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pIMAGO nanopolymer can test cancer drug efficacy against biochemical processes

A Purdue University scientist's nanopolymer would make it easier and cheaper for drug developers to test the effectiveness of a widely used class of cancer inhibitors.

17 Mar 2011

Harvard, UCI receive $2 million CDC grant to help reduce hospital-borne MRSA infections

A UC Irvine infectious disease specialist will be part of a nationwide Centers for Disease Control and Prevention research program to develop and test innovative approaches to reducing infection in healthcare settings.

17 Mar 2011

Scientist suggests breaking tangled mucus barrier can help treat cancer

Measuring the mechanical strength of cancer cell mucus layers provides clues about better ways to treat cancer, and also suggests why some cancer cells are more resistant to drugs than others, according to Kai-tak Wan, associate professor of engineering at Northeastern University, Boston, Mass.

17 Mar 2011

Researchers update 'Hallmarks of Cancer' seminal review

Renowned cancer researchers Robert Weinberg, a Founding Member of Whitehead Institute, and Douglas Hanahan, Director of the Swiss Institute for Experimental Cancer Research have updated their seminal review, "Hallmarks of Cancer," which has influenced the study of cancer and the development of therapeutics for more than a decade.

17 Mar 2011

UNAIDS, UNDP, WHO release policy brief advising countries on using TRIPS flexibilities to drive down HIV treatment costs

Amid growing concerns over the long-term sustainability of access to affordable HIV/AIDS drugs, UNAIDS, WHO and the U.N. Development Program on Tuesday released a policy brief advising countries on how they can successfully use rules written into the World Trade Organization Agreement on Trade-Related Aspects of Intellectual Property Rights to lower the cost of and increase access to HIV treatment, Intellectual Property Watch reports.

17 Mar 2011

ACEP, Poison Control Centers raise awareness about drug poisoning dangers

New visits for drug-related poisoning in the United States continue to rise; therefore, the American College of Emergency Physicians and the American Association of Poison Control Centers are raising awareness about the dangers of drug poisoning as part of Poison Prevention Week.

17 Mar 2011

Laser light can kill cancer cells by pumping drugs into them

Shining a laser light on cells and then clicking off the light makes the cells "breathe in" surrounding water, providing a potentially powerful delivery system for chemotherapy drugs, as well as a non-invasive way to target anti-Alzheimer's medicines to the brain. That's the conclusion of a report in ACS's The Journal of Physical Chemistry Letters.

17 Mar 2011

Gene therapy holds promise for Parkinson's treatment

A first-of-its-kind study of gene therapy in the treatment of Parkinson's disease determined that half of all patients who received the treatment had "clinically meaningful improvements" of their symptoms within six months of surgery.

17 Mar 2011

HGSI, FivePrime enter agreement to develop, commercialize FP-1039 for multiple cancers

Human Genome Sciences, Inc. and FivePrime Therapeutics, Inc. announced today that they have entered into an agreement to develop and commercialize FivePrime's FP-1039 product for multiple cancers.

17 Mar 2011

Pig model reveals how cystic fibrosis gene mutation causes disease

It's been more than 20 years since scientists first discovered the gene that causes cystic fibrosis (CF), yet questions about how the mutated gene causes disease remain unanswered.

17 Mar 2011

Experts to discuss work directions for fight against TB at ITM conference in Antwerp

On occasion of the World TB Day, leading experts from 12 countries will take stock of the fight against tuberculosis, during a conference at the Institute of Tropical Medicine in Antwerp.

17 Mar 2011

Pharmaron signs agreement to provide Isis with nucleoside phosphoramidites up to 100 kg

Pharmaron has signed an agreement to provide Isis Pharmaceuticals, Inc. with nucleoside phosphoramidites at quantities up to 100 kg. Nucleoside phosphoramidites are fundamental building blocks in the production of antisense therapeutics.

17 Mar 2011

Scientists create new drug delivery system to treat cancer

Scientists in Syracuse University's Chemistry Department have created a new drug delivery system expected to advance the effectiveness of cancer-killing drugs. It uses gold nanoparticles with attached DNA that binds to a proven anti-cancer drug, Doxorubicin or DOX.

16 Mar 2011

It's the health law's birthday and not everyone is celebrating

The health overhaul's first anniversary — just about a week away — is already being marked on Capitol Hill with a number of hearings and other events related to exploring, complimenting and criticizing the law's implementation.

16 Mar 2011

Researcher argues against use of Cop1-inhibitory drugs for cancer treatment

Jean-Christophe Marine strongly argues against the use of Cop1-inhibitory drugs. The protein Cop1 has -for a long time - been seen as an attractive drug target for cancer. But Jean-Christophe Marine found out that Cop1 acts as a tumor suppressor, and thus inhibits tumor formation. His new data will have direct implications for the development of cancer drug targets.

16 Mar 2011

China Nepstar Chain Drugstore fourth quarter revenues increase 1.0% to US$95 million

China Nepstar Chain Drugstore Ltd., the largest retail drugstore chain in China based on the number of directly operated stores, today announced its unaudited financial results for the fourth quarter and fiscal year ended December 31, 2010.

16 Mar 2011

Researchers discover 3-D structure of key biological receptor

Researchers have solved the three-dimensional structure of a key biological receptor. The finding has the potential to speed drug discovery in many areas, from arthritis to respiratory disorders to wound healing, because it enables chemists to better examine and design molecules for use in experimental drugs.

16 Mar 2011

New study on how epoxyeicosatrienoic acids protect kidneys

Researchers at Georgia Health Sciences University are studying whether inhibiting an enzyme that reduces levels of a protective metabolite could halt the progression of diabetic nephropathy, or kidney disease resulting from diabetes.

16 Mar 2011

Updated NCCN Guidelines for Ovarian Cancer outline new treatment options for women

Although finding effective screening tools remains a priority, new treatment options for women with ovarian cancer, such as the ones outlined in the updated NCCN Guidelines for Ovarian Cancer, are vital to making steady progress against the disease according to Robert J. Morgan, MD, of City of Hope Comprehensive Cancer Center and chair of the NCCN Guidelines Panel for Ovarian Cancer.

16 Mar 2011

On The Issues Magazine examines how environmental health affects women's lives

The Spring 2011 edition of On The Issues Magazine – "The Ecology of Women" – examines how environmental health affects women's lives, particularly the toxins and chemicals that enter our bodies from the air, water, food and consumer products. These toxins are implicated as possible causes of conditions like cancer, early puberty, infertility, miscarriages, and birth defects.

16 Mar 2011