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Mutant KRAS and P53 promote growth and metastasis of pancreatic cancer

Researchers at The University of Texas MD Anderson Cancer Center have discovered that mutant KRAS and p53, the most frequently mutated genes in pancreatic cancer, interact through the CREB1 protein to promote metastasis and tumor growth.

12 Apr 2021

Advanced computer model could lead to improvements in 'bionic eye' technology

There are millions of people who face the loss of their eyesight from degenerative eye diseases. The genetic disorder retinitis pigmentosa alone affects 1 in 4,000 people worldwide.

9 Apr 2021

Researchers uncover the mysteries of sleep disorders in multiple system atrophy

Multiple system atrophy (MSA) is a neurodegenerative disease with multiple debilitating symptoms. One of them is sleep disorders; however, owing to limited research, little is known about why only some patients are affected, how sleep disorders influence MSA severity, or even how sleep disorders vary across different MSA subtypes.

9 Apr 2021

Asymptomatic SARS-CoV-2 individuals with blood group AB at highest risk

Scientists worldwide are conducting extensive research to understand the nature of the virus, its transmission kinetics, etc. They have found a strong correlation between the ABO blood group and SARS-CoV-2 regarding its morbidity and mortality.

9 Apr 2021

Study finds more children infected by coronavirus during the second wave in Germany

A study by Helmholtz Zentrum München concludes that during the second Corona wave, three to four times more children in Bavaria, Germany were infected with the Corona virus than reported via PCR tests.

8 Apr 2021

Prefusion SARS-CoV-2 spike-based vaccine candidate shows high safety and efficacy in phase I trial

A new preprint research paper posted to the medRxiv server reports the results of the first human trial of the prefusion stabilized SARS-CoV-2 spike vaccine MVC-COV1901 in Taiwan.

8 Apr 2021

Eliminating racism and anti-LGBTQ policies can improve the health of black sexual minority men

Eliminating racist and anti-LGBTQ policies is essential to improving the health of Black gay, bisexual and other sexual minority men, according to a Rutgers-led research team.

8 Apr 2021

Study shows how signal propagation circuit is modulated by attention

To effectively perform any daily task, the human brain needs to process information from the outside world using various cognitive functions. This cognitive processing passes through a dense interconnected network of cells whose physiology is specialized.

8 Apr 2021

Step length synergy while crossing obstacles found to be lower in Parkinson’s patients

A multidisciplinary research group affiliated with the Department of Physical Education's Human Movement Laboratory at São Paulo State University in Bauru, Brazil, measured step length synergy while crossing obstacles in patients with Parkinson's disease and concluded that it was 53% lower than in healthy subjects of the same age and weight. Step length is one of the main variables affected by the disease.

7 Apr 2021

Hopkins Medicine endocrinologist publishes first clinical practice review on diabetes management

New medicines for people who have diabetes seem to pop up all the time. Drugs that help the body break down carbohydrates, drugs that increase excretion of glucose in the urine, drugs that help muscles respond to insulin and drugs that stimulate the pancreas to produce it - the list of pharmaceutical options to treat diabetes gets longer and longer.

7 Apr 2021

A proprioceptive control strategy for management of low back pain

Low back pain in the elderly is the result of poor “proprioception,” or the body’s ability to perceive its own position in space, caused by a deterioration of sensory receptors in their muscles called proprioceptors.

7 Apr 2021

Researchers identify novel SARS-CoV-2 variant unregistered on genomic sequence databases

A team of scientists from the University of California Santa Cruz, USA, recently identified a novel variant (B.1.x) of SARS-CoV-2 that might be circulating in at least 20 US states and six countries globally.

7 Apr 2021

Enhanced neutralization of SARS-CoV-2 South African variant with heterologous adjuvant vaccine candidate

A new study describes the use of a single dose of vaccine based on the viral protein called the receptor-binding domain (RBD) to elicit powerful neutralizing activity against both the Wuhan strain and the most concerning VOC called the South African (SA) strain.

