Fatigue News and Research

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Novel drug atezolizumab harnesses immune system to shrink tumors in advanced bladder cancer

A new drug that harnesses the immune system to attack tumors is highly effective against advanced bladder cancer, according to the results of an international clinical trial to be presented June 5 at the annual meeting of the American Society for Clinical Oncology.

6 Jun 2016

Nivolumab drug shows better response rate in metastatic bladder cancer patients

The immune checkpoint blockade drug nivolumab reduced tumor burden in 24.4 percent of patients with metastatic bladder cancer, regardless of whether their tumors had a biomarker related to the drug's target, according to clinical trial results from The University of Texas MD Anderson Cancer Center.

6 Jun 2016

New review explores health impacts of adults participating in environmental enhancement activities

A team of Cochrane authors based in the UK and led by an academic from Plymouth University Peninsula Schools of Medicine and Dentistry, has carried out a review investigating the health benefit of contact with the natural environment.

3 Jun 2016

Scientists use new technique to repair fibrotic liver cells within the organ

Advances in stem cell research have made it possible to convert patients' skin cells into heart cells, kidney cells, liver cells and more in the lab dish, giving researchers hope that one day such cells could replace organ transplantation for patients with organ failure.

3 Jun 2016

FDA approves blood-based cobas EGFR Mutation Test v2 for NSCLC patients

The U.S. Food and Drug Administration today approved the cobas EGFR Mutation Test v2, a blood-based companion diagnostic for the cancer drug Tarceva (erlotinib). This is the first FDA-approved, blood-based genetic test that can detect epidermal growth factor receptor (EGFR) gene mutations in non-small cell lung cancer patients.

2 Jun 2016

Ocaliva drug gets FDA approval for primary biliary cholangitis treatment

On Friday, May 27, the U.S. Food and Drug Administration granted accelerated approval for Ocaliva (obeticholic acid) for the treatment of primary biliary cholangitis (PBC) in combination with ursodeoxycholic acid (UDCA) in adults with an inadequate response to UDCA, or as a single therapy in adults unable to tolerate UDCA.

1 Jun 2016

$Review outlines fatigue, fracture behavior of wire-based systems used in biomedical applications$

Review outlines fatigue, fracture behavior of wire-based systems used in biomedical applications

Gbur and Lewandowski, of Case Western Reserve University, have published an extensive review of the fatigue and fracture behavior of wire-based systems used in biomedical applications in International Materials Reviews.

28 May 2016

Self-care can help nurses manage compassion fatigue

The heart of healthcare is stressed. With longer shifts, staffing shortages and healthcare changes taxing our nurses, it's no surprise that up to 80 percent report suffering compassion fatigue at some point in their careers, according to recent studies.

26 May 2016

Researchers find potential link between pulmonary function and vocal fatigue symptoms in women

Teaching is an occupation with a high risk of developing vocal problems -- teachers have more than twice the voice problems than people in other professions, as the voice is the major tool in classroom instruction and is often used for long periods of time and in noisy environments.

26 May 2016

Shoulder, arm pain could stem from thoracic outlet syndrome

Shoulder and arm pain come with the territory for some athletes and certain occupations like hair stylists, mechanics, even office workers.

26 May 2016

The National MDS Study aims to identify causes, genetic makeup of fatal blood diseases

The National Myelodysplastic Syndromes Natural History Study is underway, the ECOG-ACRIN Cancer Research Group and its collaborators announced today.

26 May 2016

AF-related symptoms and quality of life worse in women

Women with atrial fibrillation experience more severe symptoms, a lower quality of life and a higher risk of stroke than men, but they have better overall survival, US study data show.

24 May 2016

Telephone-based intervention helps reduce menopause-related insomnia, hot flashes

Chatting on the phone with a "sleep coach" and keeping a nightly sleep diary significantly improve sleep quality and reduce insomnia in women through all stages of menopause, according to a new study published today in JAMA Internal Medicine.

