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New chemical compound shows promise in restoring function lost to spinal cord injury

Case Western Reserve scientists have developed a new chemical compound that shows extraordinary promise in restoring function lost to spinal cord injury. The compound, which the researchers dubbed intracellular sigma peptide (ISP), allowed paralyzed muscles to activate in more than 80 percent of the animals tested.

4 Dec 2014

Researchers identify biochemical mechanism that could lead to 'chemo brain'

UNC School of Medicine researchers have found for the first time a biochemical mechanism that could be a cause of "chemo brain" - the neurological side effects such as memory loss, confusion, difficulty thinking, and trouble concentrating that many cancer patients experience while on chemotherapy to treat tumors in other parts of the body.

4 Dec 2014

Scientists review HBV-associated tumor microenvironment in hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is one of the few cancers in which a continued increase in incidence has been observed over recent years. Globally, there are approximately 750,000 new cases of liver cancer reported each year. Importantly, population-based studies show that HCC ranks as the third leading cause of cancer-related deaths worldwide.

4 Dec 2014

Protein that regulates the body's sleep cycle may offer cancer protection

People who work around the clock could actually be setting themselves back, according to Virginia Tech biologists.

4 Dec 2014

Cytation™ 5 Cell Imaging Multi-Mode Reader to be introduced by BioTek at ASCB 2014

Join BioTek Instruments as they introduce the Cytation™ 5 Cell Imaging Multi-Mode Reader at the ASCB 2014 Conference and Exhibition to be held December 6-10 in Philadelphia, Pennsylvania. BioTek’s “Think Possible” philosophy is reflected in their microplate-based imaging, detection, liquid handling and automation solutions and the company will showcase their newest innovations at Booth #349.

3 Dec 2014

Human stem cells made from adult donor cells remember their origin, say McMaster scientists

Scientists at McMaster University have discovered that human stem cells made from adult donor cells "remember" where they came from and that's what they prefer to become again.

3 Dec 2014

Scientists develop system for printing protein patterns onto film

Protein-coated Petri dishes are increasingly being used to support cell growth during cell cultivation. Scientists have developed a system for printing protein patterns onto film using a roll-to-roll process, which allows high volumes to be manufactured efficiently and cost-effectively.

3 Dec 2014

SAFit-ligands provide foundation for novel treatment of stress-related psychiatric disorders

The FK506-binding protein 51 (FKBP51) is an established risk factor for stress-related psychiatric disorders such as major depression. Drug discovery for FKBP51 has been hampered by the inability to pharmacologically differentiate against the very similar functional counterplayer FKBP52.

3 Dec 2014

Researchers remake brain and gut stem cells to study potential therapies for fatal diseases

Research scientists have developed a novel method to re-create brain and intestinal stem cells from patients who died decades ago, using DNA from stored blood samples to study the potential causes of debilitating illnesses such as inflammatory bowel disease.

3 Dec 2014

Abnormal activation of cell death pathways may lead to inflammatory skin diseases

Inflammatory skin diseases such as psoriasis may result from abnormal activation of cell death pathways previously believed to suppress inflammation, a surprise finding that could help to develop new ways of treating these diseases.

3 Dec 2014

Scientists reveal how bacterial nanodrills enter into our cells to kill them

A team of scientists has revealed how certain harmful bacteria drill into our cells to kill them. Their study shows how bacterial 'nanodrills' assemble themselves on the outer surfaces of our cells, and includes the first movie of how they then punch holes in the cells' outer membranes.

3 Dec 2014

Researchers find way to prevent noise-induced hearing loss

Researchers from Weill Cornell Medical College and the Gladstone Institutes have found a way to prevent noise-induced hearing loss in a mouse using a simple chemical compound that is a precursor to vitamin B3. This discovery has important implications not only for preventing hearing loss, but also potentially for treating some aging-related conditions that are linked to the same protein.

