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Genetic mechanisms at play in blood cells important in Parkinson’s disease

What does the genetics of blood cells have to do with brain cells related to Parkinson's disease? From an unusual collaboration of neurologists and a pharmacologist comes the surprising answer: Genetic mechanisms at play in blood cells also control a gene and protein that cause Parkinson's disease.

21 Jul 2008

Suckling infants trigger surges of trust hormone in mothers' brains

Researchers from the University of Warwick, in collaboration with other universities and institutes in Edinburgh, France and Italy, have for the first time been able to show exactly how, when a baby suckles at a mother's breast, it starts a chain of events that leads to surges of the "trust" hormone oxytocin being released in their mothers brains.

17 Jul 2008

Virus injection could offer long term relief for Parkinson's

Gene therapy could offer a new, long-lasting way to treat Parkinson's disease, research results announced Tuesday 15 July at FENS 2008 suggest. Dr Deniz Kirik of the University of Lund in Sweden has been using viruses to insert a new combination of genes into animals' brains, where they help produce the dopamine that is lacking in Parkinson's disease. The results suggest the treatment is very effective in animal models for several months, possibly years.

15 Jul 2008

Huntington's disease brain damage linked to overactive immune response in the bloodstream

The damage to brain tissue seen in Huntington's disease may be caused by an overactive immune response in the bloodstream and the brain, according to new findings from two teams of researchers at the University of Washington in Seattle and University College London. The findings will be published online July 14 in the Journal of Experimental Medicine.

14 Jul 2008

Stem cells help keep the brain healthy and active

For some years, scientists have been speculating over why stem cells exist in the brain, as brain regeneration is limited. A German team of neuroscientists believe these stem cells help keep the brain healthy and active.

13 Jul 2008

Researchers discover that learning suffers if brain transcript isn't transported far out to end of neurons

Neuroscientists at Georgetown University Medical Center have solved a mystery that lies at the heart of human learning, and they say the solution may help explain some forms of mental retardation as well as provide clues to overall brain functioning.

10 Jul 2008

Common mechanisms may underlie autism's diverse mutations

Many of the seemingly disparate mutations recently discovered in autism may share common underlying mechanisms, say researchers supported in part by the National Institute of Mental Health (NIMH), a part of the National Institutes of Health (NIH). The mutations may disrupt specific genes that are vital to the developing brain, and which are turned on and off by experience-triggered neuronal activity.

10 Jul 2008

Researchers identify brain cells related to fear - paves way for more effective PTSD treatments

The National Institute of Mental Health estimates that in any given year, about 40 million adults (18 or older) will suffer from some form of anxiety disorder, including debilitating conditions such as phobias, panic disorders and post-traumatic stress disorder (PTSD). It is estimated that nearly 15 percent of U.S. soldiers returning from Iraq and Afghanistan develop PTSD, underscoring the urgency to develop better treatment strategies for anxiety disorders.

10 Jul 2008

Researchers measure movements smaller than one-billionth of a meter in ion channels

Each thought or action sends a million electrical signals pulsing through your body. At the heart of the process of generating these electrical impulses is the ion channel.

10 Jul 2008

Novel drug ionophore shows potential for Alzheimer's

Scientists report a remarkable improvement in Alzheimer's transgenic mice following treatment with a new drug. The study, published by Cell Press in the July 10th issue of the journal Neuron, provides the first demonstration that an ionophore, a compound that transports metal ions across cell membranes, can elicit rapid and pronounced improvement in neuropathology and cognitive function in mouse models of Alzheimer's Disease (AD).

10 Jul 2008

Neuron to publish Prana's PBT2 preclinical research on Alzheimer's disease

Prana Biotechnology Ltd. has announced the publication of key research findings with its lead Alzheimer's Disease drug, PBT2.

10 Jul 2008

An analysis of food's affect on the brain

In addition to helping protect us from heart disease and cancer, a balanced diet and regular exercise can also protect the brain and ward off mental disorders.

9 Jul 2008

The good and bad side of dopamine

The chemical dopamine induces both desire and dread, according to new animal research in the July 9 issue of The Journal of Neuroscience. Although dopamine is well known to motivate animals and people to seek positive rewards, the study indicates that it also can promote negative feelings like fear.

9 Jul 2008

Genetic change in dopamine transporter supports a role for dopamine signaling in ADHD

A genetic change in the dopamine transporter - one of the brain's dopamine-handling proteins - makes it behave as if amphetamine is present and "run backward," Vanderbilt University Medical Center investigators report this week in The Journal of Neuroscience.

9 Jul 2008

Stopping drinking may lead to health problems including depression

Scientific evidence has long suggested that moderate drinking offers some protection against heart disease, certain types of stroke and some forms of cancer.

8 Jul 2008

Transgenic tomatoes as edible vaccine carriers for Alzheimer's disease

The humble tomato could be a suitable carrier for an oral vaccine against Alzheimer's disease, according to HyunSoon Kim from the Korea Research Institute of Bioscience and Biotechnology (KRIBB) in Korea and colleagues from Digital Biotech Inc. and the Department of Biological Science at Wonkwang University.

8 Jul 2008

UAB joins elite brain cancer research group

Brain cancer experts at the University of Alabama at Birmingham (UAB) have been selected for membership in the Ivy Genomics-Based Medicine Project. The project is a national consortium of cutting-edge hospitals and academic centers working to improve treatment and survival for patients with a kind of malignant brain tumor called a glioma.

8 Jul 2008

Researchers detail types of genes necessary for brain

Researchers from Harvard Medical School and Brandeis University have successfully completed a full-genome RNAi screen in neurons, showing what types of genes are necessary for brain development. Details of the screen and its novel methodology are published July 4th in the open-access journal PLoS Genetics.

8 Jul 2008

Japanese encephalitis damages the brain in two ways

Japanese encephalitis (JE), commonly known as brain fever, is one of the prevalent mosquito-borne encephalitis in India and entire South East (SE) Asia.

8 Jul 2008