7 Apr 2021

Family meals, conviviality, and the Mediterranean diet promote healthy eating among adolescents

Eating together as a family, maintaining the Mediterranean diet's traditional customs of conviviality, influences the eating habits of adolescents and prevents eating behaviour disorders, according to a new study prepared by scientists from the Universitat Oberta de Catalunya and the Universitat Autònoma de Barcelona and published in the open access International Journal of Environmental Research and Public Health.

6 Apr 2021

Researchers identify a novel SARS-CoV-2 variant (A.VOI.V2) in southern Africa

Scientists recently explored the transmission dynamics of currently circulating variants of SARS-CoV-2 in a southern African country. By analyzing the genomic sequences of these variants, they have identified a novel SARS-CoV-2 variant with multiple spike mutations. They have temporarily designated the variant A.VOI.V2.

6 Apr 2021

Research explores sex differences in placental defenses against SARS-CoV-2 infection

A plethora of earlier studies has reported on the differences between the sexes in susceptibility to the currently circulating severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), as well as its severity. A new preprint research paper posted to the bioRxiv* server extends this to the placenta in pregnancy.

6 Apr 2021

Contraception counseling, pregnancy planning are necessary to optimize health of women with heart disease

Pregnancy can increase the risk of morbidity and mortality in women with cardiovascular disease; however, many cardiologists are not having pre-pregnancy contraception discussions with their patients of child-bearing age.

5 Apr 2021

Study finds CD8+ T cell responses detect all major SARS-CoV-2 variants

There have been concerns that several SARS-CoV-2 variants have mutations that allow them to evade the immune system. A new study published in the Open Forum Infectious Diseases suggests otherwise. Led by Aaron AR Tobian of Johns Hopkins University School of Medicine, results showed that except for one from the B.1.351 variant, CD8+ T cells showed a broad response to all SARS-CoV-2 variants.

2 Apr 2021

Wearing helmet during a crash associated with more arm and hand injuries

Maybe parents are right to bristle when their infatuated offspring brings home a motorcycle rider: despite only making up 10% of vehicles on US roads, motorcycle riders comprise 40% of all traffic accident trauma patients.

1 Apr 2021

New study aims to develop population-based dietary assessment mobile app

Excessive intakes of saturated fat and added sugar are a leading cause of premature mortality among adults in the U.S., contributing to nearly 700,000 deaths each year, but nutritional research aimed at improving health is often challenging due to limitations in accurately tracking participants' food intake.

1 Apr 2021

Frequency News and Research

Mutant KRAS and P53 promote growth and metastasis of pancreatic cancer

Advanced computer model could lead to improvements in 'bionic eye' technology

Researchers uncover the mysteries of sleep disorders in multiple system atrophy

Asymptomatic SARS-CoV-2 individuals with blood group AB at highest risk

Study finds more children infected by coronavirus during the second wave in Germany

Prefusion SARS-CoV-2 spike-based vaccine candidate shows high safety and efficacy in phase I trial

Eliminating racism and anti-LGBTQ policies can improve the health of black sexual minority men

Study shows how signal propagation circuit is modulated by attention

Step length synergy while crossing obstacles found to be lower in Parkinson’s patients

Hopkins Medicine endocrinologist publishes first clinical practice review on diabetes management

A proprioceptive control strategy for management of low back pain

Researchers identify novel SARS-CoV-2 variant unregistered on genomic sequence databases

Enhanced neutralization of SARS-CoV-2 South African variant with heterologous adjuvant vaccine candidate

Family meals, conviviality, and the Mediterranean diet promote healthy eating among adolescents

Researchers identify a novel SARS-CoV-2 variant (A.VOI.V2) in southern Africa

Research explores sex differences in placental defenses against SARS-CoV-2 infection

Contraception counseling, pregnancy planning are necessary to optimize health of women with heart disease

Study finds CD8+ T cell responses detect all major SARS-CoV-2 variants

Wearing helmet during a crash associated with more arm and hand injuries

New study aims to develop population-based dietary assessment mobile app

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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