3 Dec 2014

Researchers create synthetic surface to control adhesion of E. coli bacteria

A research team from Kiel University and Goethe University Frankfurt has jointly created a synthetic surface on which the adhesion of E. coli bacteria can be controlled. The layer, which is only approximately four nanometres thick, imitates the saccharide coating (glycocalyx) of cells onto which the bacteria adhere such as during an infection. This docking process can be switched on and off using light.

3 Dec 2014

BWH researchers identify cells responsible for fibrosis

Researchers from Brigham and Women's Hospital have identified what they believe to be the cells responsible for fibrosis, the buildup of scar tissue. Fibrotic diseases, such as chronic kidney disease and failure, lung disease, heart failure and cirrhosis of the liver, are estimated to be responsible for up to 45 percent of deaths in the developed world.

2 Dec 2014

Monash University, 60P Australia partner to develop Fenretinide drug for dengue fever

Monash University and 60P Australia Pty Ltd, a subsidiary of 60° Pharmaceuticals LLC, have announced today an exclusive partnering deal, with 60P obtaining rights to develop the drug Fenretinide for dengue fever.

2 Dec 2014

InnaVirVax receives DSMB recommendation to pursue VAC-3S Phase 2 study in HIV

InnaVirVax, a biopharmaceutical company specialized in research and development on therapeutic and diagnostic solutions for diseases linked to immune dysregulation, today announces the recommendation of its independent Data Safety and Monitoring Board (DSMB) to pursue the Phase 2 study (IPROTECT1) of VAC-3S according to the planned protocol.

2 Dec 2014

Faster and more accurate method for testing new cancer drugs

Finding faster and more accurate ways to test new cancer drugs is always a priority for cancer researchers.

2 Dec 2014

New cellPACK software can help explore human cells in more detail

Researchers can now explore viruses, bacteria and components of the human body in more detail than ever before with software developed at The Scripps Research Institute.

2 Dec 2014

Global stem cell market estimated to reach US$117.66B in 2018

Stem cells have the potential to transform healthcare by enabling the cost-effective treatment of many conditions that currently have poor treatment options.

2 Dec 2014

Study paves way for further research on brain evolution

The neocortex is the part of the brain that enables us to speak, dream, or think. The underlying mechanism that led to the expansion of this brain region during evolution, however, is not yet understood. A research team headed by Wieland Huttner, director at the Max Planck Institute of Molecular Cell Biology and Genetics, now reports an important finding that paves the way for further research on brain evolution: The researchers analyzed the gyrencephaly index, indicating the degree of cortical folding, of 100 mammalian brains and identified a threshold value that separates mammalian species into two distinct groups: Those above the threshold have highly folded brains, whereas those below it have only slightly folded or unfolded brains.

2 Dec 2014

B Cell News and Research

New chemical compound shows promise in restoring function lost to spinal cord injury

Researchers identify biochemical mechanism that could lead to 'chemo brain'

Scientists review HBV-associated tumor microenvironment in hepatocellular carcinoma

Protein that regulates the body's sleep cycle may offer cancer protection

Cytation™ 5 Cell Imaging Multi-Mode Reader to be introduced by BioTek at ASCB 2014

Human stem cells made from adult donor cells remember their origin, say McMaster scientists

Scientists develop system for printing protein patterns onto film

SAFit-ligands provide foundation for novel treatment of stress-related psychiatric disorders

Researchers remake brain and gut stem cells to study potential therapies for fatal diseases

Abnormal activation of cell death pathways may lead to inflammatory skin diseases

Scientists reveal how bacterial nanodrills enter into our cells to kill them

Researchers find way to prevent noise-induced hearing loss

Researchers create synthetic surface to control adhesion of E. coli bacteria

BWH researchers identify cells responsible for fibrosis

Monash University, 60P Australia partner to develop Fenretinide drug for dengue fever

InnaVirVax receives DSMB recommendation to pursue VAC-3S Phase 2 study in HIV

Faster and more accurate method for testing new cancer drugs

New cellPACK software can help explore human cells in more detail

Global stem cell market estimated to reach US$117.66B in 2018

Study paves way for further research on brain evolution

Using single B cell screening to boost antibody discovery eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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