 3 years before clinical diagnosis of ovarian cancer, according to a new study published online December 30 in the Journal of the National Cancer Institute. However, the biomarkers became substantially elevated only in the last year prior to diagnosis.

31 Dec 2009

Final results of Maxygen's modified "Dutch Auction" tender offer announced

Maxygen, Inc., a biopharmaceutical company focused on the development of improved versions of protein drugs, today announced the final results of its modified "Dutch Auction" tender offer, which expired at 5:00 p.m., New York City time, on December 23, 2009.

31 Dec 2009

Pfizer provides update on Prevnar 13

Pfizer Inc. announced today that the U.S. Food and Drug Administration (FDA) has not yet completed its review of the Biologics License Application (BLA) for Prevnar 13™, (Pneumococcal 13-valent Conjugate Vaccine [Diphtheria CRM197 Protein]), the Company’s candidate 13-valent pneumococcal conjugate vaccine.

31 Dec 2009

Dr. Ken Hopper of LifeSynch offers simple tips toward achieving New Year's weight loss resolution

It's that time of year. Gyms will be flooded with people ready to step on a treadmill. Grocery carts will be filled with fruits and vegetables instead of frozen pizza and chips. People will enter the New Year resolved to lose weight. But surveys show that most people don't keep this resolution.

31 Dec 2009

Tarantula venom protein promising for MD

University at Buffalo biophysicists have found a protein in tarantula venom that shows promise as a potential therapy for muscular dystrophy (MD). They have formed a start-up biotech company in Buffalo -- Rose Pharmaceuticals -- to advance the drug to clinical trials.

30 Dec 2009

Majority of Americans fail at keeping their New Years resolutions to lose weight and get in shape

Nutritionist Judy Pentra, of Patients Medical, a multi-specialty wellness center in New York, warns that the New Year can be a vulnerable time for people trying to lose weight and get in shape. The average person can gain 2-5 pounds during the holidays and many resolve to lose the weight in January, however, 70 percent of Americans fail at keeping their New Years resolutions.

30 Dec 2009

ADA recommends the A1C test for diabetes screening and diagnosis

New official guidelines for diabetes screening and diagnosis now include a blood test that gives a person's average blood glucose level over the previous 2-3 months.

30 Dec 2009

Advances in development of “lipidoid” formulations for systemic delivery of RNAi therapeutics

Alnylam Pharmaceuticals, Inc., a leading RNAi therapeutics company, and collaborators from the David H. Koch Institute for Integrative Research at the Massachusetts Institute of Technology (MIT) today announced the publication of new data in the journal Proceedings of the National Academy of Sciences (PNAS) describing further advancements in discovery and development of novel “lipidoid” formulations for the systemic delivery of RNAi therapeutics.

30 Dec 2009

TRAP-1 may prevent cancer cell death, current research suggests

Current research suggests that TNF-receptor associated protein-1 (TRAP-1) may prevent cancer cell death. The related report by Leav et al, "Cytoprotective Mitochondrial Chaperone TRAP-1 as a Novel Molecular Target in Localized and Metastatic Prostate Cancer," appears in the January 2010 issue of the American Journal of Pathology.

30 Dec 2009

CSL Behring awards four advocacy grants to patient organizations in the U.S.

CSL Behring, a global leader in the plasma-protein biotherapies industry and a subsidiary of CSL Limited, has awarded four advocacy grants totaling $87,000 to patient organizations in the United States through the Local Empowerment for Advocacy Development (LEAD) program.

29 Dec 2009

Results from Bionovo's study on BN107 published

Bionovo, Inc. announced today the publication of results from its study on the anti-tumor mechanism of BN107. The results of the study, published in the International Journal of Cancer, describe the potential molecular mechanisms mediating the selective pro-apoptotic (cell death) effect induced by BN107 on estrogen receptor negative (ER-) breast cancer cells.

29 Dec 2009

Food Safety News lists its top ten ten food safety stories of 2009

Food Safety News, the web-based newspaper that covers all things food safety, today published its list of the top ten food safety stories of the year.

29 Dec 2009

Protein C News and Research

NeoPharm submits IL13-PE38QQR IND for the treatment of IPF

Scientists uncover an important link between inflammation and breast cancer stem cells

Discovery of key process in bacterial infection could lead to new drug targets to prevent infection

BiPro completes the requirements of NSF International's Athletic Banned Substances Certification Program

Research may point to more effective therapeutic targets for prion diseases

UI cell membrane protein study may lead to new methods of tracking metastasizing cancer cells

Bacterial enzyme decreases cocaine desire

Cardiologist wins stimulus grant to identify biomarkers of idiopathic pulmonary hypertension

Multivariable analyses identify epidemiological risk factors for ovarian cancer

Final results of Maxygen's modified "Dutch Auction" tender offer announced

Pfizer provides update on Prevnar 13

Dr. Ken Hopper of LifeSynch offers simple tips toward achieving New Year's weight loss resolution

Tarantula venom protein promising for MD

Majority of Americans fail at keeping their New Years resolutions to lose weight and get in shape

ADA recommends the A1C test for diabetes screening and diagnosis

Advances in development of “lipidoid” formulations for systemic delivery of RNAi therapeutics

TRAP-1 may prevent cancer cell death, current research suggests

CSL Behring awards four advocacy grants to patient organizations in the U.S.

Results from Bionovo's study on BN107 published

Food Safety News lists its top ten ten food safety stories of 2009

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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