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Scientists detect several biomarkers to screen active drugs for Batten disease

Goethe University and Harvard Medical School start screening for active ingredients for the treatment of Batten disease

20 Apr 2011

Combination therapy restores skilled use of limb in rodent model

After the acute treatment window closes, the only effective treatment for stroke is physical/occupational therapy. Now scientists from Children's Hospital Boston report a two-pronged molecular therapy that leads to significant recovery of skilled motor function in a rat model of stroke.

20 Apr 2011

Dental diagnosis and treatment for snoring and sleep apnoea

Over seven million people in Spain are at risk of developing sleep apnoea (SA), a health problem caused by obstructed air intake during sleep.

20 Apr 2011

MSF calls on African governments, WHO to switch to newer, more expensive treatment for severe malaria

Nearly 200,000 deaths from severe malaria could be averted if African governments replaced the low-cost antimalarial quinine with the more expensive but more effective drug artesunate, according to a report (.pdf) released Tuesday by Medicins Sans Frontieres (MSF), Reuters reports (Kelland, 4/19).

20 Apr 2011

OSU biophysicist leverages computer cluster to develop drug to block small protein molecule IL-6

An Ohio State biophysicist used a supercomputer to search thousands of molecular combinations for the best configuration to block a protein that can cause breast or prostate cancer.

20 Apr 2011

Cord blood units treated with signaling molecule show favorable safety profile in long-term animal studies

An innovative experimental treatment for boosting the effectiveness of stem-cell transplants with umbilical cord blood has a favorable safety profile in long-term animal studies, report scientists from Dana-Farber Cancer Institute, Beth Israel Deaconess Medical Center, and Children's Hospital Boston.

20 Apr 2011

Ohio State biophysicist disrupts cellular messages through fragment-based drug design

An Ohio State biophysicist used a supercomputer to search thousands of molecular combinations for the best configuration to block a protein that can cause breast or prostate cancer.

19 Apr 2011

Parents open to genetic tests for children

Genetic testing techniques have not been perfected yet but parents are willing to take the risk to know if their children are at risk for diseases in adulthood. Some parents would like the ability to predict the future, in terms of their child's risk for certain chronic health conditions. This comes in a new study published online in the journal Pediatrics. Experts, however, say the tests are of little value at this time.

19 Apr 2011

New neoprene inhaler cover for children with asthma

InhalerWear announces a new neoprene cover for inhalers that will help make carrying around an inhaler trendy and cool to children and teenagers. The new inhaler cover is affordable, stylish and can simply be clipped to a backpack, sports bag or keychain like an accessory.

19 Apr 2011

SafeMinds calls for immediate vaccine safety studies in autistic children

Alison MacNeil issued the following statements today regarding vaccines.

19 Apr 2011

New research confirms cigarettes' toxic impact on environment

Each year more than 360 billion cigarettes are smoked in the United States. Where do all those butts go? Public roads, waterways, parks and beaches. New research released today further demonstrates the negative impact that cigarette filters and discarded cigarette butts have on the environment.

19 Apr 2011

Overweight and obese parents more likely to view school-time activity as inadequate

Childhood obesity affects 1 of every 6 kids in the United States, in part due to a lack of physical activity. Schools can play a key part in offering elementary-age kids lots of chances to be active—on the playground during recess and when they're in gym.

19 Apr 2011

Young scoliosis patients do not need routine MRI scanning before spinal surgery

Most patients with scoliosis developing after age ten don't need routine magnetic resonance imaging scanning before spine-straightening surgery, suggests a study in the April 14 issue of Spine. The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health.

19 Apr 2011

Pulitzer Prize-winning photojournalist takes new challenge to combat cancer

Pulitzer Prize-winning photojournalist John Kaplan has taken on a new challenge: to give away 10,000 DVD copies of his new nationally acclaimed autobiographical film, Not As I Pictured to anyone affected by cancer.

19 Apr 2011

Exacerbate-reverse' approach can identify potential therapy for fatal childhood disease

Many genes that cause human diseases have parallel genes in other organisms, including yeast. Now Columbia University researchers have used an innovative yeast-based screening method to identify a possible treatment for the fatal childhood disease Niemann-Pick C.

19 Apr 2011

Mother's diet during pregnancy can influence child's risk of obesity

Scientists have discovered that a mother's nutrition during pregnancy can strongly influence her child's risk of obesity many years later.

19 Apr 2011

G20 finance ministers' meeting concludes

G20 finance ministers "concluded three days of talks late Saturday with pledges of greater cooperation to avert another financial crisis, leaving uncertain how far they would go in changing their domestic policies in response to international pressures," the Associated Press/Christian Science Monitor reports.

19 Apr 2011

IU, Ohio and Kentucky partner to advance childhood disease research

Children's doctors in Indiana soon will partner with colleagues in Ohio and Kentucky through a new program focused on working across state lines to advance research on childhood disease.

19 Apr 2011

New biomarker-based test more effective for early acute kidney injury detection

A new biomarker-based diagnostic test is more effective than the current best practice for early detection of adverse outcomes after acute kidney injury, which can be fatal for an estimated 50 percent of the critically ill patients who get the condition.

19 Apr 2011

New study finds treatment-resistant epilepsy common in idiopathic autism

A new study found that treatment-resistant epilepsy (TRE) is common in idiopathic autism. Early age at the onset of seizures and delayed global development were associated with a higher frequency of resistance to antiepileptic drugs (AEDs). Full findings appear online in Epilepsia, a journal published by Wiley-Blackwell on behalf of the International League Against Epilepsy (ILAE).

19 Apr 2011