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"TimeMachine" algorithm revolutionizes circadian rhythm analysis with single blood sample

"TimeMachine," an algorithm developed by U.S. researchers, accurately predicts circadian phase from a single blood sample using gene expression, offering a novel, efficient approach to understanding circadian rhythms and their impact on health.

9 Jan 2024

New model predicts individual myeloma risk and treatment response

A multicenter collaboration led by researchers at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine has produced the first computational model for newly diagnosed multiple myeloma that predicts an individual's personalized prognosis based on their tumor genomics and treatments.

9 Jan 2024

BCG vaccine's impact on innate immunity explained at cellular level

Bacillus Calmette-Guérin (BCG) is one of the world’s oldest and most widely used vaccines. It was developed in the early 20th century to provide protection from tuberculosis.

9 Jan 2024

American Heart Association Merit Award fuels three research avenues to tackle heart disease

A physician-scientist from Massachusetts researching whether chemicals naturally occurring in foods could help treat heart disease, a genetics expert from Pennsylvania exploring the molecular mechanisms of lipid metabolism and cardiovascular diseases and a California-based professor of cardiovascular medicine studying how vaping impacts the development of abdominal aortic aneurysms are the most recent American Heart Association Merit Award recipients.

9 Jan 2024

CRISPR cures on the horizon: Breakthrough center aims to heal rare, deadly genetic diseases

Children and adults with rare, deadly genetic diseases have fresh hope for curative therapies, thanks to a new collaboration between the Innovative Genomics Institute (IGI) and Danaher Corporation, a global life sciences and diagnostics innovator.

9 Jan 2024

Hidden identity of blood cancer revealed

Leukemia is a common term used to refer to a form of blood cancer. However, there are different types of leukemia depending on the cell type involved.

9 Jan 2024

Infammasomes provide a therapeutic target against human diseases

The structure of inflammasomes and their role in diseases.

9 Jan 2024

Research potentially expands options for patients with aggressive childhood cancer

Research is shedding light and potentially expanding options for patients living with Medulloblastoma, an aggressive childhood cancer.

8 Jan 2024

Study reveals bidirectional association between autoimmune disease and perinatal depression

Women with autoimmune disease are more likely to suffer from depression during pregnancy and after childbirth; conversely, women with a history of perinatal depression are at higher risk of developing autoimmune disease, a new study from Karolinska Institutet published in the journal Molecular Psychiatry reports.

8 Jan 2024

3D mini-organs from human fetal brain tissue unlock new frontier in brain research

Scientists have developed 3D mini-organs from human fetal brain tissue that self-organize in vitro. These lab-grown organoids open up a brand-new way of studying how the brain develops.

8 Jan 2024

New peptide library paves the way for targeting elusive cancer factor MYC

Researchers developed a second-generation NTB bicyclic peptide library, identifying NT-B2R, a peptide that effectively targets MYC, a key factor in most human cancers, demonstrating its potential in inhibiting MYC transcription activities and cancer cell proliferation.

8 Jan 2024

Three cytokine pairs found to be responsible for the body's damaging response to sepsis

Sepsis - when an infection causes the immune system to improperly target the body - is one of the leading causes of death in the ICU.

8 Jan 2024

Engineered virus-like particles power up gene editing, correcting blindness in mice

Prime editing, a versatile form of gene editing that can correct most known disease-causing genetic mutations, now has a new vehicle to deliver its machinery into cells in living animals.

8 Jan 2024

Comprehensive insights on pathophysiology and clinical management of atrial fibrillation

Atrial fibrillation (AF) is a major global health concern impacting millions and causing symptoms like palpitations, dyspnea, fatigue, dizziness, and chest discomfort.

8 Jan 2024

AI reveals hidden rules of cell neighborhoods in cancer

Researchers from Children's Hospital of Philadelphia have developed a new AI-powered algorithm to help understand how different cells organize themselves into particular tissues and communicate with one another.

8 Jan 2024

Gut microbiota: the new frontier in Alzheimer’s disease research and therapy

The current evidence of the role of gut microbiota in Alzheimer’s disease (AD) pathogenesis.

8 Jan 2024

Genetic keys to COVID-19 vaccine response unlocked

A genome-wide association study in the U.K. Biobank reveals genetic factors influencing IgG serostatus against SARS-CoV-2, highlighting the role of HLA class II genes in variable immune responses to COVID-19 vaccines.

7 Jan 2024

Gut enzyme discovery sheds light on bilirubin balance in humans

Researchers study identified BilR, a gut microbiota-derived enzyme, crucial for converting bilirubin to urobilinogen, impacting bilirubin homeostasis in humans.

7 Jan 2024

Fruit fly research solves human disease and fuels new cancer immunotherapy approach

Scientists have solved a cellular murder mystery nearly 25 years after the case went cold. Following a trail of evidence from fruit flies to mice to humans revealed that cannibalistic cells likely cause a rare human immunodeficiency.

5 Jan 2024

Discovery on housekeeping genetic elements reveals a novel avenue in cancer therapy

Technological advancements have enabled scientists to comprehensively explore genetic control elements, unraveling the complexities of gene activation mechanisms in our genetic code.

5 Jan 2024

Genes News and Research

"TimeMachine" algorithm revolutionizes circadian rhythm analysis with single blood sample

New model predicts individual myeloma risk and treatment response

BCG vaccine's impact on innate immunity explained at cellular level

American Heart Association Merit Award fuels three research avenues to tackle heart disease

CRISPR cures on the horizon: Breakthrough center aims to heal rare, deadly genetic diseases

Hidden identity of blood cancer revealed

Infammasomes provide a therapeutic target against human diseases

Research potentially expands options for patients with aggressive childhood cancer

Study reveals bidirectional association between autoimmune disease and perinatal depression

3D mini-organs from human fetal brain tissue unlock new frontier in brain research

New peptide library paves the way for targeting elusive cancer factor MYC

Three cytokine pairs found to be responsible for the body's damaging response to sepsis

Engineered virus-like particles power up gene editing, correcting blindness in mice

Comprehensive insights on pathophysiology and clinical management of atrial fibrillation

AI reveals hidden rules of cell neighborhoods in cancer

Gut microbiota: the new frontier in Alzheimer’s disease research and therapy

Genetic keys to COVID-19 vaccine response unlocked

Gut enzyme discovery sheds light on bilirubin balance in humans

Fruit fly research solves human disease and fuels new cancer immunotherapy approach

Discovery on housekeeping genetic elements reveals a novel avenue in cancer therapy

eBook: Using iPSCs models for human disease research and drug discovery eBook

Latest eBooks

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo