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Barrow research focuses on use of new technology for imaging brain tumors

Scientists at Barrow Neurological Institute have recently made discoveries about use of a new technology for imaging brain tumors in the operating room -- a finding that could have important implications for identifying and locating invading cells at the edge of a brain tumor.

5 May 2016

Scientists discover how immune system molecule hijacks brain circuit to reduce appetite during illness

Loss of appetite during illness is a common and potentially debilitating phenomenon--in cancer patients, especially, it can even shorten lifespan.

5 May 2016

Simple 20-second upper arm extension test can identify frailty in older adults

A simple arm test that employs a novel wearable technology can rapidly and accurately identify physiological frailty in older adults, according to study results published online in the Journal of the American College of Surgeons in advance of print publication.

5 May 2016

Study reveals glioblastoma subtypes tend to develop in different regions of the brain

Researchers at University of California San Diego School of Medicine have demonstrated that distinct types of glioblastoma, the most common form of brain cancer in adults, tend to develop in different regions of the brain. This finding provides an explanation for how the same cancer-causing mutation can give rise to different types of brain malignancies.

5 May 2016

Human brains constantly make statistical computations to estimate confidence

The directions, which came via cell phone, were a little garbled, but as you understood them: "Turn left at the 3rd light and go straight; the restaurant will be on your right side." Ten minutes ago you made the turn. Still no restaurant in sight. How far will you be willing to drive in the same direction?

5 May 2016

New research shows molecular, cellular processes in human embroyo development

Despite significant biomedical advances in recent decades, the very earliest events of human development¬--those that occur during a critical window just after fertilization--have remained an unobservable mystery, until now.

5 May 2016

New light-based technique may offer improved treatment for eye problems

Researchers have developed a new light-based technique that selectively stiffens tissue in the cornea and might one day offer improved treatment for eye problems caused by weakened corneal tissue.

5 May 2016

Innovative bone marrow-on-a-chip microdevice holds promise for developing improved radiation countermeasures

Engineered bone marrow grown in a novel microfluidic chip device responds to damaging radiation exposure followed by treatment with compounds that aid in blood cell recovery in a way that mimics living bone marrow.

5 May 2016

High-fructose diet during pregnancy may affect fetal growth

Consuming a high-fructose diet during pregnancy may cause defects in the placenta and restrict fetal growth, potentially increasing a baby's risk for metabolic health problems later in life, according to research in mice and people by a team at Washington University School of Medicine in St. Louis.

5 May 2016

Certain sugars in the body play key role in colitis, colon cancer development

An Oklahoma Medical Research Foundation scientist has discovered that certain sugars produced by the body play an important role in the development of colitis and, ultimately, colon cancer. The new finding could potentially lead to therapies for ulcerative colitis, Crohn's disease and colon cancer.

5 May 2016

Loyola researchers detect tumor gene that may help predict survival outcomes in mouth cancer patients

Loyola researchers have identified a tumor gene that may help to predict survival outcomes in patients with cancer of the mouth and tongue.

5 May 2016

BioTek to present new technologies for cell-based applications at analytica 2016

BioTek will present two opportunities for researchers to learn about new instruments and approaches to simplify their workflow at analytica 2016, the 25th International Trade Fair for Laboratory Technology, Analysis, Biotechnology and analytica conference.

5 May 2016

Blend of pulverized natural bone and man-made plastic can create 3D printed replacement bones

To make a good framework for filling in missing bone, mix at least 30 percent pulverized natural bone with some special man-made plastic and create the needed shape with a 3-D printer. That's the recipe for success reported by researchers at The Johns Hopkins University in a paper published April 18 online in ACS Biomaterials Science & Engineering.

5 May 2016

Research provides new insight into cellular composition of IDH1-mutant gliomas

Winner of the Preuss Research Award, Andrew Venteicher, MD, PhD, presented his research, Cellular Architecture of Human IDH1-mutant Gliomas Revealed Using Single-cell RNA Sequencing, during the 2016 American Association of Neurological Surgeons Annual Scientific Meeting.

5 May 2016

Bayer-new phase 3 liver cancer data

Bayer has announced that a Phase III trial evaluating its oncology compound Stivarga® (regorafenib) tablets for the treatment of patients with unresectable hepatocellular carcinoma (HCC) has met its primary endpoint of a statistically significant improvement in overall survival. The study, called RESORCE, evaluated the efficacy and safety of regorafenib in patients with HCC whose disease has progressed after treatment with sorafenib. The safety and tolerability were generally consistent with the known profile of regorafenib. Detailed efficacy and safety analyses from this study are expected to be presented at an upcoming scientific congress.

4 May 2016

Oral administration of Jakinibs reduces Parkinson's disease pathogenesis in rat model

University of Alabama at Birmingham researchers report the first documentation that suppressing a key cell-signaling pathway in a rat model of Parkinson's disease reduces pathogenesis. Oral administration of AZD1480 — one of the JAK/STAT pathway inhibitors generally known as Jakinibs — lessened the destructive inflammation and nerve cell degradation in the area of the brain affected by Parkinson's.

4 May 2016

LALES study analyzes risk, prevalence of early and late stage AMD among Latinos

The University of Southern California Roski Eye Institute researchers and clinicians published results of the largest population-based study of adult Latinos and age-related macular degeneration (AMD) in the National Eye Institute-funded "Los Angeles Latino Eye Study." The study, published in JAMA Ophthalmology, is the first to analyze the risk and prevalence of early and late stage AMD and its impact on quality of life for older Latinos.

4 May 2016

Scientists find that disruption to SCN rhythms can negatively impact overall health

Researchers have shown for the first time how neurons in the SCN are connected to each other, shedding light on this vital area of the brain. Understanding this structure — and how it responds to disruption — is important for tackling illnesses like diabetes and posttraumatic stress disorder. The scientists have also found that disruption to these rhythms such as shifts in work schedules or blue light exposure at night can negatively impact overall health.

4 May 2016

Scientists detect blood biomarker that may help in early diagnosis of children with ASD

Researchers at UT Southwestern Medical Center have identified a blood biomarker that may aid in earlier diagnosis of children with autism spectrum disorder, or ASD.

4 May 2016

Aggregation of SOD1 protein in nerve cells can lead to ALS

Persons with the serious disorder ALS, can have a genetic mutation that causes the protein SOD1 to aggregate in motor neurons in the brain and spinal cord. Researchers at Umea University have discovered that, when injected into mice, the SOD1 aggregation spreads rapidly leading to ALS. The discovery has been described in the Journal of Clinical Investigation.

4 May 2016

Cell News and Research

Barrow research focuses on use of new technology for imaging brain tumors

Scientists discover how immune system molecule hijacks brain circuit to reduce appetite during illness

Simple 20-second upper arm extension test can identify frailty in older adults

Study reveals glioblastoma subtypes tend to develop in different regions of the brain

Human brains constantly make statistical computations to estimate confidence

New research shows molecular, cellular processes in human embroyo development

New light-based technique may offer improved treatment for eye problems

Innovative bone marrow-on-a-chip microdevice holds promise for developing improved radiation countermeasures

High-fructose diet during pregnancy may affect fetal growth

Certain sugars in the body play key role in colitis, colon cancer development

Loyola researchers detect tumor gene that may help predict survival outcomes in mouth cancer patients

BioTek to present new technologies for cell-based applications at analytica 2016

Blend of pulverized natural bone and man-made plastic can create 3D printed replacement bones

Research provides new insight into cellular composition of IDH1-mutant gliomas

Bayer-new phase 3 liver cancer data

Oral administration of Jakinibs reduces Parkinson's disease pathogenesis in rat model

LALES study analyzes risk, prevalence of early and late stage AMD among Latinos

Scientists find that disruption to SCN rhythms can negatively impact overall health

Scientists detect blood biomarker that may help in early diagnosis of children with ASD

Aggregation of SOD1 protein in nerve cells can lead to ALS

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