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Diet missing soluble fiber promotes inflammation in the intestines, leading to weight gain

Eating too much high-fat, high-calorie food is considered the primary cause of obesity and obesity-related disease, including diabetes. While the excess calories consumed are a direct cause of the fat accumulation, scientists suspect that low-grade inflammation due to an altered gut microbiome may also be involved.

30 Oct 2015

Specialized type of immunotherapy can boost survival from pancreatic cancer

A new study in mice by researchers at Fred Hutchinson Cancer Research Center has found that a specialized type of immunotherapy — even when used without chemotherapy or radiation — can boost survival from pancreatic cancer, a nearly almost-lethal disease, by more than 75 percent. The findings are so promising, human clinical trials are planned within the next year.

30 Oct 2015

Findings could lead to new treatment for ALS, dementia

University of Toronto (U of T) researchers are proposing a new way of understanding Amyotrophic Lateral Sclerosis (ALS), the devastating and incurable neurological disease. Their findings, published today in the journal Neuron, could be a major milestone on the path to a treatment for both ALS and dementia.

30 Oct 2015

Single gene variation may influence obesity in children, adults

A single variation in the gene for brain-derived neurotropic factor (BDNF) may influence obesity in children and adults, according to a new study funded by the National Institutes of Health.

30 Oct 2015

Study reveals mechanism behind protein-related diseases

Dartmouth researchers have found that some proteins turn into liquid droplets on the way to becoming toxic solids implicated in neurodegenerative diseases and other genetic disorders.

30 Oct 2015

Researchers identify molecular switch that can convert unhealthy white fat into energy-burning brown fat

A research team led by UC San Francisco scientists has identified a molecular switch capable of converting unhealthy white fat into healthy, energy-burning brown fat in mice. Drugs that flip this switch rapidly reduced obesity and diabetes risk factors in mice fed a high fat diet.

30 Oct 2015

Scientists one step closer to developing new treatment for inflammatory bowel disease

For patients with inflammatory bowel disease, the possibility of taking a single pill to bring long-lasting relief might seem too good to be true. Scientists at the Lewis Katz School of Medicine at Temple University are on the brink of making that happen, thanks to a recent proof-of-concept study, in which the severity of a form of inflammatory bowel disease in mice was dramatically reduced with one oral dose of a protein isolated from a bacterial biofilm.

30 Oct 2015

President and CEO of Protein Sciences elected as 2015 Fellow of the International Society for Vaccines

Protein Sciences Corporation, the makers of Flublok Influenza Vaccine, announced today that Dr. Manon Cox, President and CEO, was elected as a 2015 Fellow of the International Society for Vaccines (ISV). The ISV is an esteemed organization dedicated to the development, advancement and use of vaccines to prevent and control disease.

30 Oct 2015

Adelaide researchers identify key protein involved in 'super-inflammatory' immune response

Researchers have made another important step in the progress towards being able to block the development of multiple sclerosis (MS) and other autoimmune diseases.

29 Oct 2015

New research shows that autophagy can operate in cell nucleus to guard against start of cancer

Autophagy, literally self-eating or the degradation of unwanted cellular bits and pieces by the cell itself, has been shown for the first time to also work in the cell nucleus. In addition, in this setting it plays a role in guarding against the start of cancer, according to new research from the Perelman School of Medicine at the University of Pennsylvania.

29 Oct 2015

Rutgers Cancer Institute scientist leads phase III trial of FDA-approved viral melanoma therapy

The U.S. Food and Drug Administration has approved a viral melanoma therapy that was the focus of a phase III clinical trial led by Rutgers Cancer Institute of New Jersey Associate Director for Clinical Science and Chief Surgical Officer Howard L. Kaufman, MD, FACS.

29 Oct 2015

Dementia specialists, PET imaging providers can now register to participate in IDEAS Study

Dementia specialists and PET imaging providers can now register to participate in the Imaging Dementia - Evidence for Amyloid Scanning (IDEAS) Study at Ideas-Study.org.

