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Study summarizes new evidence on using probiotics for specific health conditions

Probiotic supplements are widely available and are sometimes promoted as a general way to support gut microbiome and promote health.

1 Jun 2020

Preventing novel coronavirus from entering into a host cell

How might the novel coronavirus be prevented from entering a host cell in an effort to thwart infection? A team of biomedical scientists has made a discovery that points to a solution.

30 May 2020

New genetic engineering technique sets the stage for advances in medicine and beyond

From bacteria-made insulin that obviates the use of animal pancreases to a better understanding of infectious diseases and improved treatments, genetic engineering of bacteria has redefined modern medicine. Yet, serious limitations remain that hamper| progress in numerous other areas.

30 May 2020

Changes in gut mucus are linked to brain disorders

Mucus is the first line of defense against bad bacteria in our gut. But could it also be part of our defense against diseases of the brain?

29 May 2020

Study: Glucocorticoids are harmful for patients suffering from viral respiratory infections

Glucocorticoids are widely used in treating acute respiratory distress syndrome (ARDS) despite there being no indisputable scientific evidence of their effectiveness.

29 May 2020

Rare deadly disease linked to coronavirus infection seen in children

Now, new evidence has shown that children with coronavirus disease (COVID-19) experience a Kawasaki-like illness, called multisystem inflammatory syndrome in children (MIS-C). The complication is akin to toxic shock syndrome, a condition that occurs due to sepsis. Though rare, the condition is life-threatening.

29 May 2020

5-day Remdesivir dose works as well as the 10-day dose in COVID-19, study finds

With more than 5.8 million people infected with the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the search is on for an effective SARS-CoV-2 vaccine or drug to treat COVID-19 disease.

28 May 2020

Ferritin heavy chain protein shows promise as a potential SARS-CoV-2 vaccine or antiviral

A new study published on the online preprint server bioRxiv in May 2020 reports the construction and testing of a new ferritin-based antigen-bearing protein that has biological activity towards the ACE2 receptor. This could indicate its potential for development as a vaccine or antiviral.

28 May 2020

New drug combinations could help overcome genetic immunotherapy resistance

A new study from researchers at the UCLA Jonsson Comprehensive Cancer Center helps explain how disruptions in genes can lead to the resistance to one of the leading immunotherapies, PD-1 blockade, and how new drug combinations could help overcome resistance to the anti-PD-1 therapy in a mechanistically-based way.

28 May 2020

Novel antiviral, antibacterial surface can reduce hospital-acquired infections

The novel coronavirus pandemic has caused an increased demand for antimicrobial treatments that can keep surfaces clean, particularly in health care settings.

27 May 2020

Disordered gut microbiomes are found in patients with hemorrhagic brain disease

A new study shows that people with a rare genetic disease that causes bleeding in the brain have gut microbiomes distinct from those without the disease.

27 May 2020

New strategy identified to address the underlying cause of LAD1 patients' symptoms

Owing to a rare genetic mutation, individuals with leukocyte adhesion deficiency type 1 (LAD1) experience a suite of symptoms that trace back to an immune system dysfunction.

27 May 2020

Novel testing system predicts outcomes in patients with sepsis

More than 1.7 million Americans develop sepsis each year, and more than 270,000 die from it. The condition--which happens when the body has an extreme response to a bacterial or viral infection, causing a chain reaction that can lead to organ failure and death--has few strategies for treatment.

26 May 2020

Preterm birth rates during COVID-19 in Denmark

The current COVID-19 outbreak was declared a pandemic in March 2020 by the World Health Organization (WHO). This led to the enforcement of a lockdown on an almost global scale with wide-ranging consequences. Now, a new Danish study published on the preprint server medRxiv* in May 2020 reveals the impact on preterm birth rates.

26 May 2020

Rats on the rampage as leftovers from closed restaurants become scarce, warns CDC

The Centre for Disease Prevention and Control (CDC) has warned that as restaurants are closed due to social distancing and lockdowns owing to the COVID-19 pandemic, rats are resurfacing en masse. The CDC warns that these rats are becoming aggressive as they are deprived of their usual source of food.

25 May 2020

Teens develop septic shock due to COVID-19

Since the emergence of the novel coronavirus disease (COVID-19), most people who develop severe illness are older adults, those with underlying medical conditions, and those who are immunocompromised. Though children are mostly spared, some adolescents developed septic shock due to COVID-19, a new study has found.

24 May 2020

Smokers at increased risk of severe COVID-19 according to a large population study

A new UK study available on the preprint server medRxiv screened 2.4 million users of a symptom reporting application during the coronavirus disease (COVID-19) pandemic, revealing that smokers are at higher risk of increased symptom burden and more prone to hospitalization.

24 May 2020

Understanding mechanism behind antibiotic-resistant gonorrhea sets stage for new treatments

Due to the spread of antibiotic-resistant strains of Neisseria gonorrhoeae, existing treatments for gonorrhea, the sexually transmitted infection caused by the bacterium, are no longer effective. In the absence of a vaccine, there is an urgent need to develop novel treatment options.

22 May 2020

New clinical trial to test treatment that targets overactive immune response to COVID-19

For some COVID-19 patients, the body's immune response may be as destructive as the virus that causes the disease.

22 May 2020

IL-6 blocker use in severe COVID-19 increases risk of secondary infections

With many hundreds of thousands of deaths due to the current COVID-19 pandemic, there is a rush to find an effective vaccine or drug against the virus. A new study on the preprint server medRxiv* in May 2020 shows that the use of some biologically plausible drugs may be counterproductive, and care should be taken when trying out unproven therapies.

22 May 2020

Bacterial News and Research

Study summarizes new evidence on using probiotics for specific health conditions

Preventing novel coronavirus from entering into a host cell

New genetic engineering technique sets the stage for advances in medicine and beyond

Changes in gut mucus are linked to brain disorders

Study: Glucocorticoids are harmful for patients suffering from viral respiratory infections

Rare deadly disease linked to coronavirus infection seen in children

5-day Remdesivir dose works as well as the 10-day dose in COVID-19, study finds

Ferritin heavy chain protein shows promise as a potential SARS-CoV-2 vaccine or antiviral

New drug combinations could help overcome genetic immunotherapy resistance

Novel antiviral, antibacterial surface can reduce hospital-acquired infections

Disordered gut microbiomes are found in patients with hemorrhagic brain disease

New strategy identified to address the underlying cause of LAD1 patients' symptoms

Novel testing system predicts outcomes in patients with sepsis

Preterm birth rates during COVID-19 in Denmark

Rats on the rampage as leftovers from closed restaurants become scarce, warns CDC

Teens develop septic shock due to COVID-19

Smokers at increased risk of severe COVID-19 according to a large population study

Understanding mechanism behind antibiotic-resistant gonorrhea sets stage for new treatments

New clinical trial to test treatment that targets overactive immune response to COVID-19

IL-6 blocker use in severe COVID-19 increases risk of secondary infections

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