24 May 2016

Investigational drug abemaciclib shows durable clinical activity for variety of cancer types

The investigational anticancer therapeutic abemaciclib, which targets CDK4 and CDK6, showed durable clinical activity when given as continuous single-agent therapy to patients with a variety of cancer types, including breast cancer, non-small cell lung cancer (NSCLC), glioblastoma, and melanoma, according to results from a phase I clinical trial.

23 May 2016

Tecentriq drug gets FDA approval to treat urothelial carcinoma

The U.S. Food and Drug Administration today approved Tecentriq (atezolizumab) to treat the most common type of bladder cancer, called urothelial carcinoma. This is the first product in its class (PD-1/PD-L1 inhibitors) approved to treat this type of cancer.

19 May 2016

Wyss Institute partners with ReWalk to accelerate development of wearable, soft exosuits

The Wyss Institute for Biologically Inspired Engineering at Harvard University has entered into a collaboration with ReWalk Robotics Ltd., to accelerate the development of the Institute's lightweight, wearable soft exosuit technologies for assisting people with lower limb disabilities.

18 May 2016

Study finds greater activation of biological fight or flight mechanism in chronic fatigue syndrome patients

Chronic fatigue syndrome patients report they are more anxious and distressed than people who don't have the condition, and they are also more likely to suppress those emotions.

18 May 2016

Phase 2 results of AbbVie’s venetoclax in patients with R/R CLL with 17p deletion published in The Lancet Oncology

AbbVie, a global biopharmaceutical company, today announced The Lancet Oncology published results from the Phase 2, single arm, open label trial studying venetoclax in patients with relapsed/refractory (R/R) chronic lymphocytic leukaemia (CLL) with 17p deletion.

17 May 2016

Experimental hepatitis C drug slows down development of Zika in mice

Virologists from KU Leuven, Belgium, have shown that an experimental antiviral drug against hepatitis C slows down the development of Zika in mice. The research team was led by Professor Johan Neyts from the Laboratory of Virology and Chemotherapy.

17 May 2016

FDA approves additional indication for Eisai's anticancer agent Lenvima in combo with Everolimus for advanced renal cell carcinoma

Eisai Co., Ltd. has announced that its U.S. subsidiary Eisai Inc. has received approval from the U.S. Food and Drug Administration (FDA) for an additional indication for Eisai's in-house developed novel anticancer agent Lenvima (lenvatinib mesylate) in combination with everolimus for the treatment of patients with advanced renal cell carcinoma following one prior anti-angiogenic therapy.

16 May 2016

Fatigue News and Research

Novel drug atezolizumab harnesses immune system to shrink tumors in advanced bladder cancer

Nivolumab drug shows better response rate in metastatic bladder cancer patients

New review explores health impacts of adults participating in environmental enhancement activities

Scientists use new technique to repair fibrotic liver cells within the organ

FDA approves blood-based cobas EGFR Mutation Test v2 for NSCLC patients

Ocaliva drug gets FDA approval for primary biliary cholangitis treatment

Review outlines fatigue, fracture behavior of wire-based systems used in biomedical applications

Self-care can help nurses manage compassion fatigue

Researchers find potential link between pulmonary function and vocal fatigue symptoms in women

Shoulder, arm pain could stem from thoracic outlet syndrome

The National MDS Study aims to identify causes, genetic makeup of fatal blood diseases

AF-related symptoms and quality of life worse in women

Telephone-based intervention helps reduce menopause-related insomnia, hot flashes

Investigational drug abemaciclib shows durable clinical activity for variety of cancer types

Tecentriq drug gets FDA approval to treat urothelial carcinoma

Wyss Institute partners with ReWalk to accelerate development of wearable, soft exosuits

Study finds greater activation of biological fight or flight mechanism in chronic fatigue syndrome patients

Phase 2 results of AbbVie’s venetoclax in patients with R/R CLL with 17p deletion published in The Lancet Oncology

Experimental hepatitis C drug slows down development of Zika in mice

FDA approves additional indication for Eisai's anticancer agent Lenvima in combo with Everolimus for advanced renal cell carcinoma

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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