29 Oct 2015

GDF10 molecule identified as a key player in repair mechanisms after stroke

Looking at brain tissue from mice, monkeys and humans, scientists have found that a molecule known as growth and differentiation factor 10 (GDF10) is a key player in repair mechanisms following stroke. The findings suggest that GDF10 may be a potential therapy for recovery after stroke.

29 Oct 2015

Upstream Medical Technologies formed to revolutionise accurate diagnosis of heart conditions

A new company that could revolutionise the accurate diagnosis of heart conditions was launched in Christchurch, New Zealand today.

29 Oct 2015

Researchers report new way to help improve vaccines using molecules that direct the immune system

As the days get colder and shorter, we carve jack-o-lanterns and drink pumpkin spice lattes. But one fall tradition can actually keep you healthy: getting your flu shot. Like all vaccines, the flu shot trains the immune system to fend off infection, but some need help to produce the full effect.

29 Oct 2015

New broad-spectrum antibiotic can kill bacteria by punching holes in their membranes

Bacteria have many methods of adapting to resist antibiotics, but a new class of spiral polypeptides developed at the University of Illinois targets one thing no bacterium can live without: an outer membrane.

29 Oct 2015

Liposomal sizing and the Coulter principle: an interview with Professor Melvin E. Klegerman

For about the last 25 years, the cardiology group here have been developing a platform technology for both the diagnosis and treatment of atherosclerosis.

From Beckman Coulter Life Sciences - Particle Counting and Characterization 28 Oct 2015

Researchers identify inherited gene variation associated with pediatric acute lymphoblastic leukemia

Researchers studying two generations of a family affected by pediatric acute lymphoblastic leukemia (ALL) have identified an inherited variation in the ETV6 gene that is associated with an increased risk of developing the disease. St. Jude Children's Research Hospital investigators led the study, which appears in the October 28 issue of the journal Lancet Oncology.

28 Oct 2015

Expectant mothers encouraged to eat balanced diet to reduce obesity risk in unborn child

Overweight and obese women who gain excessive weight during pregnancy may be putting their babies at risk of a lifetime of obesity.

28 Oct 2015

Researchers identify role of cGAS enzyme in autoimmune diseases

Activating an enzyme that sounds an alarm for the body's innate immune system causes two lethal autoimmune diseases in mice, while inhibiting the same enzyme rescues them, UT Southwestern Medical Center researchers report.

28 Oct 2015

G Protein News and Research

Diet missing soluble fiber promotes inflammation in the intestines, leading to weight gain

Specialized type of immunotherapy can boost survival from pancreatic cancer

Findings could lead to new treatment for ALS, dementia

Single gene variation may influence obesity in children, adults

Study reveals mechanism behind protein-related diseases

Researchers identify molecular switch that can convert unhealthy white fat into energy-burning brown fat

Scientists one step closer to developing new treatment for inflammatory bowel disease

President and CEO of Protein Sciences elected as 2015 Fellow of the International Society for Vaccines

Adelaide researchers identify key protein involved in 'super-inflammatory' immune response

New research shows that autophagy can operate in cell nucleus to guard against start of cancer

Rutgers Cancer Institute scientist leads phase III trial of FDA-approved viral melanoma therapy

Dementia specialists, PET imaging providers can now register to participate in IDEAS Study

GDF10 molecule identified as a key player in repair mechanisms after stroke

Upstream Medical Technologies formed to revolutionise accurate diagnosis of heart conditions

Researchers report new way to help improve vaccines using molecules that direct the immune system

New broad-spectrum antibiotic can kill bacteria by punching holes in their membranes

Liposomal sizing and the Coulter principle: an interview with Professor Melvin E. Klegerman

Researchers identify inherited gene variation associated with pediatric acute lymphoblastic leukemia

Expectant mothers encouraged to eat balanced diet to reduce obesity risk in unborn child

Researchers identify role of cGAS enzyme in autoimmune diseases

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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